Critical Illness
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: Tight Glycemic Control With Intensive Insulin Therapy in PICU [Phase 2]
A Phase 2 clinical trial update evaluating tight glycemic control with intensive insulin therapy in critically ill patients in the pediatric…
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CLINICAL_TRIALS trial_result · 2022-02-08Clinical Trial Update: Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients [NA]
A completed clinical trial evaluating a rehabilitation strengthening and mobility program for ventilator-dependent older patients; results p…
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CLINICAL_TRIALS trial_result · 2021-12-13Clinical Trial Update: Body Positioning and Pulmonary Aeration During Mechanical Ventilation [NA]
Clinical trial update on body positioning and pulmonary aeration during mechanical ventilation in critically ill patients; study terminated …
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CLINICAL_TRIALS trial_result · 2021-12-10Clinical Trial Update: Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock [Phase 2, Phase 3]
A clinical trial evaluating hydrocortisone, vitamin C, and thiamine for septic shock was terminated after phases 2 and 3.
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CLINICAL_TRIALS trial_result · 2021-11-11Clinical Trial Update: Second Survey of Intensive Care in India
A completed clinical trial update from the Intensive Care in India survey assessing outcomes in critical illness; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-11-05Clinical Trial Update: DOSE Trial of Opioid Sparing Effect [Phase 1]
Phase 1 trial update on opioid-sparing effects of dexmedetomidine in mechanically ventilated, critically ill patients; study terminated with…
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CLINICAL_TRIALS trial_result · 2021-09-10Clinical Trial Update: Exploration of Investigating ICU Mobilisation With Vasoactive Drugs
A completed clinical trial investigating ICU mobilization in patients receiving vasoactive drugs; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-08-04Clinical Trial Update: Sleep Intervention During Acute Lung Injury [Phase 4]
Phase 4 clinical trial update on sleep intervention during acute lung injury/critical illness has completed.
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CLINICAL_TRIALS trial_result · 2021-07-29Clinical Trial Update: Intravenous Versus Subcutaneous Administration of Low Molecular Weight Heparin for Thromboprophylaxis in Critically Ill Patients [Phase 4]
Phase 4 trial comparing intravenous versus subcutaneous administration of low molecular weight heparin for thromboprophylaxis in critically …
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CLINICAL_TRIALS trial_result · 2021-06-25Clinical Trial Update: Measuring the Metabolic Cost of Fever
A terminated clinical trial investigating the metabolic cost of fever in pediatric critical illness; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-05-26Clinical Trial Update: Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients [Phase 4]
Phase 4 clinical trial update on the efficacy and safety of a heparin-coated surface-treated polyacrylonitrile membrane hemofilter in critic…
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients [Phase 3]
Phase 3 clinical trial evaluating an analgosedative adjunct ketamine infusion in mechanically ventilated ICU patients has completed.
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CLINICAL_TRIALS withdrawal · 2021-05-05Clinical Trial Update: The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit [Phase 3]
Phase 3 trial investigating naloxegol for refractory constipation in critically ill patients was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Conservative Versus Conventional Oxygen Administration in Critically Ill Patients [Phase 4]
Phase 4 clinical trial comparing conservative versus conventional oxygen administration in critically ill patients; status and results not d…
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CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: Balanced Solution Versus Saline in Intensive Care Study [Phase 3]
Phase 3 trial comparing Balanced Solution to saline in critically ill patients with acute kidney injury has completed.
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CLINICAL_TRIALS trial_result · 2021-04-06Clinical Trial Update: Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients [NA]
A completed clinical trial evaluating enhanced protein-energy provision via the enteral route in critically ill patients; results posted in …
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CLINICAL_TRIALS research · 2021-03-18Clinical Trial Update: Ceftaroline Pharmacokinetics in Continuous Renal Replacement Therapy [Phase 4]
A Phase 4 trial update on how ceftaroline pharmacokinetics behave during continuous renal replacement therapy in critically ill patients wit…
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: A Study to Investigate the Effect of HMB on Skeletal Muscle Wasting in Early Critical Illness [Phase 2]
Phase 2 clinical trial investigating the effect of HMB on skeletal muscle wasting in early critical illness is listed with an unknown status…
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CLINICAL_TRIALS trial_result · 2021-03-16Clinical Trial Update: Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients (TOP-UP) [Phase 3]
A Phase 3 trial (TOP-UP) evaluating supplemental parenteral nutrition in underweight and overweight critically ill patients was terminated; …
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: Use of Nudges To Enhance Enrollment in Critical Care Research [NA]
Clinical trial update evaluating whether nudges can improve enrollment in critical care research; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-17Clinical Trial Update: Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients [Phase 4]
A Phase 4 clinical trial comparing clonidine to dexmedetomidine for agitation in intensive care unit delirium.
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CLINICAL_TRIALS trial_result · 2020-12-14Clinical Trial Update: REVERSE-AKI Randomized Controlled Pilot Trial [Phase 2]
A Phase 2 randomized pilot trial (REVERSE-AKI) focusing on acute kidney injury in critically ill patients has been completed.
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CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: PEP uP Protocol in Surgical Patients [Phase 4]
Phase 4 clinical trial update for the PEP uP protocol in surgical critically ill patients; study terminated with results posted.
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CLINICAL_TRIALS research · 2020-10-22Clinical Trial Update: Standard Issue Transfusion Versus Fresher Red Blood Cell Use in Intensive Care- A Randomised Controlled Trial [Phase 3]
A Phase 3 randomized trial comparing standard issue transfusion versus fresher red blood cell use in intensive care patients has completed a…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Reaching Protein Target With SmofKabiven® Extra Nitrogen vs Olimel N9E During the Early Phase of Acute Critical Illness [Phase 4]
A Phase 4 clinical trial comparing SmofKabiven Extra nitrogen versus Olimel N9E in the early phase of acute critical illness was terminated.