Critical Illness
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Midodrine for the Early Liberation of Vasopressor Support in the ICU [Phase 4]
Phase 4 clinical trial update evaluating midodrine for early liberation of vasopressor support in critically ill patients with shock.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Efficacy and Safety of Fospropofol Disodium Versus Propofol for Sedation in Mechanically Ventilated ICU Patients [Phase 2]
Phase 2 trial comparing fospropofol disodium to propofol for sedation in mechanically ventilated ICU patients completed an efficacy and safe…
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients [Phase 3]
Phase 3 trial update on selective decontamination of the digestive tract in ICU patients with critical illness and sepsis.
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Assessment of the Anti-inflammatory Effect of Heparin Infusion Versus Subcutaneous Injection in Septic Patients [Phase 2]
Phase 2 trial comparing anti-inflammatory effects of heparin infusion versus subcutaneous injection in septic, critically ill patients has c…
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CLINICAL_TRIALS trial_result · 2023-07-05Clinical Trial Update: Efficacy and Safety of Fospropofol Disodium Versus Propofol for Deep Sedation in Critically Ill Patients [Phase 2]
Phase 2 clinical trial comparing fospropofol disodium to propofol for deep sedation in critically ill patients; efficacy and safety data not…
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Metoclopramide on Gastric Emptying in Mechanically Ventilated Patients [Phase 4]
Phase 4 trial assessing metoclopramide for gastric emptying in mechanically ventilated patients has completed.
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: Tight Versus Liberal Blood Glucose Control in Adult Critically Ill Patients [Phase 3]
A Phase 3 trial evaluating tight versus liberal blood glucose control in adult critically ill patients with hyperglycemia.
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CLINICAL_TRIALS trial_result · 2023-05-26Clinical Trial Update: Long-term Sedation With Remimazolam Besylate in Critically Ill Patients [Phase 3]
Phase 3 clinical trial update investigating long-term sedation with remimazolam besylate in critically ill patients requiring light sedation…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Esketamine Induction Intubation in ICU Patients. [Phase 4]
A Phase 4 clinical trial update on Esketamine induction for intubation in critically ill ICU patients; current status is unknown.
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CLINICAL_TRIALS trial_result · 2023-04-27Clinical Trial Update: Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs. [Phase 3]
A phase 3 randomized trial compares safety and efficacy of dexmedetomidine versus midazolam in pediatric ICU patients beyond 24 hours.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Efficacy of Testosterone Gel to Restore Normal Serum Values of Testosterone During the Acute Phase of Critical Illness in Adult ICU Patients [Phase 2]
Phase 2 clinical trial assessing testosterone gel to restore normal testosterone levels during the acute phase of critical illness in adult …
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: Lorazepam Sedation for Critically Ill Children [Phase 2, Phase 3]
Phase 2/3 trial update on lorazepam sedation in critically ill children has completed.
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: Efficacy and Safety of Nafamostat Mesylate for VV-ECMO Anticoagulation [Phase 2]
Phase 2 clinical trial update investigating nafamostat mesylate for anticoagulation during VV-ECMO in critical illness.
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CLINICAL_TRIALS research · 2023-02-10Clinical Trial Update: The Prognostic Impact of Selenium On Critical Surgical Patients [Phase 4]
Phase 4 clinical trial evaluating the prognostic impact of selenium in critically ill patients, including those with selenium deficiency and…
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CLINICAL_TRIALS withdrawal · 2022-12-15Clinical Trial Update: The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function [Phase 3]
Phase 3 trial investigating CVVH fluid removal effects on intra-abdominal pressure and kidney function was withdrawn.
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CLINICAL_TRIALS trial_result · 2022-12-05Clinical Trial Update: Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation [Phase 3]
Phase 3 trial investigating propranolol as an anxiolytic to reduce sedative use in critically ill adults on mechanical ventilation; study co…
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Effects of Ketosis on Muscle Kinetics and Signaling During Critical Illness. [Phase 2]
A Phase 2 clinical trial evaluating the effects of ketosis on muscle kinetics and signaling in critically ill patients with ICU-acquired wea…
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Safety and Efficacy of Acetaminophen in the Intensive Care Unit. [Phase 4]
Phase 4 clinical trial on safety and efficacy of acetaminophen in critically ill patients with fever was terminated; results posted.
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CLINICAL_TRIALS withdrawal · 2022-10-27Clinical Trial Update: The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trial [Phase 3]
A Phase 3 multicenter randomized trial examining higher protein dosing in critically ill patients was withdrawn.
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CLINICAL_TRIALS trial_result · 2022-09-26Clinical Trial Update: Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Critically Ill Patients With Deep Sedation [Phase 2]
Phase 2 trial comparing remimazolam besylate to propofol for deep sedation in critically ill patients, focusing on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2022-09-15Clinical Trial Update: Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Mechanically Ventilated ICU Patients [Phase 2]
Phase 2 trial comparing remimazolam besylate to propofol for sedation in mechanically ventilated ICU patients completed, reporting efficacy …
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: Transcutaneous Diaphragm Electrical Stimulation in Critically Ill Patients [Phase 4]
Phase 4 clinical trial update on transcutaneous diaphragm electrical stimulation in critically ill patients undergoing mechanical ventilatio…
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CLINICAL_TRIALS trial_result · 2022-06-10Clinical Trial Update: The Energy Dose Study [Phase 2]
Phase 2 clinical trial update for The Energy Dose Study has terminated; results were posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-05-11Clinical Trial Update: Haloperidol for Delirium in Adult Critically Ill Patients [Phase 3]
A Phase 3 trial evaluating haloperidol for delirium in adult critically ill patients has been terminated.
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CLINICAL_TRIALS withdrawal · 2022-05-10Clinical Trial Update: Dexmedetomidine Cycling and Sleep in the Pediatric ICU [Phase 4]
Phase 4 clinical trial on dexmedetomidine cycling and sleep in pediatric ICU; study withdrawn.