Cowden Syndrome
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Cancer Risk Assessment in Patients With a Constitutional Alteration of the PTEN Gene
A clinical trial sponsored by Institut Bergonié is evaluating cancer risk assessment in individuals with constitutional PTEN gene alteration…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results [NA]
A clinical trial update from Memorial Sloan Kettering Cancer Center describes a study to boost genetic testing in families with potential ca…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations [Phase 2, Phase 3]
A double-blind trial of everolimus to improve social abilities in individuals with PTEN germline mutations. The study includes Cowden syndro…
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: Sirolimus for Cowden Syndrome With Colon Polyposis [Phase 2]
Phase 2 clinical trial of sirolimus for Cowden syndrome with colon polyposis has completed, sponsored by Ohio State University. The study ta…
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer [Phase 1, Phase 2]
Phase I/II trial update for BGT226 in adults with advanced solid malignancies including breast cancer; study completed.
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis
This clinical trial update from Hôpital Edouard Herriot describes a French cohort of patients with several hereditary polyposis syndromes (f…
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CLINICAL_TRIALS trial_result · 2013-07-19Clinical Trial Update: Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes [Phase 2]
A Phase 2 trial evaluated sirolimus for Cowden syndrome and related PTEN hamartoma tumor syndromes and has completed with results posted in …