Corneal Ulcer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Fluorometholone Study [Phase 2]
A Phase 2 fluorometholone trial for bacterial keratitis and corneal ulcer is not yet recruiting.
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CLINICAL_TRIALS withdrawal · 2026-02-27Clinical Trial Update: Diagnosing Corneal Infection
A clinical trial investigating diagnostic approaches for corneal ulcers has been withdrawn by the sponsor.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis [NA]
A clinical trial is evaluating intrastromal moxifloxacin as an adjunctive therapy for recalcitrant bacterial keratitis. The study is current…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Follow-up Compliance for Corneal Ulcer Patients With SMS Reminder [NA]
An update on a clinical trial evaluating SMS reminders to improve follow-up compliance for corneal ulcer patients; the study is not yet recr…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells [Phase 2]
A Phase 2 trial is evaluating the efficacy of locally delivered allogeneic mesenchymal stromal cells for corneal ulcers. The study is curren…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A [Phase 3]
An ongoing Phase 3 clinical trial is evaluating the combination of natamycin and cyclosporine A for fungal keratitis and corneal ulcers.
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FDA approval · 2025-04-07FDA Approved: TOBRAMYCIN AND DEXAMETHASONE — Supplemental Application (Sandoz Inc)
Supplemental FDA approval for tobramycin and dexamethasone (Sandoz) as an ophthalmic combination product.
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CLINICAL_TRIALS research · 2025-04-07Clinical Trial Update: Village Integrated Eye Workers Trial [NA]
The Village Integrated Eye Workers trial, sponsored by the University of California, San Francisco, investigates corneal ulcers. The study i…
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CLINICAL_TRIALS withdrawal · 2024-12-02Clinical Trial Update: Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis [Phase 4]
The Phase 4 open-label trial evaluating cenegermin (rhNGF) for corneal thickness in neurotrophic keratitis via AS-OCT has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Cross-linking for Corneal Ulcers Treatment Trial [Phase 3]
A Phase 3 trial evaluating cross-linking therapy for corneal ulcers completed, with results posted on 2024-08-27. The sponsor was University…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Studying the Effect of Ethanol Applied on the Corneal Surface During PRK Surgery.
A clinical trial assessed applying ethanol on the corneal surface during PRK surgery; the study has completed.
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcers [Phase 2, Phase 3]
Phase 2/3 trial update evaluating the safety and effectiveness of the PXL Platinum 330 System with riboflavin solution for refractory cornea…
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Previously Untreated Corneal Ulcers [Phase 2, Phase 3]
Clinical trial update on the PXL Platinum 330 System with riboflavin for corneal ulcers, involving Phase 2 and Phase 3, evaluating safety an…
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CLINICAL_TRIALS trial_result · 2022-08-25Clinical Trial Update: Platelet Rich Plasma as a Treatment For Resistant Corneal Ulcers [Phase 4]
Clinical trial update reporting Phase 4 results for platelet-rich plasma as a treatment for resistant corneal ulcers.
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CLINICAL_TRIALS trial_result · 2020-07-30Clinical Trial Update: Treatment of Patients With Inflammatory-dystrophic Diseases of the Cornea Using Autologous Stem Cells [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating autologous stem cell therapy for inflammatory-dystrophic corneal diseases, completed.
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CLINICAL_TRIALS trial_result · 2019-10-07Clinical Trial Update: Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Corneal Ulcer [Phase 3]
Phase 3 trial comparing T4020 to vehicle in chronic neurotrophic keratitis or corneal ulcer completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers [Phase 3]
Phase 3 trial results for a mycotic antimicrobial localized injection in corneal ulcers (fungal keratitis) have been completed. Results were…
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CLINICAL_TRIALS trial_result · 2019-07-29Clinical Trial Update: Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. [Phase 1, Phase 2]
Clinical trial evaluating safety and efficacy of rhNGF in stage 2–3 neurotrophic keratitis completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-10-26Clinical Trial Update: Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar Keratoplasty [NA]
Clinical trial update on safety and effectiveness of a collagen-phosphorylcholine bioengineered cornea for lamellar keratoplasty; study comp…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: The Mycotic Ulcer Treatment Trial II: A Randomized Trial Comparing Oral Voriconazole vs Placebo [Phase 3]
A Phase 3 randomized trial comparing oral voriconazole to placebo for fungal corneal ulcers has completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Fusarium Keratitits in Spain 2012 to 2014
A completed clinical trial conducted in Spain (2012–2014) investigating Fusarium keratitis associated with corneal ulcers.
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcers [Phase 2]
A Phase 2 clinical trial tested povidone-iodine for treating bacterial corneal ulcers; the study status is completed.
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CLINICAL_TRIALS research · 2016-07-07Clinical Trial Update: Topical Anesthesia for Closed PKP vs Retrobulbar Anesthesia for Open-sky PKP [NA]
Clinical trial comparing topical anesthesia for closed penetrating keratoplasty with retrobulbar anesthesia for open-sky PKP, sponsored by W…
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Randomized Double Blinded Study Evaluating CACICOL20 Efficiency Versus Placebo Corneal Chronic Ulcers Healing [NA]
A completed randomized double-blind study comparing CACICOL20 to placebo for healing chronic corneal ulcers.
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CLINICAL_TRIALS trial_result · 2014-11-19Clinical Trial Update: Corneal Lesions in Intensive Care Unit (ICU) Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center Clinical Trial for Proposing Interventions and Evaluating Outcomes of Nursing in the Adult Intensive Care Center [NA]
A completed clinical trial evaluating nursing interventions and outcomes to address corneal lesions in adult ICU patients with keratitis or …