Constipation
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Combined Effects of Whole Body Vibration and Abdominal Binders on Outcome Measures of Constipation in Postnatal Women [NA]
This clinical trial update reports completion of a study evaluating the combined effects of whole body vibration and abdominal binders on co…
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FDA approval · 2025-03-14FDA Approved: LACTULOSE — Original Application (PAI Holdings, LLC dba PAI Pharma)
FDA approved an original application for lactulose as a generic drug, manufactured by PAI Holdings (dba PAI Pharma).
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Foot Reflexology and Abdominal Massage [NA]
A clinical trial (NCT06875349) from Karadeniz Technical University evaluating foot reflexology and abdominal massage for constipation has co…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Exploring the Potential Benefits of Probiotic Yogurt [NA]
A clinical trial sponsored by Wecare Probiotics Co., Ltd. is recruiting to evaluate the potential benefits of probiotic yogurt for chronic c…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Nursing Homes on Constipation and General Comfort [NA]
This clinical trial update reports a completed study evaluating constipation and general comfort in nursing home residents.
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: CMTS4520-Assisted Washed Microbiota Transplantation for Chronic Constipation in Adults [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study of CMTS4520-assisted washed microbiota transplantation for chronic constipation…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: The Effect of Su-Jok Therapy Applied to the Elderly on Constipation Symptoms and Quality of Life [NA]
This update describes a clinical trial evaluating Su-Jok therapy in elderly individuals for constipation symptoms and quality of life, with …
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Investigation of the Additional Effects of Aerobic Exercise Training to Abdominal Massage in Functional Constipation [NA]
Clinical trial evaluating the additional effects of aerobic exercise training to abdominal massage in functional constipation is currently r…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: To Evaluate the Safety and Efficacy of Pediococcus Acidilactici PA53 in Relieving Constipation in Adults [NA]
A clinical trial is evaluating the safety and efficacy of the probiotic Pediococcus acidilactici PA53 for relieving constipation in adults; …
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: GI Symptoms in Infants Fed Goat Milk-based Infant Formula
Clinical trial update on GI symptoms in infants fed goat milk-based infant formula. The study has completed and assessed stool patterns, ski…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy [Phase 4]
Phase 4 trial update evaluating whether a preoperative bowel regimen alters time to first bowel movement after robotic sacral colpopexy; the…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress
Completed clinical trial investigating whether improving gastrointestinal symptoms impacts autism symptoms and oxidative stress, sponsored b…
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CLINICAL_TRIALS other · 2024-12-18Clinical Trial Update: Xuanhuang Runtong Tablet in the Treatment of Constipation (Yin-deficiency Type) [Phase 3]
Phase 3 trial of Xuanhuang Runtong Tablet for Yin-deficiency constipation is not yet recruiting, sponsored by Beijing Hospital of Traditiona…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Efficacy and Tolerability of ABB I5 Prebiotic and ABB C22 Postbiotics for the Management of Constipation and Gastrointestinal Well-being: a Pilot Trial [EARLY_Phase 1]
A Phase 1 pilot trial update evaluating the efficacy and tolerability of ABB I5 Prebiotic and ABB C22 Postbiotics for constipation and overa…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Effect of Agave Inulin on Constipation and Quality of Life in Peritoneal Dialysis Patients. [NA]
A clinical trial evaluating whether agave-derived inulin improves constipation and quality of life in patients on peritoneal dialysis, curre…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes [NA]
A completed University of Miami trial evaluated whether respiratory muscle training combined with patient education improves outcomes in chr…
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FDA approval · 2024-12-13FDA Approved: LACTULOSE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a generic lactulose product from Sun Pharmaceutical Industries as an Original Application (ANDA 218858).
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Effect of Acupressure in The Management of Postmenopausal Constipation [NA]
A clinical trial update on using acupressure to manage constipation in postmenopausal individuals; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: A Study to Assess Different Diagnostic Criteria of Chronic Constipation in Asia
A completed clinical trial sponsored by Janssen evaluating different diagnostic criteria for chronic constipation in Asia.
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Effect of L. Paracasei Strain Shirota on Constipation in Healthy US Adults [NA]
A completed clinical trial assessed the impact of the probiotic Lactobacillus paracasei Shirota on constipation in healthy U.S. adults.
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation [Phase 2]
Phase 2 dose‑response study evaluating the efficacy and safety of ASP0456 in chronic constipation has completed.
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation [Phase 3]
This update reports the completion of a Phase 3 trial evaluating oral dosing of ASP0456 in patients with chronic constipation.
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FDA approval · 2024-10-18FDA Approved: SODIUM SULFATE, POTASSIUM SULFATE AND MAGNESIUM SULFATE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' original application for a generic product containing sodium sulfate, potassium sulfate and magnesium s…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)
This is a completed post-marketing surveillance study evaluating the safety of Linaclotide tablets in patients with chronic constipation and…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Effectiveness of Bacillus Spore Probiotics in Reducing Constipation, Anorexia, and Slow Weight Gain in Children [NA]
This completed clinical trial update assesses the effectiveness of a Bacillus spore probiotic in reducing constipation, anorexia (loss of ap…