Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: The Effects of TTNS, TTNS Combined With PHUS, and Conventional Therapy With PHUS in the Treatment of PFC. [NA]
A clinical trial update assessing TTNS, TTNS with PHUS, and conventional PHUS therapy for constipation is currently recruiting at Hadassah M…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Prevalence of Functional Lower Urinary Tract Voiding Dysfunction in School-Aged Children
This clinical trial update assesses the prevalence of functional lower urinary tract voiding dysfunction in school-aged children.
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CLINICAL_TRIALS withdrawal · 2025-07-14Clinical Trial Update: Do Probiotics Improve Recovery From Acute Constipation in Kids? [NA]
A clinical trial evaluating whether probiotics improve recovery from acute constipation in children was withdrawn.
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial) [Phase 2]
Phase 2 ACCORD trial evaluating the safety and efficacy of a 5-HT4 receptor agonist for chronic constipation has completed.
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen [Phase 4]
Phase 4 clinical trial evaluating changes in the fecal microbiome after antegrade continence enema placement and a bowel flush regimen for c…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Fecal Microbiota Transplantation Via Oral Capsule for Treating Refractory Constipation in Parkinson's Disease [NA]
A completed clinical trial evaluated fecal microbiota transplantation delivered via an oral capsule to treat refractory constipation in Park…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic Sclerosis [Phase 2]
Phase 2 clinical trial investigating fecal microbiota transplantation to treat constipation and significant bloating in patients with system…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis [NA]
This clinical trial sponsored by The University of Texas Health Science Center, Houston is investigating the pathophysiological mechanisms o…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Effectiveness of Self-Administered Acupressure Intervention in Managing Constipation of Adult Psychiatric In-Patient [NA]
A clinical trial evaluating self-administered acupressure to manage constipation in adult psychiatric in-patients. The study is currently re…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Effectiveness of Self-administered Acupressure Intervention in Managing Constipation of Adult Psychiatric Out-patient [NA]
A planned clinical trial is evaluating self-administered acupressure to manage constipation in adult psychiatric outpatients; the study is n…
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FDA approval · 2025-06-24FDA Approved: PRUCALOPRIDE — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' prucalopride (ANDA 218847) as a generic product for the treatment of chronic constipation in adults.
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Fluoxetine for Refractory Constipation [NA]
A completed clinical trial evaluated fluoxetine for refractory constipation.
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Probiotic Intervention for Occasional Constipation [NA]
A completed clinical trial from Probi AB evaluated a probiotic intervention for occasional constipation and gut function.
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Chronic Constipation
ProgenaBiome's pilot clinical trial investigating the role of gut flora in chronic constipation has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Effect to Linaclotide on Colonic Motility [Phase 4]
Phase 4 trial assessing the effect of linaclotide on colonic motility in chronic constipation has completed.
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Effectiveness of Electromagnetic Field Therapy in Chronic Constipation [NA]
A completed clinical trial evaluating electromagnetic field therapy for chronic constipation; the snippet does not provide any outcome resul…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms
A prospective multicentre real-world study is evaluating the efficacy of Danning Tablets for digestive symptoms, with recruitment ongoing.
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Effect of Pre-Surgery Constipation Podcast: A RCT [NA]
This clinical trial entry describes a randomized controlled trial to evaluate whether a pre-surgery constipation podcast affects outcomes in…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Effects of Psyllium on Constipation in Schizo-phrenic: A Randomized Controlled Crossover Trial [NA]
This clinical trial investigates whether psyllium improves constipation in people with schizophrenia using a randomized controlled crossover…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Pre-biotics and Probiotics for Constipation in Parkinson's Disease [NA]
This completed clinical trial evaluated prebiotics and probiotics for constipation in Parkinson's disease.
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Spinal Stabilization Exercise Training in Women With Chronic Constipation [NA]
Clinical trial update for spinal stabilization exercise training in women with chronic constipation; the study is currently not yet recruiti…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair [NA]
This completed clinical trial examined whether defecation posture affects the ease of the first bowel movement after posterior repair for pe…
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EMA approval · 2025-04-11EMA Authorised: Moventig (naloxegol oxalate) — Grunenthal GmbH
EMA authorised Moventig (naloxegol oxalate) from Grunenthal GmbH for the treatment of constipation, including opioid-induced constipation. T…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: CMTS4520 for Chronic Constipation in Adults [Phase 1, Phase 2]
CMTS4520 is being studied for chronic constipation in adults in Phase 1/Phase 2, with recruitment not yet started.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation [Phase 2, Phase 3]
This document reports a clinical trial comparing Actazin to polyethylene glycol 3350 for maintenance therapy in pediatric constipation, with…