Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-09-07Clinical Trial Update: Effect of the Consumption of a Cheese Enriched With Probiotic Organisms in Improving Symptoms of Constipation [NA]
Completed clinical trial evaluating cheese enriched with probiotic organisms for improvement of constipation symptoms.
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic Constipation [Phase 3]
This is an update on a Phase 3 comparator trial comparing polyethylene glycol 3350 to prucalopride in females with chronic constipation; the…
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Prucalopride Subjects With Renal Impairment [Phase 1]
This update reports the completion of a Phase 1 trial evaluating prucalopride in individuals with renal impairment for constipation.
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Single Dose Pharmacokinetics of Prucalopride in Paediatric Subjects, With Functional Faecal Retention [Phase 1]
This Phase 1 report summarizes the single-dose pharmacokinetics of prucalopride in pediatric subjects with functional faecal retention.
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CLINICAL_TRIALS trial_result · 2012-08-22Clinical Trial Update: Prucalopride in Paediatric Subjects, With Functional Faecal Retention [Phase 1]
Phase 1 trial of prucalopride in paediatric subjects with functional faecal retention has completed.
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation [Phase 4]
A Phase 4 clinical trial evaluating the effects of probiotics on intestinal bacterial populations and immune modulation has completed.
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FDA approval · 2012-06-13FDA Approved: PEG-3350, SODIUM SULFATE, SODIUM CHLORIDE, POTASSIUM CHLORIDE, SODIUM ASCORBATE AND ASCORBIC ACID — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approves Teva's supplemental application for a PEG-3350-based laxative formulation containing electrolytes and ascorbate/ascorbic acid, …
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CLINICAL_TRIALS trial_result · 2012-05-15Clinical Trial Update: Lubiprostone as a Treatment for Constipation in Parkinson's Disease [NA]
A terminated clinical trial examined lubiprostone for constipation in people with Parkinson's disease; results were posted in May 2012.
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CLINICAL_TRIALS trial_result · 2012-05-07Clinical Trial Update: Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children [Phase 4]
Phase 4 trial update reporting the efficacy and tolerability of a polyethylene glycol laxative used alone for fecal impaction and chronic co…
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CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: Efficacy and Safety of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain [Phase 2, Phase 3]
Clinical trial update on tegaserod for opioid-induced constipation in adults with non-cancer pain; the Phase 2/3 study was terminated.
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CLINICAL_TRIALS trial_result · 2012-04-19Clinical Trial Update: Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective [Phase 2]
Phase 2 trial shows Itopride as an adjuvant for bowel preparation is effective in patients with chronic constipation.
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CLINICAL_TRIALS trial_result · 2012-02-16Clinical Trial Update: Biofeedback and Cortical Excitability [NA]
The study NCT00653887 evaluating biofeedback and cortical excitability has been terminated. The listed conditions include incontinence and c…
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CLINICAL_TRIALS trial_result · 2012-02-15Clinical Trial Update: Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain [Phase 2, Phase 3]
A completed Phase 2/Phase 3 study evaluating the hydromorphone–naloxone fixed-dose ratio for pain management; constipation is listed as a co…
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CLINICAL_TRIALS trial_result · 2012-02-06Clinical Trial Update: Investigation of KLYX in Patients With Constipation [Phase 2]
A Phase 2 trial evaluating KLYX for constipation has completed, as reported by sponsor Ferring Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2012-02-01Clinical Trial Update: The Intestinal Function in People With Prader-Willi Syndrome
This document reports the completion of a clinical trial assessing intestinal function in individuals with Prader-Willi syndrome.
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CLINICAL_TRIALS trial_result · 2012-01-31Clinical Trial Update: Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects [NA]
A completed clinical trial evaluated the efficacy of a Yakult probiotic product on bowel habits in healthy subjects. Constipation was the co…
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FDA approval · 2012-01-25FDA Approved: ENULOSE — Original Application (Actavis Pharma, Inc.)
FDA approved the original ANDA for Enulose (lactulose) by Actavis Pharma, establishing a generic lactulose product.
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FDA approval · 2012-01-25FDA Approved: CONSTULOSE — Original Application (Actavis Pharma, Inc.)
FDA approved Actavis Pharma, Inc.'s CONSTULOSE as an original generic application for lactulose. Lactulose is used as a laxative for constip…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery [Phase 2, Phase 3]
The study assessed SennaS for preventing postoperative constipation after urogynecologic surgery in Phase 2 and Phase 3 cohorts; the trial s…
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FDA approval · 2011-12-30FDA Approved: MONOBASIC SODIUM PHOSPHATE AND DIBASIC SODIUM PHOSPHATE — Original Application (Lupin Pharmaceuticals,Inc.)
The FDA approved Lupin Pharmaceuticals' generic combination of monobasic and dibasic sodium phosphate via an original ANDA. The product is a…
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CLINICAL_TRIALS research · 2011-11-17Clinical Trial Update: Coffee Against Obstipation in Intensive Care Treatment [NA]
An ongoing clinical trial at University Hospital Heidelberg is evaluating coffee as a treatment for constipation in intensive care patients;…
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CLINICAL_TRIALS trial_result · 2011-09-27Clinical Trial Update: A Preference Study Comparing Kristalose® and Liquid Lactulose [Phase 4]
Phase 4 trial update comparing Kristalose and Liquid Lactulose for constipation; the study is completed and results were posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-09-26Clinical Trial Update: Fiber Formula Study Among Radiation Oncology Patients
A completed Mayo Clinic clinical trial evaluated a fiber formula for constipation in patients receiving radiation therapy.
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: Effects of Cultura Yoghurt in Relation to Transit Time and Digestive Discomfort in Healthy Women and Men [NA]
A completed clinical trial evaluating whether Cultura Yoghurt influences bowel transit time and digestive discomfort in healthy adults with …
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CLINICAL_TRIALS trial_result · 2011-08-23Clinical Trial Update: Efficacy and Safety of TJ-100 in the Treatment of Chronic Constipation [NA]
A completed clinical trial evaluating the efficacy and safety of TJ-100 in the treatment of chronic constipation.