Constipation
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CLINICAL_TRIALS trial_result · 2013-03-29Clinical Trial Update: Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment. [Phase 3]
A Phase 3 clinical trial evaluating Cassia fistula and Senna alexandrina Miller for chronic functional constipation has completed.
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CLINICAL_TRIALS trial_result · 2013-03-11Clinical Trial Update: Dose-Finding Trial of Polyethylene Glycol 3350 Laxative Plus Electrolytes for the Treatment of Constipation (Protocol P07515) [Phase 2]
Phase 2 dose-finding trial of polyethylene glycol 3350 laxative plus electrolytes for constipation completed; results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation [Phase 2]
Dose-range-finding Phase 2 trial results for oral linaclotide acetate in adults with chronic constipation; the study has completed and resul…
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CLINICAL_TRIALS trial_result · 2013-02-21Clinical Trial Update: Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation [NA]
This clinical trial compared lubiprostone (Amitiza) to standard care for opioid-induced constipation after surgery in an inpatient rehabilit…
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CLINICAL_TRIALS trial_result · 2013-02-11Clinical Trial Update: The PRIDE Study Probiotics on Regulation and Improving Digestive hEalth [Phase 3]
Phase 3 trial of PRIDE Study Probiotics evaluating regulation and improvement of digestive health has completed.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: A Pilot Study of a New MiraLax® Dose Formulation For Use in Constipated Children [Phase 4]
A Phase 4 pilot trial evaluated a new MiraLax dose formulation for treating constipation in children and has completed.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: PolyethyleneGlycol3350 Laxative vs Placebo in Constipated Children [Phase 4]
A Phase 4 trial comparing polyethylene glycol 3350 laxative to placebo in constipated children has completed.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Extended Use of Polyethyleneglycol3350 Laxative in Constipated Patients [Phase 4]
Phase 4 study evaluating extended use of polyethylene glycol 3350 laxative in constipated patients is completed.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Polyethyleneglycol3350 vs Tegaserod in Treatment of Patients With Chronic Constipation [Phase 4]
Phase 4 clinical trial comparing polyethylene glycol 3350 with tegaserod in chronic constipation has completed.
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: An Open Label Study of Chronic Polyethyleneglycol3350 Use in Constipated Patients [Phase 4]
Completed Phase 4 open-label study evaluating chronic use of polyethylene glycol 3350 for constipation. The study was sponsored by Braintree…
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Comparison of PolyethyleneGlycol and Placebo for Relief of Constipation From Constipating Medications [Phase 4]
Phase 4 trial comparing polyethylene glycol to placebo for relief of constipation caused by constipating medications; the study has complete…
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FDA approval · 2013-02-06FDA Approved: PURELAX — Supplemental Application (CVS Pharmacy)
The FDA approved a supplemental application for PURELAX (polyethylene glycol 3350) filed by CVS Pharmacy.
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FDA label_change · 2013-02-05FDA Approved: WINCO — Supplemental Application (WINCO FOODS)
FDA approved a supplemental application for WINCO polyethylene glycol 3350 from WINCO Foods. The action updates the product's labeling (and …
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CLINICAL_TRIALS trial_result · 2013-01-30Clinical Trial Update: Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation [Phase 3]
Phase III randomized, double-blind, placebo-controlled trial of linaclotide in patients with chronic constipation completed, with results po…
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CLINICAL_TRIALS trial_result · 2013-01-30Clinical Trial Update: Trial of Linaclotide in Patients With Chronic Constipation [Phase 3]
This document reports the completion and posting of results for a Phase 3 trial of linaclotide in chronic constipation. Results were posted …
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CLINICAL_TRIALS trial_result · 2013-01-15Clinical Trial Update: Reflexology for Chronic Constipation [Phase 2]
A Phase 2 clinical trial is investigating reflexology for chronic constipation. The current trial status is UNKNOWN.
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FDA approval · 2012-12-28FDA Approved: WINCO — Original Application (WINCO FOODS)
FDA approves WINCO as an original Abbreviated New Drug Application for polyethylene glycol 3350 (a laxative) to be manufactured by WINCO FOO…
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Use of Pyridostigmine for Constipation in Diabetics [Phase 1, Phase 2]
Clinical trial update showing completed Phase 1/Phase 2 studies of pyridostigmine for constipation in diabetics, with results posted in 2012…
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CLINICAL_TRIALS research · 2012-11-28Clinical Trial Update: Efficacy and Safety of Prunus Mume Extract on Improvement of Constipation [Phase 2, Phase 3]
Clinical trial update evaluating the efficacy and safety of Prunus mume extract for constipation in Phase 2 and Phase 3 studies.
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: Diurnal Variation in Rectal Diameter
A completed clinical trial investigated diurnal variation in rectal diameter in individuals with constipation.
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System [NA]
A completed clinical trial evaluating Inner Mongolia Yili's Changqing Pro-ABB yoghurt for improving gastrointestinal symptoms. The study foc…
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Physiotherapeutic Intervention in Children With Chronic Functional Constipation [NA]
A completed clinical trial assessed a physiotherapeutic intervention for children with chronic constipation; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-10-15Clinical Trial Update: Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System [NA]
Completed clinical study evaluating Yili Mei Yi Tian Active Lactobacillus Drink for improving immunity and digestive health. The trial asses…
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: BLI801 Laxative in Constipated Adults [Phase 2]
Phase 2 study of BLI801 laxative in adults with constipation has completed.
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation [Phase 3]
A Phase 3 clinical trial evaluating a docusate sodium and sorbitol rectal solution for constipation has completed enrollment and status is r…