Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Fibers and Gut Health [NA]
Nestlé-sponsored clinical trial evaluating dietary fibers for constipation has completed.
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Probiotics and Gut Health [NA]
Nestlé-sponsored clinical trial evaluating probiotics for constipation has completed.
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FDA approval · 2015-10-29FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
FDA approved a supplemental application for MIRALAX (polyethylene glycol 3350) submitted by Bayer HealthCare LLC.
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CLINICAL_TRIALS research · 2015-10-16Clinical Trial Update: The Function of Gastrointestinal Tract During Pregnancy
A completed ClinicalTrials.gov study from Kuopio University Hospital evaluated the function of the gastrointestinal tract during pregnancy, …
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery [Phase 4]
This clinical trial update notes the completion of a Phase 4 study evaluating opioid-induced bowel dysfunction, focusing on constipation, in…
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Predictors of Constipation in Healthy Children
A completed clinical trial from University of Wisconsin–Madison investigates predictors of constipation in healthy children.
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Efficacy of Oxycodone/Naloxone(OXN), Versus Oxycodone (OXY), for the Reduction of Intensity of Opioid-induced Constipation in Pain Patients [Phase 3]
A Phase 3 trial comparing oxycodone/naloxone to oxycodone for reducing opioid-induced constipation in pain patients has been terminated.
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FDA approval · 2015-09-24FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
The FDA approved a supplemental application for MIRALAX (polyethylene glycol 3350) by Bayer HealthCare LLC.
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation [NA]
A completed clinical trial evaluating whether consuming Orafti® Inulin affects bowel motor function in people with constipation.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain [Phase 3]
Phase 3 trial update of alvimopan (Entereg) for opioid-induced constipation in patients with persistent non-cancer pain; the study has compl…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain [Phase 3]
Phase 3 clinical trial evaluating treatment for opioid-induced constipation in adults with persistent non-cancer pain has completed.
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Effects of Self-administered Acupressure in Psychiatric Patients With Constipation [Phase 1, Phase 2]
This is a completed Phase 1/Phase 2 clinical trial evaluating self-administered acupressure for constipation in psychiatric patients.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation [Phase 4]
Phase 4 trial update comparing Transipeg 2.95 g and Forlax Junior 4 g for constipation in children.
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Enteral Naloxone Versus a Traditional Bowel Regimen for the Prevention of Opioid Induced Constipation in Trauma Patients [Phase 4]
Phase 4 trial comparing enteral naloxone to a traditional bowel regimen to prevent opioid-induced constipation in trauma patients; the study…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Efficacy of Sacral Nerve Modulation in Severe Refractory Constipation [Phase 2]
Phase 2 trial update evaluating the efficacy of sacral nerve modulation for severe refractory constipation. The study by University Hospital…
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CLINICAL_TRIALS withdrawal · 2015-07-16Clinical Trial Update: Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005) [Phase 3]
Bayer’s Phase 3 trial MK-8114-005 evaluating polyethylene glycol 3350 (PEG 3350) for relief of constipation has been withdrawn.
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FDA approval · 2015-07-14FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
FDA approved a supplemental application for Miralax (polyethylene glycol 3350) from Bayer HealthCare LLC.
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation [Phase 2]
The Phase 2 feasibility trial of oral naloxone for methadone-induced constipation has completed. The study was sponsored by the Centre for A…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Functional Ingredients: Effect in Gastrointestinal System [NA]
A completed clinical trial evaluating the effect of functional ingredients on the gastrointestinal system in individuals who are overweight/…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Efficacy and Safety of YKP10811 in Subjects With Irritable Bowel Syndrome With Constipation [Phase 2]
Phase 2 trial of YKP10811 in irritable bowel syndrome with constipation has completed, reporting efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain [Phase 2]
Phase 2 clinical trial evaluating ADL5945 for opioid-induced constipation in adults on chronic opioid therapy; trial completed with results …
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CLINICAL_TRIALS trial_result · 2015-05-22Clinical Trial Update: A Colonic Tube to Improve Bowel Function in Spinal Cord Injury [NA]
Completed clinical trial evaluating a colonic tube to improve bowel function in people with spinal cord injury; results relate to constipati…
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: Drink Milk Consumption Benefits With Culture Probiotic in the Treatment of Constipation [NA]
This entry reports a completed clinical trial evaluating milk consumption fortified with a probiotic culture for the treatment of constipati…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation. [Phase 2]
This entry notes the completion of a Phase 2 clinical trial evaluating a probiotic supplement for constipation, focusing on colonic transit …
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Effect of Mosapride on Gut Transit in Patients With Chronic Constipation or Constipated Irritable Bowel Syndrome and Healthy Subjects [Phase 4]
This Phase 4 clinical trial update describes a study evaluating the effect of mosapride on gut transit in patients with chronic constipation…