Constipation
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-08-24FDA Approved: POLYETHYLENE GLYCOL 3350 — Original Application (Major Pharmaceuticals)
FDA approved the original ANDA for polyethylene glycol 3350 (INSTALAX) by Major Pharmaceuticals, a laxative used to treat constipation.
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation [Phase 4]
Phase 4 trial update on safety and efficacy of lubiprostone in pediatric patients with constipation.
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Fiber and Water Improve Bowel Habit in Humans [Phase 1, Phase 2]
Phase 1 and Phase 2 trials indicate that increasing dietary fiber and water intake may improve bowel habits in humans.
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CLINICAL_TRIALS trial_result · 2016-07-19Clinical Trial Update: Use of Drugs and Constipation in Nursing Homes
This clinical trial update summarizes a study on the use of medications and constipation outcomes in nursing homes; the trial NCT00849628 ha…
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CLINICAL_TRIALS research · 2016-06-21Clinical Trial Update: Colonic Motility in Constipation and Aging: A Study With a New 3D Transit System
A clinical trial from the University of Aarhus is investigating how aging affects colonic motility in constipation using a new 3D transit sy…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: The Efficacy of Individualised Homeopathic Treatment on Constipation [Phase 2]
A completed Phase 2 trial evaluating the efficacy of individualized homeopathic treatment for constipation. The update notes the trial's com…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Effectiveness of Standing Frame on Constipation in Children With Cerebral Palsy
A completed clinical trial update assessing the effectiveness of a standing frame on constipation in children with cerebral palsy.
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CLINICAL_TRIALS research · 2016-05-13Clinical Trial Update: Defecation Postures for Functional Consumption [NA]
Clinical trial NCT02772692 investigates defecation postures for functional constipation, sponsored by Air Force Military Medical University …
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating [Phase 3]
Phase 3 trial evaluating safety and efficacy of linaclotide in chronic constipation with abdominal bloating completed; results posted in 201…
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: Relationship Between Constipation and Inguinal Hernia
A completed clinical trial investigating the relationship between constipation and inguinal hernia.
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Cognitive Behaviour Therapy for Patients With IBS [NA]
A completed clinical trial evaluating cognitive-behavioral therapy for irritable bowel syndrome, including constipation and related symptoms…
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: The Effectiveness of Lubiprostone in Constipated Diabetics [Phase 4]
A Phase 4 clinical trial evaluating lubiprostone for constipation in diabetic patients has completed and posted results. The study assessed …
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Effect of Tegaserod on Orocecal Transit in Elderly Chronic Constipation Patients [Phase 4]
Phase 4 trial evaluating tegaserod's effect on orocecal transit in elderly adults with chronic constipation. The study was terminated.
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CLINICAL_TRIALS withdrawal · 2016-03-04Clinical Trial Update: The Effects of Tegaserod vs. Placebo on Whole Gut Transit Time in Patients With Chronic Constipation and Dyspepsia [Phase 4]
A Phase 4 trial comparing tegaserod to placebo for whole gut transit time in chronic constipation and dyspepsia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Preference of Tegaserod vs. PEG 3350 in Patients With Constipation [Phase 4]
Phase 4 trial comparing tegaserod with polyethylene glycol 3350 for constipation has completed.
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CLINICAL_TRIALS withdrawal · 2016-02-03Clinical Trial Update: Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation [NA]
A clinical trial evaluating functional magnetic stimulation to enhance gastrointestinal motility in chronic constipation has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Methylnaltrexone for Opioid-induced Constipation in Cancer Patients [Phase 2]
Phase 2 clinical trial evaluating methylnaltrexone for opioid-induced constipation in cancer patients has completed and posted results.
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CLINICAL_TRIALS research · 2016-01-15Clinical Trial Update: Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform [NA]
Clinical trial update describing the development and validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) platform to…
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FDA approval · 2016-01-12FDA Approved: PURELAX — Supplemental Application (CVS Pharmacy)
FDA approved a supplemental application for PureLax (polyethylene glycol 3350) submitted by CVS Pharmacy. It is a laxative approved for the …
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: Effect of Octreotide on the Colonic Motility in Pediatric Patients [Phase 4]
Phase 4 pediatric trial evaluating the effect of octreotide on colonic motility has completed and results were posted on 2015-12-21.
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FDA approval · 2015-12-15FDA Approved: POLYETHYLENE GLYCOL 3350 — Original Application (SKY Packaging)
FDA approved an Original Application for polyethylene glycol 3350 from SKY Packaging, making it an approved generic laxative. The product is…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Lubiprostone in Patients With Multiple Sclerosis Associated Constipation [Phase 4]
Phase 4 trial evaluating lubiprostone for constipation in patients with multiple sclerosis has completed, with results posted in December 20…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury
A completed clinical trial from the University of Aarhus examined gastrointestinal transit time in patients with severe acquired brain injur…
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CLINICAL_TRIALS withdrawal · 2015-12-02Clinical Trial Update: A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chronic Constipation
This entry indicates that a post-marketing surveillance study evaluating the safety and effectiveness of prucalopride for chronic constipati…
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FDA label_change · 2015-11-12FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
FDA approved a supplemental application for Miralax (polyethylene glycol 3350) filed by Bayer HealthCare LLC. The action updates the labelin…