Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation. [Phase 1]
Phase 1 trial evaluating the effect of lubiprostone on methanogenesis and bowel function in chronic constipation has completed with results …
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CLINICAL_TRIALS trial_result · 2019-01-11Clinical Trial Update: Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions [Phase 2]
Phase 2 trial results examining how an alpha-1 antagonist, stress, and relaxation impact anorectal function in constipation.
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CLINICAL_TRIALS trial_result · 2018-12-26Clinical Trial Update: Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation [Phase 4]
Phase 4 clinical trial updating the use of synbiotic, prebiotics, and probiotics in children with cerebral palsy and chronic constipation.
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FDA approval · 2018-12-21FDA Approved: POLYETHYLENE GLYCOL 3350 AND ELECTROLYTES - UNFLAVORED — Original Application (Strides Pharma Science Limited)
FDA approves Strides Pharma Science Limited's polyethylene glycol 3350 with electrolytes - unflavored as an original generic application.
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CLINICAL_TRIALS trial_result · 2018-12-13Clinical Trial Update: Naloxone in Treating Constipation in Patients Who Are Receiving Opioids for Chronic Pain [Phase 3]
Phase 3 clinical trial investigating naloxone for treating constipation in adults receiving opioids for chronic pain.
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FDA approval · 2018-11-23FDA Approved: LACTULOSE — Original Application (Chartwell RX, LLC)
FDA approves Lactulose from Chartwell RX, LLC under ANDA209517; a generic formulation indicated for constipation and hepatic encephalopathy.
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating spinal cord stimulation for pain relief in irritable bowel syndrome. The study includes IBS …
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy [Phase 3]
Phase 3 clinical trial assessing improvement in constipation symptoms in patients on around-the-clock opioid pain therapy; study completed.
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CLINICAL_TRIALS trial_result · 2018-10-19Clinical Trial Update: Polyethylene Glycol (PEG) Versus Sennosides Study in Opioid-Induced Constipation in Cancer Patients [Phase 4]
Phase 4 trial comparing polyethylene glycol to sennosides for opioid-induced constipation in cancer patients; study terminated with results …
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FDA approval · 2018-10-12FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
FDA approved a supplemental application for MiraLAX (polyethylene glycol 3350) submitted by Bayer HealthCare LLC.
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CLINICAL_TRIALS trial_result · 2018-09-28Clinical Trial Update: A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation [Phase 2]
A Phase 2 pilot study evaluating the laxative BLI801 in adults with non-idiopathic constipation has completed.
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CLINICAL_TRIALS trial_result · 2018-08-24Clinical Trial Update: Clinical Effects of Soluble Dietary Fiber Supplementation [Phase 3]
Phase 3 clinical trial assessing soluble dietary fiber supplementation for hypomotility and constipation; trial completed.
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Lubiprostone for the Treatment of Chronic Idiopathic Constipation [Phase 3]
Phase 3 trial update for lubiprostone in chronic idiopathic constipation has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-08-08Clinical Trial Update: Clinical Trial on Palliative Cancer Patients With Constipation [Phase 2]
Phase 2 clinical trial update on palliative cancer patients with constipation has been completed.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Sierra High Definition Ano-Rectal Manometry
The Sierra High Definition Ano-Rectal Manometry trial has completed.
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CLINICAL_TRIALS research · 2018-07-23Clinical Trial Update: Investigation of Cortico-Rectal Pathways in Healthy Subjects and Constipated Patients
This document updates a clinical trial investigating cortico-rectal pathways in healthy subjects and constipated patients. The sponsor is Au…
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FDA approval · 2018-06-11FDA Approved: LACTULOSE — Original Application (APOZEAL PHARMACEUTICALS INC)
FDA approved Lactulose under an original application from Apozeal Pharmaceuticals Inc.
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Mechano-physiological Approach to Anorectal Function
This is an update indicating the NCT00219518 trial on a mechano-physiological approach to anorectal function for constipation has been termi…
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FDA approval · 2018-05-04FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
The FDA approved a supplemental application for MIRALAX (polyethylene glycol 3350) from Bayer HealthCare LLC, updating its labeling.
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes [NA]
The document reports completion of a clinical trial evaluating the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) and its effect …
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Efficacy of Vibrating Capsule in Patients With Chronic Constipation [NA]
An update on a clinical study evaluating the efficacy of a vibrating capsule for chronic constipation. The current trial status is unknown.
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FDA approval · 2018-04-24FDA Approved: MIRALAX — Supplemental Application (Bayer HealthCare LLC.)
FDA approved a supplemental application for MIRALAX (polyethylene glycol 3350) from Bayer HealthCare LLC.
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: Randomised Controlled Trial of Efficacy of Resistant Maltodextrins on Reducing Colonic Transit Time [NA]
A completed randomized controlled trial evaluated whether resistant maltodextrins can reduce colonic transit time in individuals with consti…
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: A Study Investigating the Effect of Digesta-Lac in Healthy Adults With Occasional Constipation [Phase 2]
A Phase 2 clinical trial evaluating the effects of Digesta-Lac in healthy adults with occasional constipation has completed.
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FDA approval · 2018-04-09FDA Approved: POLYETHYLENE GLYCOL 3350 — Original Application (Aurobindo Pharma Limited)
FDA approved Aurobindo Pharma Limited's polyethylene glycol 3350 as an original generic application (ANDA 209017), expanding access to a lax…