Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain [Phase 2]
Phase 2 clinical trial evaluating oral MOA-728 for treating opioid-induced bowel dysfunction in adults with chronic non-malignant pain; resu…
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Study Evaluating MOA-728 Oral for the Treatment of OIBD in Subjects With Chronic Non-Malignant Pain [Phase 2]
Phase 2 trial update for MOA-728 oral in chronic non-malignant pain–associated opioid-induced bowel dysfunction (OIBD) completed with result…
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Probiotics-prebiotic Fiber Therapy in Parkinson's Disease Patients With Constipation [Phase 3]
A Phase 3 clinical trial investigating a probiotics-prebiotic fiber therapy for constipation in Parkinson's disease patients has completed.
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CLINICAL_TRIALS trial_result · 2020-06-26Clinical Trial Update: BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults [Phase 3]
A Phase 3 clinical trial evaluating the safety and efficacy of BLI400 laxative in adults with constipation, including chronic idiopathic con…
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CLINICAL_TRIALS trial_result · 2020-06-26Clinical Trial Update: An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults [Phase 3]
Phase 3 open-label study of chronic use of the laxative BLI400 in adults with constipation showed completed status and posted results.
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CLINICAL_TRIALS trial_result · 2020-06-26Clinical Trial Update: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects [Phase 2]
Phase 2 trial evaluating safety and efficacy of BLI400 laxative in constipated adolescents has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence. [Phase 3]
Phase 3 clinical trial update evaluating Forlax treatment in children with chronic constipation, including potential soiling/faecal incontin…
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FDA approval · 2020-04-03FDA Approved: POLYETHYLENE GLYCOL — Supplemental Application (BluePoint Laboratories)
The FDA approved a supplemental application for polyethylene glycol 3350 by BluePoint Laboratories.
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FDA approval · 2020-03-24FDA Approved: LACTULOSE — Supplemental Application (PAI Holdings, LLC dba PAI Pharma)
The FDA approved a supplemental application for lactulose from PAI Holdings (PAI Pharma), updating its labeling and potentially expanding th…
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CLINICAL_TRIALS trial_result · 2020-01-30Clinical Trial Update: Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial [NA]
A completed randomized controlled trial comparing electro-acupuncture with prucalopride for severe chronic constipation; results posted in 2…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Treating Anorectal Dysfunction in MS [Phase 2]
Phase 2 trial update for treating anorectal dysfunction in multiple sclerosis; study terminated with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Study Evaluating the Efficacy and Safety of Subcutaneous Methylnaltrexone (MOA-728) for the Treatment of Opioid-Induced-Constipation [Phase 3]
A Phase 3 clinical trial evaluated the efficacy and safety of subcutaneous methylnaltrexone (MOA-728) for opioid-induced constipation; resul…
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CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain [Phase 2]
Phase 2 trial evaluating oral MOA-728 for opioid-induced bowel dysfunction in chronic non-malignant pain was completed.
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CLINICAL_TRIALS trial_result · 2019-10-18Clinical Trial Update: Study Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced Constipation [Phase 3]
Phase 3 clinical trial update assessing long-term safety of MOA-728 in participants with opioid-induced constipation.
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FDA label_change · 2019-10-11FDA Approved: PURELAX — Supplemental Application (CVS Pharmacy)
FDA approved a supplemental application for PURELAX (polyethylene glycol 3350) submitted by CVS Pharmacy, updating labeling for this product…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients [Phase 4]
A Phase 4 trial evaluating naloxegol for preventing constipation in postoperative spinal surgery patients was terminated; results were poste…
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: Naloxegol in Cancer Opioid-Induced Constipation [Phase 2]
Phase 2 clinical trial update for naloxegol in cancer opioid-induced constipation has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Biomarkers for Intestinal Permeability in Patients With Constipation
Clinical trial update studying biomarkers for intestinal permeability in patients with constipation; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-20Clinical Trial Update: The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation [NA]
Clinical trial update on CSP01 for chronic idiopathic constipation and irritable bowel syndrome with constipation has completed with results…
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Study of Long-term Use of Forlax® in Elderly Patients With Chronic Constipation [Phase 4]
A Phase 4 clinical trial update on long-term use of Forlax in elderly patients with chronic constipation has completed.
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CLINICAL_TRIALS trial_result · 2019-06-17Clinical Trial Update: Effect of Kiwifruit on Gastrointestinal Fluid Distribution and Transit in Healthy Volunteers [NA]
Clinical trial update on the effect of kiwifruit on GI fluid distribution and transit in healthy volunteers; completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation) [Phase 4]
Phase 4 trial evaluating tolerability, safety, and feasibility of naloxegol for opioid-induced constipation in cancer patients; study termin…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Fiber Regimens for Constipation Symptoms [NA]
The clinical trial evaluating fiber regimens for constipation symptoms has completed.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation [Phase 3]
An open-label, long-term safety study evaluating linaclotide in patients with chronic constipation or irritable bowel syndrome with constipa…
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CLINICAL_TRIALS research · 2019-02-07Clinical Trial Update: Fecal Calprotectin Collection Protocol
This clinical trial update outlines the fecal calprotectin collection protocol used in a completed trial sponsored by DiaSorin.