Colorectal Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-29Clinical Trial Update: A Phase II Trial of Weekly Alternating Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Advanced Colorectal Cancer [Phase 2]
Phase II trial evaluating weekly alternating sequential administration of BIBF 1120 and BIBW 2992 in advanced colorectal cancer has complete…
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EMA withdrawal · 2017-11-13EMA Refused: Human IGG1 monoclonal antibody specific for human interleukin-1 alpha XBiotech (human IgG1 monoclonal antibody specific for human interleukin-1 alpha) — XBiotech Germany GmbH
The EMA refused approval for a human IgG1 monoclonal antibody targeting interleukin-1 alpha for colorectal neoplasms, with XBiotech Germany …
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Comparison of Intracorporeal and Extracorporeal Anastomoses for Minimally Invasive Right Colectomy
Completed clinical trial comparing intracorporeal versus extracorporeal anastomoses for minimally invasive right colectomy; the update notes…
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CLINICAL_TRIALS trial_result · 2017-10-06Clinical Trial Update: A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC [Phase 3]
Phase 3 trial comparing second-line FOLFIRI ± bevacizumab versus irinotecan ± bevacizumab in metastatic colorectal cancer; status not disclo…
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CLINICAL_TRIALS research · 2017-10-06Clinical Trial Update: The GEOLynch Cohort Study
The GEOLynch Cohort Study, sponsored by Wageningen University, is currently recruiting to investigate Lynch Syndrome-associated neoplasms.
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Sequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial comparing sequential and concurrent FOLFOXIRI/Bevacizumab regimens versus FOLFOX/Bevacizumab as first-line therapy in metastat…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Motorized Spiral Colonoscopy Trial: A First Feasibility Trial [NA]
The study reports completion of the first feasibility trial of a motorized spiral colonoscope, evaluating safety and feasibility in colonosc…
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CLINICAL_TRIALS trial_result · 2017-07-31Clinical Trial Update: Efficacy of Fecal Immunochemical Test Using Digital Rectal Exam [Phase 1]
A Phase 1 trial evaluating a fecal immunochemical test (FIT) using digital rectal exam was terminated.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1) [Phase 3]
A Phase 3 trial (LUME-Colon 1) comparing nintedanib (BIBF 1120) to placebo in refractory metastatic colorectal cancer has completed and post…
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CLINICAL_TRIALS research · 2017-07-18Clinical Trial Update: Investigating the Use of Fluorescent Lectins to Identify Dysplasia and Cancer During Endoscopy and Surgery [EARLY_Phase 1]
An early-phase Phase 1 clinical trial is investigating the use of fluorescent lectins to identify dysplasia and cancer during endoscopy and …
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CLINICAL_TRIALS research · 2017-06-27Clinical Trial Update: Third Eye Panoramic Device Feasibility Evaluation [NA]
A feasibility evaluation of the Third Eye Panoramic Device for colorectal neoplasms sponsored by Avantis Medical Systems; the study status i…
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: Biodegradable Stenting Anastomoses Versus Double-layer Hand Sutures for Reconstruction in Intestinal Anastomosis [Phase 1]
Clinical trial update comparing biodegradable stenting anastomoses to double-layer hand sutures for reconstruction in intestinal anastomosis…
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CLINICAL_TRIALS withdrawal · 2017-06-19Clinical Trial Update: Evaluation of a New Organization for Collecting Pre-chemotherapy Session Information [NA]
A clinical trial (NCT03191487) investigating collection of pre-chemotherapy session information was withdrawn. Sponsor: Centre Hospitalier U…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Initiation of Colon Cancer Screening in Veterans or "Start Screening Now" [NA]
This clinical trial update notes the initiation of colon cancer screening for veterans under the Start Screening Now program. The entry for …
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Screening for Colorectal Neoplasm in First Degree Relatives of the Affected
A completed clinical trial from the Chinese University of Hong Kong evaluated screening for colorectal neoplasms in first-degree relatives o…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study [NA]
The FIND FLAT colonoscopy study compared narrow-band imaging to standard white-light colonoscopy for detecting flat polyps. The trial has co…
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Computer Aided Diagnosis of Colorectal Neoplasms During Colonoscopic Examination [NA]
This entry notes an ongoing clinical trial evaluating computer-aided diagnosis for colorectal neoplasms during colonoscopy.
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery [Phase 4]
Phase 4 clinical trial update from the University of Illinois College of Medicine at Peoria evaluating multimodal, opioid-sparing perioperat…
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CLINICAL_TRIALS trial_result · 2017-03-08Clinical Trial Update: Clinical Evaluation of Narrow Band Imaging Colonoscope [Phase 4]
A Phase 4 clinical evaluation of a Narrow Band Imaging colonoscope for detecting colorectal neoplasms has been completed, with results poste…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Detection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel Disease
This completed clinical trial evaluated stool DNA testing as a non-invasive method to detect advanced colorectal neoplasia in patients with …
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: The Impact of Warmed Carbon Dioxide Insufflation During Colonoscopy on Polyp Detection [NA]
A terminated clinical trial evaluated whether warmed carbon dioxide insufflation during colonoscopy affects detection of colorectal polyps a…
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EMA withdrawal · 2016-12-22EMA Withdrawn: Capecitabine SUN (capecitabine) — Sun Pharmaceutical Industries Europe B.V.
Capecitabine SUN (capecitabine) has been withdrawn from the European market by Sun Pharmaceutical Industries Europe B.V.
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Concentration of Ertapenem in Colorectal Tissue [Phase 4]
A Phase 4 clinical trial evaluated ertapenem concentration in colorectal tissue in participants with diverticulosis of the colon or colorect…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating an investigational drug to prevent chemotherapy-induced diarrhea in previously untreated metastatic colorectal ca…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: MS Versus NICE for Colorectal Lesions [NA]
A completed clinical trial (NCT02963207) sponsored by Lyell McEwin Hospital evaluated colorectal lesions, including colorectal neoplasms and…