Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: Povidone-iodine vs Saline Solution in Colorectal Surgeries and Its Effects on the Surgical Site Infection [Phase 3]
Phase 3 clinical trial comparing povidone-iodine to saline for preventing surgical site infections in colorectal surgeries is currently recr…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Care Coordination for Complex Cancer Survivors in an Integrated Safety Net System [NA]
A completed clinical trial update assessing care coordination for complex cancer survivors within an integrated safety net system; results p…
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer [Phase 3]
A Phase 3 study evaluating Futuximab/Modotuximab in combination with trifluridine/tipiracil versus trifluridine/tipiracil alone in previousl…
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FDA approval · 2024-03-05FDA Approved: CAPECITABINE — Original Application (BluePoint Laboratories)
The FDA approved the original application for capecitabine by BluePoint Laboratories, enabling a generic version of the cancer drug.
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: A Study of Systemic Chemotherapy With/Without HAI in Patients With Initially Unresectable Colorectal Liver Metastasis [Phase 3]
A Phase 3 trial comparing systemic chemotherapy with or without hepatic arterial infusion (HAI) in patients with initially unresectable colo…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: Intravenous T3011 Given as a Single Agent and in Combination With Other Therapy in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update for intravenous T3011 as a single agent and in combination therapy in advanced solid tumors including hepatocellular c…
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma [Phase 2]
This Phase 2 trial evaluating NIR178 in combination with PDR001 across multiple solid tumors and non-Hodgkin lymphoma was terminated, with r…
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: Dose Finding Study in Colorectal Cancer Patients Receiving 5-FU-based Chemotherapy to Assess the Efficacy of Elsiglutide in the Prevention of Chemotherapy Induced Diarrhea (CID) [Phase 2]
Phase 2 dose-finding trial evaluating elsiglutide to prevent chemotherapy-induced diarrhea in colorectal cancer patients receiving 5-FU-base…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: SGM-101 Tumor Targeted Fluorescence Endoscopy in Rectal Polyps With Suspected T1 Adenocarcinoma or High Grade Dysplasia [Phase 2]
Phase 2 clinical trial update for SGM-101 tumor-targeted fluorescence endoscopy in rectal polyps with suspected T1 adenocarcinoma or high-gr…
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Efficacy and the Safety of Regorafenib in Patients Aged More Than 70 Years With a Metastatic Colorectal Adenocarcinoma . [Phase 2]
Phase 2 trial updating efficacy and safety of regorafenib in patients over 70 with metastatic colorectal adenocarcinoma; results posted afte…
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases [Phase 3]
Phase 3 trial evaluating second and third look laparoscopy in pT4 colon cancer patients for early detection of peritoneal metastases; status…
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Aflibercept and 5-FU vs. FOLFOX as 1st Line Treatment for Elderly or Frail Elderly Patients With Met. Colorectal Cancer [Phase 2]
Phase 2 trial comparing aflibercept with 5-FU versus FOLFOX as first-line therapy in elderly or frail elderly patients with metastatic color…
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: The Efficacy and Safety of Lcaritin Combined With Bevacizumab and FOLFIRI in Treatment of Liver Metastases From Colorectal Cancer [Phase 4]
Phase 4 trial update evaluating Lcaritin with Bevacizumab and FOLFIRI for liver metastases from colorectal cancer; efficacy and safety data …
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Metastatic Colorectal Cancer [Phase 2, Phase 3]
A clinical trial update for evaluating IAH0968 in combination with CAPEOX in HER2-positive metastatic colorectal cancer (Phase 2/Phase 3). S…
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CLINICAL_TRIALS trial_result · 2024-02-16Clinical Trial Update: Neoadjuvant Tisleizumab(BGB-A317) for dMMR/MSI-H Non-late Stage CRC Patients Before Surgery [Phase 2]
Phase 2 neoadjuvant trial evaluating tisleizumab (BGB-A317) for dMMR/MSI-H colorectal cancer patients prior to surgery; current status is un…
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations [Phase 2]
A Phase 2 clinical trial update shows results for trastuzumab deruxtecan (Enhertu) in solid tumors with HER2 activating mutations; the study…
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: PRevention Using EPA Against coloREctal Cancer [Phase 1, Phase 2]
Update on a Phase 1/Phase 2 trial evaluating eicosapentaenoic acid (EPA) for prevention of colorectal cancer and colorectal adenoma; results…
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial S1613 evaluated trastuzumab plus pertuzumab versus cetuximab plus irinotecan in locally advanced or metastatic HER2-amplified …
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Toripalimab,Celecoxib and Regorafenib in the Treatment of Refractory Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating toripalimab combined with celecoxib and regorafenib for refractory advanced colorectal cancer with liver m…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer [Phase 3]
Phase 3 clinical trial evaluating metformin administration in stage IV colorectal cancer to assess its impact on clinical outcomes has compl…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery [Phase 2, Phase 3]
A randomized trial comparing chemotherapy alone versus chemotherapy plus radiation therapy in locally advanced rectal cancer undergoing surg…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers [Phase 3]
Phase 3 clinical trial update involving aspirin for Dukes C and high-risk Dukes B colorectal cancer; status is currently unknown.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Phase II Randomized Study Evaluating the Efficacy of Panitumumab (VEctibix ) and Trifluridine-Tipiracil (LOnsurf) in Pretreated RAS Wild Type Metastatic Colorectal Cancer Patients: the VELO Trial [Phase 2]
Phase II randomized study evaluating panitumumab with trifluridine-tipiracil in pretreated RAS wild-type metastatic colorectal cancer (VELO …
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: CAVE-2 GOIM Study: a Clinical Study of the Combination of Avelumab Plus Cetuximab as Rechallenge Strategy [Phase 2]
Phase 2 clinical trial investigating avelumab plus cetuximab as a rechallenge strategy for metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab [Phase 2]
Phase 2 trial investigating immunotherapy plus bevacizumab for colorectal liver metastases has completed.