Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: A Cross-sectional Study on the Association of Peptidoglycan Fragments Derived From Gut Microbiota With Colorectal Cancer
This clinical trial investigates whether peptidoglycan fragments derived from gut microbiota are associated with colorectal cancer and is cu…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC) [Phase 1]
A Phase 1 clinical trial investigating the combination of TACE, Axitinib, and Hydroxychloroquine for liver-dominant metastatic colorectal ca…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Phase 1/2 Study to Evaluate Safety, PK and Efficacy of the MYC-Inhibitor OMO-103 in Solid Tumours [Phase 1, Phase 2]
Phase 1/2 study evaluating the safety, pharmacokinetics, and efficacy of the MYC-inhibitor OMO-103 in solid tumors, including pancreatic and…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Text Message-Based Nudges Prior to Primary Care Visits to Increase Care Gap Closure [NA]
A completed trial evaluated text message nudges delivered before primary care visits to improve closing of care gaps. The study status is co…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: PRIORITY-CONNECT 2 Pilot Trial [NA]
The PRIORITY-CONNECT 2 Pilot Trial is currently recruiting. Sponsored by the Surgical Outcomes Research Centre, the study investigates liver…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Phase II Clinical Study of LTC004 in Patients With mCRC [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of LTC004 in patients with locally advanced or metastatic colorectal cancer, with the…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating toripalimab in combination with chemoradiotherapy for locally advanced colorectal cancer with dMMR/MSI-H s…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Anlotinib Plus Sintilimab as First-line Treatment for Patients With Advanced Colorectal Cancer (APICAL-CRC) [Phase 2]
Phase 2 trial update evaluating anlotinib plus sintilimab as first-line treatment for advanced colorectal cancer.
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Disitamab Vedotin Combined With Fruquintinib for mCRC With HER2 Expression [Phase 4]
Phase 4 trial investigating disitamab vedotin in combination with fruquintinib for metastatic colorectal cancer with HER2 expression.
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FDA approval · 2024-04-15FDA Approved: CAPECITABINE — Supplemental Application (Cipla USA Inc.)
The FDA approved Cipla USA Inc.'s supplemental application for Capecitabine, updating regulatory status for this cancer drug. The action lik…
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: Study of PF-07263689 in Participants With Selected Advanced Solid Tumors [Phase 1]
Phase 1 trial of PF-07263689 in selected advanced solid tumors was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017) [Phase 3]
Phase 3 LEAP-017 study evaluating lenvatinib plus pembrolizumab versus standard-of-care in metastatic colorectal cancer has completed enroll…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: Does IV Magnesium Improve Quality of Recovery With ERAS Protocols in Laparoscopic Colorectal Surgery? [Phase 3]
A Phase 3 trial investigating whether intravenous magnesium improves quality of recovery with ERAS protocols in laparoscopic colorectal surg…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: Clinical Study of Dexmedetomidine Administered Intranasally to Relieve Perioperative Anxiety and Depression in Patients With Colorectal Tumors [Phase 3]
Phase 3 clinical trial investigating intranasal dexmedetomidine to relieve perioperative anxiety and depression in patients with colorectal …
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps [NA]
Terminated clinical trial evaluating endoscopic optical coherence tomography for screening and diagnosing colorectal precancerous and malign…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Efficacy and Safety of Olaparib (MK-7339) With or Without Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Unresectable or Metastatic Colorectal Cancer (CRC) (MK-7339-003/LYNK-003) [Phase 3]
Phase 3 trial MK-7339-003/LYNK-003 evaluated olaparib with or without bevacizumab against bevacizumab with a fluoropyrimidine in unresectabl…
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Nimotuzumab Combined With Trifluridine/Tipiracil in the Treatment of Refractory Metastatic Colorectal Cancer [Phase 3]
A Phase 3 trial evaluating nimotuzumab in combination with trifluridine/tipiracil for refractory metastatic colorectal cancer is not yet rec…
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC [Phase 1]
Phase 1 dose-escalation study of MORAb-066 targeting tissue factor-expressing malignancies, including breast, pancreatic, colorectal, and no…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: Intrathecal Opioids for Colorectal Resection [Phase 4]
Phase 4 trial updating intrathecal opioid use for colorectal surgery; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: Combination of LTC004 and Regorafenib to Treat Patients With Advanced/Metastatic CRC [Phase 2]
Phase 2 trial investigating LTC004 in combination with regorafenib for advanced/metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors [Phase 3]
Phase 3 clinical trial evaluating predictors of sustaining physical activity in colorectal cancer survivors has completed.
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CLINICAL_TRIALS trial_result · 2024-03-18Clinical Trial Update: Fluid Challenge and Plasma Volume, During Surgery [Phase 4]
Phase 4 clinical trial update investigating fluid challenge and plasma volume during surgery.
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies [Phase 2]
Phase 2 trial of poziotinib in EGFR or HER2 activating mutations across advanced malignancies was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Multi-Line Therapy Trial in Unresectable Metastatic Colorectal Cancer [Phase 3]
Phase 3 clinical trial update for multi-line therapy in unresectable metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A safety and tolerability study of NC318 in advanced or metastatic solid tumors completed Phase 1/2 with results posted in 2024.