Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors
A real-world study evaluating nano-crystalline megestrol acetate for cachexia in patients with advanced digestive tumors is currently recrui…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors [EARLY_Phase 1]
An early-phase trial evaluating CDH17-targeted CAR-T cell therapy for advanced malignant solid tumors, including biliary tract cancer, color…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors [Phase 1]
This clinical trial update reports the completion of a Phase 1 study of CEA-targeted CAR-T therapy for CEA-positive advanced solid tumors, i…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy [NA]
Clinical trial evaluating colorectal anastomosis with preservation of the first sigmoid or left colonic artery during D3 lymphadenectomy for…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Deep Learning-Based Analysis of Colorectal Cancer Pathology Images: An Innovative Approach for Predicting Colorectal Cancer Subtypes
Completed clinical trial evaluating deep learning analysis of colorectal cancer pathology images, including Vision Transformer-based methods…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: A Prospective, Single Arm, Open Label, Phase II Clinical Study on the Efficacy and Safety of Ivonescimab (AK112) Combined With TAS-102 in the Treatment of Refractory MSS/pMMR Advanced Colorectal Cancer [NA]
This clinical trial update describes a prospective, single-arm, open-label Phase II study evaluating Ivonescimab (AK112) in combination with…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Robotic Colonoscopy Using the Triton 4.0 System in Adults for Screening, Surveillance, and Diagnosis of Lower Gastrointestinal Conditions [NA]
A clinical trial update for Neptune Medical's Triton 4.0 robotic colonoscopy system being evaluated in adults for screening, surveillance, a…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Tumor Immune Microenvironment Involvement in Colorectal Cancer Chemoresistance Mechanisms
This clinical trial investigates how the tumor immune microenvironment contributes to chemotherapy resistance in colorectal cancer. The stud…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers [Phase 1]
This Phase 1 trial update reports termination of the study evaluating BGB-3245 (brimarafenib) in combination with panitumumab for advanced o…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery [Phase 4]
Phase 4 clinical trial comparing intrathecal morphine to epidural analgesia for open colon surgery is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: EPA for Metastasis Trial 2 [Phase 3]
Phase 3 clinical trial update for EPA in metastatic colorectal cancer with liver metastases; the study is currently active but not recruitin…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: A Sociolinguistic-enabled Web Application to Develop Precision Health Intervention for African Americans [NA]
This completed clinical trial evaluated a sociolinguistic-enabled web application intended to develop precision health interventions for col…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Preserving Fertility After Colorectal Cancer Study
A clinical trial update indicates that the study 'Preserving Fertility After Colorectal Cancer' is currently recruiting to evaluate fertilit…
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FDA approval · 2025-04-17FDA Approved: AHZANTIVE — Supplemental Application (Valorum Biologics, LLC)
The FDA approved a supplemental application for AHZANTIVE (aflibercept-MRBB) from Valorum Biologics, LLC.
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma [Phase 2]
This Phase 2 trial of autologous tumor-infiltrating lymphocytes (MDA-TIL) in recurrent or refractory ovarian cancer, colorectal cancer, and …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: FOLFIRI + Cetuximab + Avelumab RAS Wild-type CRC [Phase 2]
Phase 2 trial assessing FOLFIRI plus cetuximab and avelumab in RAS wild-type colorectal cancer has completed, with results reported.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC) [Phase 2]
A Phase 2 trial by Redx Pharma evaluated RXC004 with or without nivolumab in metastatic, microsatellite-stable colorectal cancer with RNF43 …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Metastatic Colorectal Cancer (RAS-wildtype) After Response to First-line Treatment With FOLFIR Plus Cetuximab [Phase 3]
Phase 3 trial in metastatic colorectal cancer (RAS-wildtype) after response to first-line FOLFIR plus cetuximab has completed; the update no…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Detection of the Emergence of RAS (Rat Sarcoma Viral Oncogene Homolog) Mutations in Circulating DNA (Deoxyribonucleic Acid) in Patients With mCRC (Metastatic Colorectal Cancer) During Treatment With Anti-EGFR (Epidermal Growth Factor Receptor) Therapy [NA]
This clinical trial update investigates whether circulating tumor DNA shows emerging RAS mutations in patients with metastatic colorectal ca…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: The Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparomlimab and Tuvonralimab for the Treatment of Advanced Colorectal Cancer in Third-line Therapy and Subsequent Lines. [Phase 2]
Phase 2 trial in recruitment evaluating the combination of chidamide and regorafenib with iparomlimab and tuvonralimab for advanced colorect…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery [NA]
This clinical trial update notes a prospective evaluation of the Cornerstone Robotics Sentire Surgical System in major gastrointestinal and …
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Improving Muslim Women's Uptake of Cancer Screening (IMCAN) [NA]
Clinical trial update for IMCAN, a study to improve uptake of cancer screening among Muslim women; sponsored by the University of Sunderland…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer. [Phase 2]
A Phase 2 trial evaluating encorafenib with cetuximab versus irinotecan/cetuximab or FOLFIRI/cetuximab in Chinese patients with BRAF V600E-m…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: A Phase 1b Study of WU-NK-101 in Combination With Cetuximab [Phase 1]
A Phase 1b trial evaluates WU-NK-101 in combination with cetuximab for metastatic colorectal cancer and head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: A Clinical Study of Arfolitixorin in Patients With mCRC [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating arfolitixorin in patients with metastatic colorectal cancer is currently recruiting.