Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Function and Quality of Life After Emergency vs Planned Creation of a Stoma
A clinical trial evaluating function and quality of life after emergency versus planned creation of a stoma in colorectal cancer patients. T…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Comparison of the Diagnostic Performance of Different Artificial Intelligence Assisted Endocytoscopy for Colorectal Lesions
This clinical trial is currently recruiting to compare the diagnostic performance of AI-assisted endocytoscopy methods for colorectal lesion…
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FDA approval · 2025-05-23FDA Approved: IRINOTECAN HYDROCHLORIDE — Supplemental Application (Sagent Pharmaceuticals)
The FDA approved a supplemental application for irinotecan hydrochloride submitted by Sagent Pharmaceuticals, indicating an approval of chan…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer [Phase 3]
Phase 3 trial evaluating CMAB009 in combination with FOLFIRI as first-line treatment for RAS/BRAF wild-type metastatic colorectal cancer; th…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update reports termination of the NM21-1480 study in adults with advanced solid tumors, including non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC [Phase 1, Phase 2]
Status update on ONC-392 showing safety, pharmacokinetics, and preliminary efficacy in monotherapy and in combination with anti-PD-1 across …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors [Phase 1]
This ClinicalTrials.gov update describes a Phase 1 study evaluating MNPR-101-DFO*-89Zr as a diagnostic imaging agent for adults with various…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies [Phase 1]
Phase 1 study of COM902, a TIGIT inhibitor, in patients with advanced malignancies is ongoing and currently not recruiting.
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Adizutecan (ABBV-400) Moves Through the Body of Adult Participants With Unresectable Locally Advanced/Metastatic Colorectal Cancer [Phase 1, Phase 2]
This is an ongoing Phase 1/2 clinical trial evaluating adverse events and pharmacokinetics for intravenous Telisotuzumab Adizutecan (ABBV-40…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: An Exploratory Clinical Study Evaluating the Efficacy and Safety of Tunlametinib Combined With Fruquintinib in the Third-line Treatment of Advanced Colorectal Cancer Patients With RAS Mutations. [NA]
An exploratory clinical study to evaluate the efficacy and safety of tunlametinib plus fruquintinib as a third-line therapy for advanced col…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: [68Ga]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant Therapy [NA]
This ClinicalTrials.gov update reports the completion of a trial evaluating the Ga-68 labeled GZP PET imaging tracer for early prediction of…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal Cancer [Phase 1]
A first-in-human Phase 1 trial of CC-3, a CD276xCD3 bispecific antibody, is recruiting for colorectal cancer with listed indications includi…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors [Phase 1]
Phase 1 dose-escalation study of MNPR-101-PCTA-177Lu in solid tumors is currently recruiting across multiple cancer indications.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black Adults [NA]
A feasibility trial called EQUITA evaluating a faith-placed intervention to increase screening uptake for breast cancer, colorectal cancer, …
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China [Phase 1]
The Phase 1 study of JAB-3312 in adults with advanced solid tumors in China has completed.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: A Clinical Study on the Efficacy and Safety of Fruquintinib in Combination With PD-1 Monoclonal Antibody and Chidamide in Refractory MSS Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating Fruquintinib in combination with a PD-1 monoclonal antibody and chidamide for refractory MSS metastatic co…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Autologous CAR-T Cells (WD-01) for Metastatic Colorectal Cancer [EARLY_Phase 1]
An early-phase trial of WD-01 autologous CAR-T cells for metastatic colorectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Sarcopenia in Colorectal Cancer Patients, Intervention Study [NA]
A recruiting clinical trial evaluating an intervention for sarcopenia in colorectal cancer patients, focusing on postoperative outcomes.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Use of Alternative and Complementary Medicine by Colorectal Cancer Patients [NA]
A clinical trial update studying the use of alternative and complementary medicine among colorectal cancer patients; the trial is currently …
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Acupuncture Pilot Study for Cancer-related Cognitive Function [Phase 2]
This update covers a Phase 2 acupuncture pilot study investigating cancer-related cognitive function across breast, colorectal, gynecologic,…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: Glumetinib Combined With Fruquintinib in the Treatment of MET Amplification or Protein Overexpression in Third-Line Unresectable Metastatic Colorectal Cancer [Phase 1, Phase 2]
This clinical trial update describes Glumetinib combined with Fruquintinib being studied for MET amplification or overexpression in third-li…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer [Phase 2]
Daiichi Sankyo's U3-1402 in advanced or metastatic colorectal cancer has been terminated in a Phase 2 study, with results posted in May 2025…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Genotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer [Phase 2]
This Phase 2 trial investigates genotype-directed dosing of irinotecan within a FOLFIRI plus bevacizumab regimen for metastatic colorectal c…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Primary Colorectal Signet Ring Cell Carcinoma and the Risk of Multiple Primary Gastrointestinal Malignancies
Completed clinical trial examining primary colorectal signet ring cell carcinoma and the risk of multiple primary gastrointestinal malignanc…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Study of Dabrafenib Plus Cetuximab/Panitumumab With FOLFOX in the First Line of Therapy in People With Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating dabrafenib in combination with cetuximab or panitumumab plus FOLFOX as first-line therapy for metastatic colorectal…