Colorectal Cancer

CLINICAL_TRIALS research · 2025-05-30

Clinical Trial Update: Localized Treatment Versus Palliative Chemotherapy in CRC Patients With 10 or More CRLM [Phase 3]

A Phase 3 trial comparing localized treatment versus palliative chemotherapy in colorectal cancer patients with 10 or more colorectal liver …

CLINICAL_TRIALS research · 2025-05-30

Clinical Trial Update: Liquid BiOpsy, Lung and Colon Cancer in AndaluciA

A clinical trial update about a liquid biopsy program in Andalusia for non-small cell lung cancer and colorectal cancer, currently enrolling…

CLINICAL_TRIALS research · 2025-05-30

Clinical Trial Update: Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine [Phase 1, Phase 2]

An ongoing Phase 1/2 trial evaluates adding an anti-IL-1α monoclonal antibody to trifluridine/tipiracil vs placebo in metastatic colorectal …

CLINICAL_TRIALS trial_result · 2025-05-30

Clinical Trial Update: Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System

Completed clinical trial evaluating strategies to improve colonoscopy quality for colorectal cancer screening in the National VA Healthcare …

CLINICAL_TRIALS research · 2025-05-30

Clinical Trial Update: Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer [Phase 1]

Phase 1 study evaluating an immune response activation approach for unresectable metastatic colorectal cancer or CEA-positive metastatic bre…

CLINICAL_TRIALS trial_result · 2025-05-29

Clinical Trial Update: Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy [Phase 1, Phase 2]

This update reports results from a Phase 1/2 study of NGM120 in combination therapy for patients with advanced solid tumors, including pancr…

CLINICAL_TRIALS research · 2025-05-29

Clinical Trial Update: Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors [Phase 1]

Phase 1 trial evaluating safety and biomarker signals for DK210, an EGFR-targeting therapy, across multiple EGFR-positive solid tumors; curr…

CLINICAL_TRIALS trial_result · 2025-05-29

Clinical Trial Update: SafeHeal Anastomosis Feasibility Evaluation (SAFE)-2023 Study [NA]

This clinical trial update describes the SAFE-2023 study evaluating SafeHeal's anastomosis feasibility in colorectal cancer; the trial is cu…

CLINICAL_TRIALS research · 2025-05-29

Clinical Trial Update: CRC Detection Reliable Assessment With Blood

A New Day Diagnostics trial is evaluating a blood-based method for detecting colorectal cancer and colorectal adenomas; the study is current…

CLINICAL_TRIALS trial_result · 2025-05-29

Clinical Trial Update: Comparing the Effectiveness of Written Vs Verbal Advice for First Degree Relatives of Colorectal Cancer Patients [NA]

A completed clinical trial from Ramathibodi Hospital compared written versus verbal advice for first-degree relatives of colorectal cancer p…

CLINICAL_TRIALS research · 2025-05-29

Clinical Trial Update: A First-In-Human Trial of pTTL in Advanced Colorectal Cancer [Phase 1, Phase 2]

Neogap Therapeutics AB reports a first-in-human Phase 1/Phase 2 trial of pTTL for advanced colorectal cancer, currently recruiting.

CLINICAL_TRIALS research · 2025-05-29

Clinical Trial Update: Microbiome-based Diagnostic Tool for the Screening of Colorectal Cancer (GUILTI)

A clinical trial is evaluating a microbiome-based diagnostic tool for colorectal cancer screening, sponsored by the Catholic University of t…

CLINICAL_TRIALS research · 2025-05-29

Clinical Trial Update: Epidemiological Study to Monitor Study Participants With Resected Stage II (High Risk) or Stage III Colorectal Cancer for Circulating Tumor DNA Before, During and After Their Treatment With Adjuvant Chemotherapy

A BioNTech-sponsored epidemiological study monitoring circulating tumor DNA in participants with resected stage II (high risk) or stage III …

CLINICAL_TRIALS research · 2025-05-28

Clinical Trial Update: Organ Preservation in Rectal AdenoCa Using Hypofractionated Pelvic RT(Hypo-OPRA) [Phase 2]

A Phase 2 study evaluating organ preservation in rectal cancer using hypofractionated pelvic radiotherapy; recruitment is ongoing.

CLINICAL_TRIALS research · 2025-05-28

Clinical Trial Update: Trifluridine/Tipiracil Plus Regorafenib vs Trifluridine/Tipiracil Plus Bevacizumab for Refractory Metastatic Colorectal Cancer [Phase 3]

Phase 3 clinical trial update comparing Trifluridine/Tipiracil plus Regorafenib versus Trifluridine/Tipiracil plus Bevacizumab for refractor…

CLINICAL_TRIALS research · 2025-05-28

Clinical Trial Update: Exploratory Study of Intermittent Hypoxia Intervention on Colorectal Cancer [NA]

An exploratory study at Capital Medical University is evaluating intermittent hypoxia intervention for colorectal cancer; the trial is curre…

CLINICAL_TRIALS research · 2025-05-28

Clinical Trial Update: Early Diagnosis and Recurrence Monitoring of Colorectal Cancer

A clinical trial sponsored by Huashan Hospital focuses on early diagnosis and recurrence monitoring of colorectal cancer. The study status i…

CLINICAL_TRIALS trial_result · 2025-05-25

Clinical Trial Update: Impact of Perioperative Hyperoxia on Cancer Recurrence and Mortality After Elective Colorectal Cancer Surgery

This completed clinical trial investigates whether perioperative hyperoxia influences colorectal cancer recurrence and mortality after elect…

CLINICAL_TRIALS trial_result · 2025-05-25

Clinical Trial Update: A Digital Therapeutic Solution for Cancer Patients [NA]

A completed clinical trial update for a digital therapeutic targeting cancer patients. The study covers prostate cancer, colorectal cancer, …