Colorectal Cancer
📧 Sign up to get email alerts when something new happens for Colorectal Cancer.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Predicting Local and Distant Recurrence in T1 Colorectal Cancer
This clinical trial update reports the completed status of a study evaluating predictors of local and distant recurrence in T1 colorectal ca…
-
CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM [Phase 1, Phase 2]
An early-phase trial evaluating IP-001 following microwave ablation or irreversible electroporation for colorectal cancer with liver metasta…
-
CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study [NA]
A pivotal colorectal cancer device trial (SAFE-2) evaluating the SafeHeal Colovac Colorectal Anastomosis Protection Device was terminated; r…
-
CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer [EARLY_Phase 1]
Dose-expansion early-phase trial evaluating intravenous HNF4α srRNA for unresectable or metastatic colorectal cancer. The study is currently…
-
CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer [NA]
A clinical trial update indicating recruitment is ongoing to evaluate the effects of aerobic exercise on skeletal muscle remodeling in color…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy
The document describes a clinical trial that uses comprehensive genomic profiling in colorectal cancer patients with isolated liver metastas…
-
CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Single-arm, Phase II Clinical Study [Phase 2]
A Phase II single-arm trial is evaluating liposomal irinotecan with 5-FU/leucovorin and bevacizumab as second-line therapy for advanced colo…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203) [Phase 2]
This is a Phase 2 master protocol evaluating SAR444245 in combination with other anticancer therapies for several gastrointestinal cancers; …
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy
This clinical trial seeks to develop and validate a microbiota- and metabolite-based model to predict recurrence of high-risk colorectal pol…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: EXERCISING TOGETHER for Couples Coping With Cancer [NA]
This clinical trial update reports the completion and posted results of a study evaluating an exercise program for couples coping with cance…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Expectations and Priorities of Elderly Patients for a First Medical Treatment for Cancer
Completed clinical trial from Institut Bergonié evaluating elderly patients' expectations and priorities for a first-line cancer treatment a…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Nivolumab and Ipilimumab in Anti-PD1-Resistant dMMR/MSI mCRC [Phase 2]
A Phase 2 clinical trial evaluates nivolumab plus ipilimumab for anti-PD1-resistant dMMR/MSI metastatic colorectal cancer. The study is curr…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Study of Magrolimab Given Together With FOLFIRI/Bevacizumab (BEV) in Participants With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC) [Phase 2]
Phase 2 study of magrolimab with FOLFIRI and bevacizumab in previously treated advanced, inoperable metastatic colorectal cancer was termina…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Phase II Randomized Therapeutic Optimization Trial for Subjects With Refractory Metastatic Colorectal Cancer Using ctDNA: Rapid 1 Trial [Phase 2]
A Phase II randomized trial evaluating ctDNA-guided therapeutic optimization in patients with refractory metastatic colorectal cancer has be…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Evaluating AI and Human Expert Decisions in Colorectal Cancer
A clinical trial from Peking University Cancer Hospital & Institute is evaluating AI-assisted decision-making alongside human expert input i…
-
CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Study to Investigate LYL845 in Adults With Solid Tumors [Phase 1]
Lyell Immunopharma reports termination of the Phase 1 trial evaluating LYL845 in adults with solid tumors, including melanoma, non-small cel…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Clinical Study of Irinotecan Liposome (II)-Based Combination Treatment for Irinotecan-resistant Colorectal Cancer. [Phase 2]
A Phase 2 clinical trial is testing a liposomal irinotecan-based combination therapy for metastatic colorectal cancer, currently recruiting …
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer [Phase 1]
Phase 1 trial evaluating intraperitoneal aerosolized nanoliposomal irinotecan (Nal-IRI) for peritoneal carcinomatosis from gastrointestinal …
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH) [NA]
This clinical trial update describes the REACH study, a randomized trial evaluating whether combining resistance and aerobic exercise improv…
-
CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation [Phase 2]
Phase 2 trial evaluating a stop-and-go strategy with FOLFOX plus panitumumab as first-line treatment for metastatic colorectal cancer withou…
-
CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Standard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer [Phase 2]
A Phase 2 trial comparing standard chemotherapy vs immunotherapy as second-line treatment for MSI-high metastatic colorectal cancer has comp…
-
CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: An Exploratory Study on Gene Methylation Detection of Colorectal Cancer
This exploratory clinical trial investigates gene methylation detection for colorectal cancer (and related colorectal adenomas) and is curre…
-
CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast
This clinical trial update indicates the study, which collected blood and stool samples from subjects diagnosed with colorectal cancer or co…
-
CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor [Phase 1]
Phase 1 trial evaluating carbon nanoparticle-loaded iron (CNSI-Fe(II)) in patients with advanced solid tumors has completed, with results po…
-
CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy
This clinical trial update summarizes how microsatellite instability and the genomic profile of colorectal cancer evolve during immune check…