Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival [NA]
Clinical trial PROGRESS is evaluating a precision oncology approach using genomic reflexive evaluations to guide study selection and surviva…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors [Phase 2]
Telix's phase 2 trial of the CAIX-targeting PET tracer 89Zr-girentuximab in CAIX-positive solid tumors was terminated.
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: A Study of Mental Health Care in People With Cancer [NA]
Memorial Sloan Kettering Cancer Center is recruiting for a study to evaluate mental health care in people with cancer, including breast, col…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Role of Cross Sectional Imaging Modalities in the Diagnosis and Characterization of Colonic Masses
This document is a clinical trial update about evaluating cross-sectional imaging techniques for diagnosing and characterizing colonic masse…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Dual EGFR/HER2 Blockade Combined With Irinotecan for the Treatment of HER2-Positive Metastatic Colorectal Cancer [Phase 2]
This Phase 2 trial evaluates combining irinotecan with dual EGFR/HER2 blockade for HER2-positive metastatic colorectal cancer; the study sta…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: French Assessment of MRD by Liquid Biopsies in Stage III CRC Patients (FRENCH.MRD.CRC)
This clinical trial update describes a French assessment of minimal residual disease in stage III colorectal cancer using liquid biopsies (F…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers [Phase 2]
Phase 2 study evaluating adoptive transfer of tumor-infiltrating lymphocytes (TIL) for advanced solid cancers, with multiple site-specific i…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE) [Phase 2]
A Phase II platform trial evaluating cemiplimab alone or with fianlimab, or other novel combinations, for colorectal cancer with minimal res…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Illness Perception and Quality of Life in Colorectal Cancer With Ascites
A completed clinical trial evaluating illness perception and quality of life in patients with colorectal cancer with ascites (MSI-H).
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver [Phase 3]
A Phase 3 trial is evaluating systemic oxaliplatin or intra-arterial chemotherapy with leucovorin-5-fluorouracil, with or without irinotecan…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: A Beta-only IL-2 ImmunoTherapY Study [Phase 1, Phase 2]
Medicennа Therapeutics is evaluating a beta-only IL-2 immunotherapy (MDNA11) in Phase 1/2 across multiple advanced solid tumors; recruitment…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
The trial sponsored by Amsterdam UMC (VUmc site) is currently recruiting to evaluate adaptive anastomosis techniques for anterior resection …
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers [NA]
A clinical trial comparing time-restricted eating to daily calorie restriction in adults, assessing body weight changes and colorectal cance…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Microbiome and Colorectal Cancer Recurrence
A completed clinical trial update examining the relationship between the gut microbiome and recurrence of colorectal cancer.
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Lapatinib Plus Trametinib in KRAS Mutant NSCLC [Phase 1, Phase 2]
Phase 1/2 trial results assess the combination of lapatinib and trametinib in KRAS-mutant cancers, including colorectal cancer and non-small…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Phase I PK Comparison of HLX05 vs. Erbitux® in Healthy Chinese Males: Safety, Immunogenicity, and Pharmacokinetics [Phase 1]
This ClinicalTrials.gov update outlines a Phase 1 pharmacokinetic comparison between HLX05 and Erbitux (cetuximab) in healthy Chinese male v…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Single Nucleotide Polymorphism(SNP)Study. ICORG 08-40, V4
A clinical trial update indicates the SNP study ICORG 08-40, Version 4, sponsored by Cancer Trials Ireland, for colorectal cancer and non-sm…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Plasma Biomarkers C-RAC, ICORG 12-27, V1
This document reports the termination of the ICORG 12-27 trial evaluating the plasma biomarker C-RAC in colorectal cancer.
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal Cancer [Phase 1]
Phase 1 dose-escalation study of lithium in combination with oxaliplatin and capecitabine for advanced esophago-gastric or colorectal cancer…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors [Phase 1]
This Phase 1 trial assesses Autogene Cevumeran (RO7198457) as a single agent and in combination with atezolizumab across multiple locally ad…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of regorafenib and pembrolizumab in adults with advanced or metastatic colorectal c…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: Safety Study of Radio-labeled huA33 Antibody in Colorectal Cancer [NA]
This document reports the completion of a safety study evaluating radio-labeled huA33 antibody for colorectal cancer.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Stage II/III Colorectal Cancer Recurrence
A clinical trial update notes that a Stage II/III colorectal cancer recurrence study is currently recruiting at City of Hope Medical Center.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Fruquintinib vs Bevacizumab Combined With Irinotecan Liposome and Capecitabine as Second-Line Therapy for Advanced Metastatic Colorectal Cancer [Phase 2]
This entry describes a Phase 2 trial comparing Fruquintinib to Bevacizumab in combination with Irinotecan liposome and Capecitabine as secon…