Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating BOLD-100 in combination with FOLFOX for advanced solid tumors, including colorectal cancer, pancreatic…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions [Phase 1, Phase 2]
A Phase 1/2 study evaluating darovasertib (IDE196), a PKC inhibitor, in patients with solid tumors harboring GNAQ/GNA11 mutations or PRKC fu…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Comparative Study on the Short- and Long-term Efficacy of Q-ISR, Traditional Sub-ISR, and t-ISR [Phase 2]
Phase 2 clinical trial comparing Q-ISR, Traditional Sub-ISR, and t-ISR for colorectal cancer is currently recruiting.
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EMA approval · 2026-01-27EMA Authorised: Avastin (bevacizumab) — Roche Registration GmbH
The EMA authorised Avastin (bevacizumab) under Roche Registration GmbH for multiple cancer indications. The listed diseases include non-smal…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Epigenetic Factors of Colorectal Adenoma in Korean
A clinical trial investigating epigenetic factors in colorectal adenoma and precancerous colorectal cancer in a Korean population; currently…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD) [Phase 1]
Phase 1 trial evaluating immunotherapy using ex vivo pre-activated and expanded CB-NK cells in combination with cetuximab for colorectal can…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Neoadjuvant Chemotherapy, Anti-PD-1 Antibody and Sitagliptin for Locally Advanced pMMR CRC [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating neoadjuvant chemotherapy combined with an anti-PD-1 antibody and sitagliptin for locally adva…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal Cancer [Phase 2, Phase 3]
Duloxetine is being studied in Phase 2/Phase 3 trials to prevent oxaliplatin-induced peripheral neuropathy in patients with stage II-III col…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer [Phase 1]
A Phase 1 clinical trial evaluating Ivonescimab and ADG126, alone and in combination with leucovorin plus fluorouracil or FOLFIRI, for advan…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: First in Human Study of SIM0610 in Solid Tumors [Phase 1]
A first-in-human Phase 1 study of SIM0610 in solid tumors is underway, evaluating safety and dosing across multiple indications including No…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study [NA]
This update reports completion of the INSPIRE-AYA clinical trial, an interactive survivorship program aimed at improving healthcare resource…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) [NA]
Clinical trial update for Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) assessing a text-based mindfulness …
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors [Phase 1]
Phase 1 clinical trial update for a CEA-targeting CAR-T therapy (PTC13) in CEA-positive advanced malignant solid tumors, currently recruitin…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Pilot Testing of a Colorectal Cancer Education Program [NA]
A pilot test of a colorectal cancer education program is planned, and the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders
Memorial Sloan Kettering Cancer Center is recruiting families for genetic studies of familial lymphoproliferative disorders, including lymph…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Fruquintinib Versus Bevacizumab Plus Chemotherapy in Second-Line RAS-Mutant Metastatic Colorectal Cancer (FRU-RAS) [Phase 3]
A Phase 3 trial comparing Fruquintinib to Bevacizumab plus chemotherapy as second-line therapy for RAS-mutant metastatic colorectal cancer i…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers [Phase 2]
Phase 2 study evaluating the PET imaging agent [18F]FAPI-74 in gastrointestinal cancers has completed.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: First in Human Study of QLS5316 in Solid Tumors [Phase 1]
This is a first-in-human Phase 1 trial of QLS5316 in various solid tumors; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Phase Ib/II Study to Evaluate HLX43 Combined With HLX07 or Serplulimab in Patients With Advanced or Metastatic Colorectal Cancer [Phase 1, Phase 2]
Phase Ib/II trial evaluating HLX43 in combination with HLX07 or Serplulimab for advanced or metastatic colorectal cancer (colon cancer adeno…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Clinical Characteristics and Prognosis of Simultaneous Versus Delayed Resection for Synchronous Colorectal Liver Metastasis: A Nationwide Multicenter Study Utilizing Propensity Score Matching Analysis
A nationwide multicenter study using propensity score matching compares simultaneous versus delayed resection for synchronous colorectal liv…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Study to Explore the Third-line Treatment of Fruquintinib Combined With Serplulimab in Advanced Non-liver-limited Metastatic Colorectal Cancer: a Single-center, Phase 2 Study [Phase 2]
Phase 2, single-center trial evaluating third-line treatment with Fruquintinib plus Serplulimab in advanced non-liver-limited metastatic col…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Optimization of Adaptive Text Messages for Cancer Survivors (OATS II) [NA]
This update notes the completion of the OATS II trial evaluating adaptive text messaging for cancer survivors, with results posted on 2026-0…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: PRIORITY-CONNECT 2 Trial [NA]
The PRIORITY-CONNECT 2 trial (NCT06976710), sponsored by Surgical Outcomes Research Centre (SOuRCe), is currently recruiting for colorectal …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Strategies for Optimizing a Mailed FIT Program in Appalachia [NA]
A clinical trial update outlines strategies to optimize a mailed fecal immunochemical test (FIT) program for colorectal cancer screening in …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Evaluation of Circulating Immune Response After Histosonics in Colorectal Cancer (ECHO-CRC) [Phase 1]
A Phase 1 clinical trial (ECHO-CRC) is evaluating the circulating immune response after Histosonics in colorectal cancer and is currently in…