Colorectal Cancer

• CLINICAL_TRIALS trial_result · 2016-11-28
  Clinical Trial Update: Pharmacogenomic Study in Patients of Lung, Colorectal and Head/Neck Cancers Receiving Chemotherapy

  A completed pharmacogenomic study evaluating chemotherapy response in patients with lung cancer, colorectal cancer, and head and neck cancer…

• CLINICAL_TRIALS trial_result · 2016-11-25
  Clinical Trial Update: Polyp Detection With The Peerscope System™ [Phase 2]

  Phase 2 trial update for the Peerscope System, evaluating detection of colorectal polyps and adenomas and potential colorectal cancer. The t…

• CLINICAL_TRIALS research · 2016-11-25
  Clinical Trial Update: Transanal Tube Drainage in Endoscopic Submucosal Dissection of the Colorectal Tumor [NA]

  The document describes a clinical trial sponsored by Fudan University evaluating transanal tube drainage during endoscopic submucosal dissec…

• CLINICAL_TRIALS research · 2016-11-23
  Clinical Trial Update: Prehabilitation in Elective Colorectal Resection: A Pilot Study (Prehab) [NA]

  A pilot clinical trial update on prehabilitation before elective colorectal resection for colorectal cancer; current trial status is unknown…

• CLINICAL_TRIALS trial_result · 2016-11-22
  Clinical Trial Update: A Phase II Study of Cetuximab Plus Irinotecan in Patients With EGFR-detectable Metastatic Colorectal Carcinoma [Phase 2]

  A Phase II trial evaluating cetuximab in combination with irinotecan in EGFR-detectable metastatic colorectal cancer has completed.

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• CLINICAL_TRIALS research · 2016-11-17
  Clinical Trial Update: RAS Mutation Testing in the Circulating Blood of Patients With Metastatic Colorectal Cancer

  This document provides a clinical trial update on circulating tumor DNA RAS mutation testing in patients with metastatic colorectal cancer. …

• CLINICAL_TRIALS research · 2016-11-16
  Clinical Trial Update: Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer [Phase 2]

  A Phase 2 clinical trial update for identifying biomarkers of response to aflibercept (Zaltrap) in metastatic colorectal cancer has been ter…

• CLINICAL_TRIALS trial_result · 2016-11-11
  Clinical Trial Update: Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer [Phase 3]

  Phase 3 trial comparing laparoscopic-assisted resection versus open resection for rectal cancer has completed; results posted in 2016.

• CLINICAL_TRIALS trial_result · 2016-11-09
  Clinical Trial Update: Efficacy and Safety of Olaparib in Pretreated Patients With Measurable Colorectal Cancer, Stratified by Microsatellite Instability (MSI) Status [Phase 2]

  Phase 2 trial assessing the efficacy and safety of olaparib in pretreated colorectal cancer patients, analyzed by MSI status; results posted…

• CLINICAL_TRIALS trial_result · 2016-11-09
  Clinical Trial Update: An Observational Study of First-Line Capecitabine Based Chemotherapy in Participants With Metastatic Colorectal Cancer

  This clinical trial update reports results from an observational study of first-line capecitabine-based chemotherapy in patients with metast…

• CLINICAL_TRIALS research · 2016-11-08
  Clinical Trial Update: A Study of Chimeric Antigen Receptor T Cells Combined With Interventional Therapy in Advanced Liver Malignancy [Phase 1, Phase 2]

  This document updates a Phase 1/Phase 2 clinical trial evaluating CAR-T cell therapy combined with interventional therapy for advanced liver…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Safety and Efficacy Study of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI as Second Line Therapy in Participants With KRAS Wild-Type Metastatic Colorectal Cancer (mCRC) [Phase 2]

  Phase 2 trial comparing MEHD7945A plus FOLFIRI versus cetuximab plus FOLFIRI as second-line therapy for KRAS wild-type metastatic colorectal…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: OPAL Study: A Study of Avastin (Bevacizumab) in Combination With FOLFOXIRI in Patients With Previously Untreated Metastatic Colorectal Cancer [Phase 2]

  A Phase 2 trial evaluating Avastin (bevacizumab) in combination with FOLFOXIRI as first-line therapy for patients with untreated metastatic …

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer [Phase 2]

  Phase 2 study of capecitabine (Xeloda) in patients with advanced or metastatic colorectal cancer has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer [Phase 2]

  Phase 2 trial update of capecitabine (Xeloda) in advanced or metastatic colorectal cancer, sponsored by Hoffmann-La Roche.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Dose-finding Study of RO5323441 in Patients With Metastatic Treatment-Refractory Colorectal or Ovarian Cancer [Phase 1]

  This clinical trial update reports a Phase 1 dose-finding study of RO5323441 in patients with metastatic, treatment-refractory colorectal or…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Capecitabine Rapid Disintegrating Tablets (RDT) Versus Commercial Xeloda in Patients With Solid Tumours [Phase 1]

  A Phase 1 trial comparing Capecitabine Rapid Disintegrating Tablets (RDT) to the commercial Xeloda formulation in patients with solid tumors…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Dulanermin Administered in Combination With Camptosar®/Erbitux® Chemotherapy or FOLFIRI (With or Without Bevacizumab) in Subjects With Previously Treated Metastatic Colorectal Cancer [Phase 1]

  Phase 1 trial evaluating dulanermin in combination with irinotecan-based chemotherapy (Camptosar/Erbitux) or FOLFIRI (with or without bevaci…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Dulanermin Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced, Recurrent, or Metastatic Colorectal Cancer [Phase 1]

  Phase 1 study evaluating dulanermin with the FOLFOX regimen and bevacizumab for previously untreated locally advanced, recurrent, or metasta…

• CLINICAL_TRIALS research · 2016-11-02
  Clinical Trial Update: An Observational Study of Avastin and Conventional Chemotherapy in Patients >/= 70 Years of Age With Previously Untreated Metastatic Colorectal Cancer (AVAPLUS)

  An observational study evaluating Avastin in combination with conventional chemotherapy in patients aged 70 and older with untreated metasta…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: An Observational Study of Xeloda (Capecitabine) Monotherapy in Patients With Colorectal Cancer (AXEL)

  This update reports a terminated observational study of capecitabine (Xeloda) as monotherapy for colorectal cancer.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: BEVERLY-C: An Observational Study of Avastin (Bevacizumab) in First-Line Treatment in Elderly Patients With Metastatic Colorectal Cancer

  An observational study assessing first-line use of bevacizumab (Avastin) in elderly patients with metastatic colorectal cancer; the trial st…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer in Italy (BEWARE)

  This is an observational study update evaluating Avastin (bevacizumab) in patients with metastatic colorectal cancer in Italy. The BEWARE st…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: An Observational Study of Avastin (Bevacizumab) in First Line in Patients With Metastatic Colorectal Cancer (AVANiS)

  This clinical trial update reports the completion of an observational study evaluating Avastin (bevacizumab) as first-line therapy for metas…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Cancer of the Colon or Rectum

  This document provides an observational study update on Avastin (bevacizumab) used in patients with metastatic colorectal cancer (cancer of …