Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-12-27FDA Approved: FLUOROURACIL — Supplemental Application (Eugia US LLC)
FDA approved a supplemental application for Fluorouracil (5-fluorouracil) from Eugia US LLC.
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CLINICAL_TRIALS trial_result · 2016-12-21Clinical Trial Update: Intravenous Iron for Correction of Anaemia After Colorectal Surgery [Phase 4]
Phase 4 clinical trial evaluating intravenous iron to correct iron-deficiency anemia after colorectal surgery.
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CLINICAL_TRIALS trial_result · 2016-12-19Clinical Trial Update: PROSPECT-C: A Study of Biomarkers of Response or Resistance to Anti-EGFR Therapies in Metastatic Colorectal Cancer
A completed clinical trial investigating biomarkers that predict response or resistance to anti-EGFR therapies in metastatic colorectal canc…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Visualization of Anti-angiogenic Effects With Perfusion Computed Tomography (CTP) [NA]
This entry notes the termination of a clinical trial evaluating the use of perfusion computed tomography to visualize anti-angiogenic effect…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Preventive Health Behavior in Women
This entry reports a completed University of Michigan clinical trial evaluating preventive health behaviors related to colorectal cancer ris…
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: Neoadjuvant Celecoxib and Capecitabine Combined With Pelvic Irradiation in Treating Patients With Stage II or Stage III Adenocarcinoma (Cancer) of the Rectum [Phase 2]
A Phase 2 trial evaluating neoadjuvant celecoxib and capecitabine with pelvic irradiation in stage II/III rectal adenocarcinoma was terminat…
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: Arsenic Trioxide, Fluorouracil, and Leucovorin in Treating Patients With Stage IV Colorectal Cancer That Has Relapsed or Not Responded to Treatment [Phase 1]
Phase 1 clinical trial evaluating arsenic trioxide in combination with fluorouracil and leucovorin for patients with stage IV colorectal can…
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FDA approval · 2016-12-14FDA Approved: FLUOROURACIL — Supplemental Application (Eugia US LLC)
The FDA has approved a supplemental application for Fluorouracil from Eugia US LLC, formalizing an update to the product under the ANDA path…
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: Study of Lurbinectedin (PM01183) in Combination With Capecitabine in Patients With Metastatic Breast Cancer (MBC), Pancreatic Cancer (PC) or Metastatic Colorectal Cancer (CRC). [Phase 1]
This Phase 1 study evaluated the combination of lurbinectedin with capecitabine in patients with metastatic breast cancer, pancreatic cancer…
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: A Study of the Efficacy and Safety of PerOx Quench on the Prevention of Oxaliplatin Treatment Induced Neuropathy [NA]
Clinical trial evaluating PerOx Quench to prevent oxaliplatin-induced neuropathy in colorectal and gastric cancer. The study has been termin…
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FDA approval · 2016-12-12FDA Approved: CAPECITABINE 150MG — Original Application (Armas Pharmaceuticals Inc.)
FDA approves Armas Pharmaceuticals Inc.'s Capecitabine 150 mg as an Original Application generic drug (ANDA 207456).
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FDA approval · 2016-12-09FDA Approved: OXALIPLATIN — Supplemental Application (Winthrop U.S, a business of sanofi-aventis U.S. LLC)
FDA approved a supplemental application for oxaliplatin (brand Eloxatin). The supplemental submission was filed by Winthrop U.S., a business…
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CLINICAL_TRIALS withdrawal · 2016-12-09Clinical Trial Update: Irinotecan Hydrochloride With FOLFIRI and Cetuximab as First-Line Therapy in Treating Patients With RAS Wild-Type Colorectal Cancer [Phase 1]
The Phase 1 trial evaluating irinotecan hydrochloride with FOLFIRI and cetuximab for first-line treatment of RAS wild-type colorectal cancer…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Effect of Celecoxib on Perioperative Inflammatory Response in Colon Cancer [NA]
The document reports on a terminated clinical trial evaluating whether celecoxib affects the perioperative inflammatory response in colorect…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Irinotecan or Fluorouracil Plus Leucovorin in Treating Patients With Previously Treated Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating irinotecan or fluorouracil with leucovorin in patients with previously treated metastatic colorectal cancer has c…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluated a first-line combination of irinotecan, fluorouracil, leucovorin, and oxaliplatin for metastatic colorectal cancer…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: "Cancersensor" Metastasis Resection
A completed clinical trial evaluating the Cancersensor device for metastasis resection in metastatic colorectal cancer.
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CLINICAL_TRIALS research · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 trial evaluating CAR-pNK cell immunotherapy for MUC1-positive relapsed or refractory solid tumors; current status is not provide…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: CAR-T Cell Immunotherapy in MUC1 Positive Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 CAR-T cell therapy targeting MUC1 is being investigated for glioblastoma, colorectal cancer, and gastric cancer.
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: Chemopreventive Action of Mesalazine on Colorectal Cancer: a Pilot Study for an "in Vivo" Evaluation of the Molecular Effects on β-catenin Signaling Pathway. [Phase 2]
Phase 2 pilot trial assessing mesalazine for chemoprevention in colorectal cancer by evaluating its effect on beta-catenin signaling; the st…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating an investigational drug to prevent chemotherapy-induced diarrhea in previously untreated metastatic colorectal ca…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Comparative Effectiveness of CTC & OC
A completed comparative-effectiveness clinical trial in colorectal cancer evaluating CTC versus OC, sponsored by Fox Chase Cancer Center.
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CLINICAL_TRIALS research · 2016-11-30Clinical Trial Update: Cetuximab Monotherapy Maintenance Treatment in mCRC [Phase 2, Phase 3]
This document provides an update on a Phase 2/Phase 3 trial evaluating cetuximab as monotherapy maintenance treatment for metastatic colorec…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Endoscopic Ultrasound and Contrast Enhancement for Staging and Evaluation of Angiogenesis of Left Sided Colon Cancers [NA]
The trial evaluated endoscopic ultrasound with contrast enhancement for staging and assessing angiogenesis in left-sided colon cancers and h…
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CLINICAL_TRIALS trial_result · 2016-11-28Clinical Trial Update: Colorectal Cancer Metastatic [Phase 3]
A Phase 3 trial in metastatic colorectal cancer sponsored by Sanofi has completed and posted results.