Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Socioeconomic Position in Acute Colorectal Cancer Surgery
A clinical trial update from Zealand University Hospital evaluating how socioeconomic position influences outcomes in acute colorectal cance…
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: To Investigate Risk of Colorectal Neoplasms in First-degree Relatives of Patients With Non-advanced Adenomas
A completed clinical trial from the Chinese University of Hong Kong evaluated whether first-degree relatives of patients with non-advanced c…
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: A Trial of PledOx + FOLFOX6 Compared to Placebo + FOLFOX6 in Patients With Metastatic Colorectal Cancer [Phase 1, Phase 2]
A Phase 1/2 trial evaluating PledOx in combination with FOLFOX6 versus placebo with FOLFOX6 in metastatic colorectal cancer completed and re…
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer
A completed trial assessing cognitive/functional and long-term neurological effects of chemotherapy and radiation therapy in colorectal canc…
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: Validation Study of Linear Quantification of CD3+ Cells in Localized Colorectal Carcinomas
This update reports the completion of a validation study for linear quantification of CD3+ T cells in colorectal cancer tissues.
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Bovine Lactoferrin in Reducing Taste Disturbances in Patients With Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy [NA]
A completed clinical trial evaluating bovine lactoferrin to reduce taste disturbances in colorectal cancer patients receiving oxaliplatin-ba…
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FDA approval · 2018-07-02FDA Approved: CAPECITABINE — Original Application (Cipla USA Inc.)
FDA approved Cipla USA Inc.'s generic capecitabine under an Abbreviated New Drug Application (ANDA).
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Pilot Study in a Company in Maine-et-Loire to Evaluate the Feasibility, Acceptability, and Impact on the Participation Rate of Awareness of Colorectal Cancer Screening by Occupational Health Teams [NA]
A pilot study in a company in Maine-et-Loire aims to evaluate the feasibility, acceptability, and impact on participation in colorectal canc…
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CLINICAL_TRIALS withdrawal · 2018-07-02Clinical Trial Update: Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus) [Phase 1, Phase 2]
The NivoPlus trial evaluating nivolumab plus chemotherapy in various advanced cancers has been terminated (Phase 1/Phase 2).
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: F-18 FDG- PETCT in Staging and Recurrent Colorectal Cancer
Clinical trial update evaluating F-18 FDG-PET/CT for staging and detection of recurrence in colorectal cancer.
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: Ohio Colorectal Cancer Prevention Initiative [NA]
This is a clinical trial update for the Ohio Colorectal Cancer Prevention Initiative, investigating Lynch syndrome and colorectal cancer. Th…
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FDA approval · 2018-06-27FDA Approved: BRAFTOVI — Original Application (Array BioPharma Inc.)
FDA approved BRAFTOVI (encorafenib) under the original application (NDA210496) from Array BioPharma Inc., marking the drug's initial approva…
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: Perioperative vs Postoperative Chemotherapy + Bevacizumab in Colorectal Cancer, Liver Mets [Phase 2]
Phase 2 trial comparing perioperative versus postoperative chemotherapy with bevacizumab for colorectal cancer with liver metastases; study …
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CLINICAL_TRIALS research · 2018-06-26Clinical Trial Update: Evaluate the Efficacy of Irinotecan Versus Oxaliplatin in the First-line Treatment of Refractory Metastatic Colorectal Cancer [Phase 2]
A Phase 2 clinical trial comparing irinotecan to oxaliplatin as first-line therapy for refractory metastatic colorectal cancer; status is UN…
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Effectiveness of Gum Chewing on Ileus in Chinese Colorectal Patients Underwent Laparoscopic Colorectal Surgery [NA]
A completed clinical trial evaluated whether chewing gum reduces postoperative ileus in Chinese patients with colorectal cancer who underwen…
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CLINICAL_TRIALS trial_result · 2018-06-21Clinical Trial Update: Validation of MMS Test for Cancer Monitoring
Clinical trial validating the MMS Test for cancer monitoring has been terminated across multiple indications.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing
A clinical trial is evaluating whether microsatellite instability status in advanced colorectal cancer can be detected from blood using next…
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CLINICAL_TRIALS research · 2018-06-19Clinical Trial Update: Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study) [Phase 3]
Phase 3 clinical trial evaluating adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) versus no HIPEC in locally advanced colorectal …
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CLINICAL_TRIALS research · 2018-06-11Clinical Trial Update: Minimally Invasive Simultaneous Colorectal and Liver Surgery
A clinical trial investigating a minimally invasive approach for simultaneous colorectal and liver surgery in colorectal cancer patients. Th…
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CLINICAL_TRIALS trial_result · 2018-06-07Clinical Trial Update: Colonic Capsule Endoscopy (CCE) for Screening of Neoplasm's A Pilot Study [NA]
This update reports the completion of a pilot study evaluating Colonic Capsule Endoscopy (CCE) for screening colorectal neoplasms. The trial…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Study Using IMC-A12 (Cixutumumab) With or Without Cetuximab in Participants With Metastatic Colorectal Cancer Who Have Failed a Treatment Regimen That Consisted of a Prior Anti-EGFR Therapy [Phase 2]
Phase 2 trial evaluating IMC-A12 (cixutumumab) with or without cetuximab in metastatic colorectal cancer after prior anti-EGFR therapy; resu…
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CLINICAL_TRIALS withdrawal · 2018-06-06Clinical Trial Update: Study Comparing Pursestring Wound Closure vs Conventional Closure to Reverse Stoma of Colorectal Cancer Patients
A clinical trial comparing pursestring wound closure versus conventional closure for reversing a stoma in colorectal cancer patients is no l…
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FDA approval · 2018-06-05FDA Approved: ERBITUX — Supplemental Application (ImClone LLC)
The FDA approved a supplemental application for ERBITUX (cetuximab) filed by ImClone LLC.
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CLINICAL_TRIALS trial_result · 2018-05-31Clinical Trial Update: EGFR-IL12-CART Cells for Patients With Metastatic Colorectal Cancer [Phase 1]
Phase 1 clinical trial evaluating EGFR-IL12-CART cells in metastatic colorectal cancer. The study is sponsored by Shenzhen Second People's H…
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Pilot Study of the National Colorectal Cancer Roundtable Toolbox (NCCRT) to Increase Colorectal Cancer Screening Rates [NA]
This document reports the completion of a pilot study evaluating the National Colorectal Cancer Roundtable Toolbox (NCCRT) to increase color…