Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position [NA]
A completed clinical trial examining how neuromuscular blockade level and intra-abdominal pressure affect surgical conditions and cardiopulm…
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Safety and Efficacy of Anlotinib in Combination With Irinotecan in Patients With Pretreated Advanced Colorectal Cancer [Phase 1, Phase 2]
Clinical trial investigating safety and efficacy of anlotinib in combination with irinotecan in pretreated advanced colorectal cancer (Phase…
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CLINICAL_TRIALS trial_result · 2018-08-02Clinical Trial Update: ALPPS (Liver Partition and Portal Vein Ligation) for Two-stage Hepatectomy for Colorectal Liver Metastasis [Phase 3]
A Phase 3 trial evaluating ALPPS (liver partition and portal vein ligation) two-stage hepatectomy for colorectal liver metastasis has been t…
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: An Observational Study of First-Line Bevacizumab (Avastin) With Fluoropyrimidine-Based Chemotherapy in Participants With Metastatic Colorectal Cancer
This document reports the completion of an observational study evaluating first-line bevacizumab with fluoropyrimidine-based chemotherapy in…
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CLINICAL_TRIALS withdrawal · 2018-07-31Clinical Trial Update: A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Untreated Metastatic Colorectal Cancer. [Phase 2]
Phase 2 study of Avastin in combination with chemotherapy for previously untreated metastatic colorectal cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-07-31Clinical Trial Update: A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial is investigating cannabidiol for efficacy in multiple myeloma, glioblastoma, and various gastrointestinal cancers…
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CLINICAL_TRIALS research · 2018-07-31Clinical Trial Update: Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS [Phase 3]
Phase 3 trial update comparing peripheral parenteral nutrition to conventional fluids in colorectal resection under ERAS protocols.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer: Continued Avastin Plus Chemotherapy After First Progression in Clinical Practice
An observational study update evaluating whether continuing Avastin (bevacizumab) with chemotherapy after first progression is used in real-…
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Study on Cannabinoid Receptor Expression in Gastrointestinal Diseases
A completed clinical trial examined cannabinoid receptor expression in gastrointestinal diseases. The study covered ulcerative colitis, Croh…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Combination Chemotherapy After Surgery in Treating Patients With High-Risk Stage II or Stage III Colorectal Cancer [Phase 3]
This update reports the completion of a Phase 3 trial evaluating combination chemotherapy after surgery for high-risk stage II or stage III …
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FDA approval · 2018-07-27FDA Approved: LEUCOVORIN CALCIUM — Original Application (Fresenius Kabi USA, LLC)
FDA approved a generic Leucovorin Calcium under ANDA 207226 for Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS research · 2018-07-26Clinical Trial Update: New Genes in the Carcinogenesis of Colorectal Cancer
Clinical trial update exploring newly implicated genes in the carcinogenesis of colorectal cancer.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: A Trial of SHR-1210 in Combination With SHR6390 in Patients With Advanced CRC, NSCLC and HCC [Phase 1, Phase 2]
A clinical trial update for SHR-1210 in combination with SHR6390 in patients with advanced colorectal cancer, non-small cell lung cancer, an…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Flare Type Self-expandable Metal Stent for Malignant Colorectal Obstruction [NA]
A completed clinical trial evaluating a flare-type self-expandable metal stent for malignant colorectal obstruction associated with colorect…
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CLINICAL_TRIALS research · 2018-07-26Clinical Trial Update: A Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA
This study investigates a blood-based approach to early colorectal cancer detection by measuring 5-hydroxymethylcytosine in plasma cell-free…
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CLINICAL_TRIALS research · 2018-07-24Clinical Trial Update: The IMPETUS Cancer Trial. A Technology Delivered Physical Activity Intervention in Cancer [NA]
An update on the IMPETUS Cancer Trial, a technology-delivered physical activity intervention for cancer, enrolling in breast and colorectal …
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma [Phase 1]
Phase 1 study evaluating escalating doses of oxaliplatin with HIPEC in children and adolescents with extensive colorectal cancer; the trial …
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: The Effects of Mechnikov Probiotics on Symptom and Surgical Outcome [NA]
A completed clinical trial assessing the effects of Mechnikov Probiotics on symptoms and surgical outcomes in patients with sigmoid colon ca…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Lay Tel Compliance Study [NA]
Completed clinical trial from The Chinese University of Hong Kong studying patient compliance in colorectal cancer screening.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Effectiveness of Tel and SMS Reminder on Compliance With CRC Screening [NA]
A completed clinical trial from the Chinese University of Hong Kong evaluating whether telephone and SMS reminders improve adherence to colo…
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CLINICAL_TRIALS trial_result · 2018-07-16Clinical Trial Update: Hepatic Arterial Chemotherapy With Raltitrexed and Oxaliplatin Versus Standard Chemotherapy in Unresectable Liver Metastases From Colorectal Cancer After Conventional Chemotherapy Failure [Phase 2]
A Phase 2 randomized trial compares hepatic arterial chemotherapy with raltitrexed and oxaliplatin versus standard chemotherapy in patients …
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Safety Study of Regorafenib and SIR-Spheres® Microspheres Radioembolization in Patients With Refractory Metastatic Colorectal Cancer With Liver Metastases [Phase 2]
Phase 2 safety study evaluating regorafenib in combination with SIR-Spheres microspheres for refractory metastatic colorectal cancer with li…
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Systems Intervention to Promote Colorectal Cancer (CRC) Screening [NA]
This entry notes the completion of a clinical trial evaluating a systems-level intervention to promote colorectal cancer screening.
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors. [Phase 1]
Phase 1 clinical trial evaluating intravenously administered pegylated liposomal mitomycin-C lipid-based prodrug (PROMITIL) in cancer patien…
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors [Phase 1]
Phase 1 study of nintedanib plus bevacizumab in advanced solid tumors has completed, assessing safety and preliminary activity across severa…