Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts [Phase 3]
Phase 3 trial comparing modified XELOX plus cetuximab versus FOLFOX plus cetuximab in RAS/BRAF wild-type metastatic colorectal cancer; at pr…
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CLINICAL_TRIALS trial_result · 2021-10-08Clinical Trial Update: Study of Pembrolizumab in Combination With Chemotherapy for Patients With Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with chemotherapy for advanced colorectal cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-06Clinical Trial Update: LEAC-102 for Advanced Colorectal Cancer [Phase 1, Phase 2]
A clinical trial update for LEAC-102 in advanced colorectal cancer spanning Phase 1 and Phase 2, with current status unknown.
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CLINICAL_TRIALS trial_result · 2021-09-30Clinical Trial Update: Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 study results for INCB001158, an arginase inhibitor, as a single agent and in combination with immune checkpoint therapy, in patient…
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Study of Immune Response and Liver Damage Induced by Chemotherapy for Liver Metastases of Colorectal Cancer [Phase 2]
A Phase 2 clinical trial exploring immune response and chemotherapy-induced liver damage in patients with resectable hepatic metastases from…
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer [Phase 3]
Phase 3 trial comparing leucovorin and fluorouracil with or without oxaliplatin to capecitabine with or without oxaliplatin in metastatic co…
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: Cd133+ Cell Infusion in Patients With Colorectal Liver Metastases. [Phase 2]
Phase 2 clinical trial update on Cd133+ cell infusion in patients with colorectal liver metastases.
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CLINICAL_TRIALS trial_result · 2021-09-27Clinical Trial Update: mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases [Phase 3]
Phase 3 trial comparing mFOLFOXIRI+Bevacizumab versus mFOLFOX6+Bevacizumab in patients with RAS-mutant unresectable colorectal liver-limited…
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FDA approval · 2021-09-24FDA Approved: ERBITUX — Supplemental Application (ImClone LLC)
The FDA approved a supplemental application for Erbitux (cetuximab) submitted by ImClone LLC.
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: Combination Chemotherapy and Cetuximab as First-Line Therapy in Treating Patients With Advanced and/or Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating combination chemotherapy with cetuximab as first-line therapy for advanced/metastatic colorectal cancer has complet…
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CLINICAL_TRIALS trial_result · 2021-09-21Clinical Trial Update: Panitumumab and Irinotecan as Third-Line Therapy in Treating Patients With Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial investigating panitumumab with irinotecan as third-line therapy for metastatic colorectal cancer has completed with r…
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CLINICAL_TRIALS trial_result · 2021-09-20Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors [Phase 2]
Phase 2 trial evaluating TAK-931 in metastatic pancreatic cancer, colorectal cancer, and other advanced solid tumors has completed with post…
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CLINICAL_TRIALS trial_result · 2021-09-13Clinical Trial Update: Comparing Interventions to Increase Colorectal Cancer Screening [NA]
A completed clinical trial evaluating interventions to increase colorectal cancer screening; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Gemcitabine in Treating Patients With Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating gemcitabine in patients with advanced colorectal cancer has been completed.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients [Phase 2]
Phase 2 trial comparing CAPTEM to FOLFIRI as second-line treatment in metastatic colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Anlotinib Combined With mXELIRI as Second-line Treatment of Advanced Colorectal Cancer [Phase 1, Phase 2]
A clinical trial update investigates anlotinib combined with mXELIRI as second-line therapy for advanced colorectal cancer in Phase 1 and Ph…
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: PD-1 Inhibitor Combined With Bevacizumab and FOLFIRI Regimen in the Second-line Treatment of Advanced Colorectal Cancer [Phase 2]
Phase 2 trial updating the use of a PD-1 inhibitor in combination with bevacizumab and FOLFIRI for second-line advanced colorectal cancer wi…
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CLINICAL_TRIALS trial_result · 2021-08-30Clinical Trial Update: A Study of Bevacizumab Plus XELOX/XELIRI for First-line Treatment in Unresectable Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating bevacizumab with XELOX/XELIRI as first-line therapy for unresectable advanced colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-08-30Clinical Trial Update: Raltitrexed-based Chemotherapy Plus Bevacizumab in Retreated Patients With Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating raltitrexed-based chemotherapy plus bevacizumab in patients with advanced colorectal cancer who have been retreated…
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CLINICAL_TRIALS trial_result · 2021-08-30Clinical Trial Update: A Study of Cetuximab Plus Raltitrexed for Maintenance Treatment in Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating cetuximab plus raltitrexed as maintenance therapy in advanced colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer [Phase 2]
Phase 2 trial evaluating vascular disrupting agents or STAT3 inhibition to enhance PD-1 blockade in metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: The Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE) [Phase 2]
Phase 2 trial evaluating the combination of Fruquintinib, Tislelizumab, and stereotactic ablative radiotherapy in metastatic colorectal canc…
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CLINICAL_TRIALS trial_result · 2021-08-26Clinical Trial Update: A Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating lamivudine in patients with p53-mutant metastatic colorectal cancer has completed and posted results.
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: Prospective Study on the Efficacy and Safety of 2 Week or 3 Week Xelox Regimen for Adjuvant Chemotherapy in CRC [Phase 1, Phase 2]
Prospective Phase 1/2 trial assessing the efficacy and safety of a 2-week or 3-week Xelox regimen as adjuvant chemotherapy for colorectal ca…
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CLINICAL_TRIALS trial_result · 2021-08-24Clinical Trial Update: DS-8201a in Human Epidermal Growth Factor Receptor2 (HER2)-Expressing Colorectal Cancer (DESTINY-CRC01) [Phase 2]
Phase 2 trial update for DS-8201a (trastuzumab deruxtecan) in HER2-expressing colorectal cancer (DESTINY-CRC01) has completed with results p…