Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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FDA approval · 2021-12-15FDA Approved: OXALIPLATIN — Supplemental Application (Meitheal Pharmaceuticals Inc.)
FDA approved a supplemental application for Oxaliplatin by Meitheal Pharmaceuticals Inc.
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CLINICAL_TRIALS trial_result · 2021-12-14Clinical Trial Update: Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable) [Phase 2]
Phase 2 trial investigating regorafenib in combination with nivolumab for colorectal cancer (proficient mismatch repair and microsatellite s…
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CLINICAL_TRIALS trial_result · 2021-12-14Clinical Trial Update: Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer Survivors [Phase 2]
A Phase 2 pilot trial evaluated resistant starch in survivors of stage I-III colorectal cancer and is reported as terminated with results po…
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CLINICAL_TRIALS trial_result · 2021-12-09Clinical Trial Update: Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004 [Phase 2]
Phase 2 trial update evaluating standard of care with or without Ad-CEA vaccine and avelumab in previously untreated metastatic colorectal c…
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CLINICAL_TRIALS trial_result · 2021-12-07Clinical Trial Update: Follow-Up Care With or Without CEA Assessments in Patients Who Have Undergone Surgery for Stage II or Stage III Colorectal Cancer [Phase 3]
Phase 3 trial evaluating follow-up care with or without CEA assessments after surgery in stage II/III colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-12-06Clinical Trial Update: A Clincal Study of Max-40279-01 in Patients With Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial update for Max-40279-01 in metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-12-03Clinical Trial Update: Cetuximab and Pembrolizumab in Treating Patients With Colorectal Cancer That is Metastatic or Cannot Be Removed by Surgery [Phase 1, Phase 2]
Clinical trial evaluating cetuximab and pembrolizumab in metastatic or unresectable colorectal cancer has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-11-24Clinical Trial Update: A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation [Phase 1, Phase 2]
Phase 1/2 trial of LY3499446 in advanced solid tumors with KRAS G12C has been terminated; results posted in 2021.
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FDA approval · 2021-11-18FDA Approved: OXALIPLATIN — Supplemental Application (Sandoz Inc)
FDA approves the supplemental application for Oxaliplatin from Sandoz Inc. This action authorizes the changes described in the supplement to…
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FDA approval · 2021-11-17FDA Approved: OXALIPLATIN — Supplemental Application (Qilu Pharmaceutical Co., Ltd.)
FDA approved a supplemental application for oxaliplatin from Qilu Pharmaceutical Co., Ltd., confirming continued availability of the generic…
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CLINICAL_TRIALS trial_result · 2021-11-10Clinical Trial Update: MGD007 Combined With MGA012 in Relapsed/Refractory Metastatic Colorectal Cancer [Phase 1, Phase 2]
Phase 1/2 trial of MGD007 combined with MGA012 for relapsed/refractory metastatic colorectal cancer completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-11-04Clinical Trial Update: Surufatinib Combined With Sintilimab for Advanced MSS-Type Colorectal Cancer : a Phase II Study [Phase 2]
Phase II trial evaluating surufatinib in combination with sintilimab for advanced colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer [Phase 2]
A Phase 2 clinical trial evaluating Fruquintinib as maintenance therapy after first-line treatment for metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Innate Immune Homeostasis. [Phase 4]
A Phase 4 trial examining how low-pressure pneumoperitoneum during laparoscopic colorectal surgery affects innate immune homeostasis.
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: Study of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS Mutation [Phase 2]
Phase 2 trial evaluating binimetinib with nivolumab, with or without ipilimumab, in previously treated microsatellite-stable colorectal canc…
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CLINICAL_TRIALS trial_result · 2021-11-02Clinical Trial Update: Phase II Study Comparing Conversion Rate to Surgery With Hepatic Arterial Infusion Chemotherapy to Systemic Chemotherapy in Patients With Non Resectable Liver-only Colorectal Metastases [Phase 2]
Phase II study evaluating hepatic arterial infusion chemotherapy versus systemic chemotherapy for conversion to surgery in patients with non…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: BRAF/MEK/EGFR Inhibitor Combination Study in Colorectal Cancer (CRC) [Phase 1, Phase 2]
A phase 1/2 trial evaluating a BRAF/MEK/EGFR inhibitor combination in colorectal cancer has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer [Phase 3]
Phase III randomized trial comparing maintenance fluoropyrimidine ± bevacizumab versus fluoropyrimidine alone after induction chemotherapy i…
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CLINICAL_TRIALS research · 2021-10-28Clinical Trial Update: The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Early Quality of Recovery [Phase 4]
Phase 4 trial investigating the impact of low pressure pneumoperitoneum during laparoscopic colorectal surgery on early quality of recovery.
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Fruquintinib and Raltitrexed Versus Fruquintinib Monotherapy in Advanced Colorectal Cancer [Phase 2]
Phase 2 trial comparing Fruquintinib plus Raltitrexed versus Fruquintinib alone in advanced colorectal carcinoma.
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer [Phase 1, Phase 2]
Phase I/II trial investigating Pexa-Vec oncolytic virus in combination with immune checkpoint inhibitor for refractory colorectal cancer has…
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CLINICAL_TRIALS trial_result · 2021-10-25Clinical Trial Update: Trifluridine/Tipiracil Combined With Oxaliplatin and Bevacizumab Versus XELOX Plus Bevacizumab in mCRC [Phase 2]
Phase 2 trial comparing trifluridine/tipiracil combined with oxaliplatin and bevacizumab vs XELOX plus bevacizumab in first-line advanced co…
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CLINICAL_TRIALS trial_result · 2021-10-22Clinical Trial Update: PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC [Phase 2]
A Phase II trial evaluating panitumumab, nivolumab, and ipilimumab in Kras/NRAS/BRAF wild-type MSS metastatic colorectal cancer has complete…
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CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: Thymosin-alpha 1 for Adjuvant Treatment After Radical Resection of High-risk Stage II and III Colorectal Cancer [Phase 3]
Phase 3 clinical trial evaluating thymosin-alpha 1 as adjuvant treatment after radical resection for high-risk stage II and III colorectal c…
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CLINICAL_TRIALS trial_result · 2021-10-20Clinical Trial Update: A Clinical Study to Compare the Efficacy and Safety of AK105 Plus Anlotinib and Capecitabine/Oxaliplatin (CapeOx) , Anlotinib Plus CapeOx, Bevacizumab Plus CapeOx [Phase 2]
Phase 2 clinical trial comparing AK105 plus Anlotinib and CapeOx regimens in unresectable metastatic colorectal cancer; status currently UNK…