Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Prevention of Oxaliplatin-induced Nerve Damage in the Body's Extremities [NA]
A recruiting clinical trial aims to prevent oxaliplatin-induced peripheral neuropathy in colorectal cancer patients.
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CLINICAL_TRIALS withdrawal · 2026-04-03Clinical Trial Update: Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
The ECOG-ACRIN trial assessing biomarker testing practices for common solid cancers in community oncology settings has been withdrawn.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Clinical Study on the Expression of PHGDH and Its Prognostic Value in Colorectal Cancer Patients Receiving Immunotherapy
A completed clinical trial evaluated the expression of PHGDH and its potential prognostic value in colorectal cancer patients receiving immu…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of ZM008, an anti-LLT1 antibody, given as a single agent and then in combination with toripalimab in patients with ad…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer [Phase 2]
Clinical trial update describing a Phase 2 study of Linaclotide in patients with colorectal adenoma and colorectal cancer (stages 0–III), cu…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Pre-emptive Endoscopic Vacuum Therapy Reduces the Incidence of Anastomotic Leakage After Colorectal Cancer Surgery [NA]
The document reports a clinical trial investigating pre-emptive endoscopic vacuum therapy to reduce anastomotic leakage after colorectal can…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours [Phase 1]
Clinical trial update describes a Phase 1 dose-escalation study of [225Ac]-FPI-2068 in adults with advanced solid tumors, currently recruiti…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Personalized Health Self-Management Training for Colorectal Cancer Survivors [NA]
This clinical trial is investigating personalized health self-management training for colorectal cancer survivors and is currently recruitin…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities [NA]
A Mayo Clinic-sponsored clinical trial aims to address disparities in colorectal cancer screening among Black and underserved Phoenix commun…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating liposomal irinotecan with TAS-102 and bevacizumab for metastatic colorectal cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers [Phase 1]
This Phase 1 trial evaluates gevokizumab in combination with standard-of-care anticancer therapies for metastatic colorectal cancer, gastroe…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: The Role of Arginine in Oral Nutritional Supplementation in Preventing or Reducing Complications Following Colorectal Surgery in Patients Who Are Malnourished or at Risk of Malnutrition [NA]
A completed clinical trial evaluated whether adding arginine to an oral nutritional supplement reduces complications after colorectal surger…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Personalized T-Cell Therapy iNeo-Vac-T01 in Advanced Colorectal Cancer [Phase 1]
This is a Phase 1 clinical trial update for iNeo-Vac-T01, a personalized T-cell therapy, in patients with metastatic colorectal cancer. The …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC [Phase 2]
Ongoing phase 2 trial evaluating enfortumab vedotin in advanced or metastatic colorectal cancer and hepatocellular carcinoma; study is curre…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors [Phase 1, Phase 2]
Revolution Medicines is conducting a Phase 1/2 clinical trial of RAS(ON) inhibitors in gastrointestinal solid tumors, including colorectal c…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer [Phase 2]
Open-label Phase 2 study evaluating the combination of Avutometinib, Defactinib, and Cetuximab in unresectable, anti-EGFR-refractory advance…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Screen to Save: NCI Colorectal Cancer Outreach & Screening Initiative [NA]
The NCT05064410 clinical trial 'Screen to Save: NCI Colorectal Cancer Outreach & Screening Initiative' has completed.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Anastomotic Bleeding in Colorectal Anastomosis Relating to the Placement of the Stapler Spike to the Staple Line
A clinical trial is investigating whether the placement of the stapler spike relative to the staple line during colorectal anastomosis affec…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia. [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled study assessing NGM120 in colorectal cancer patients with cancer cachexia is currentl…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing Pumitamig plus chemotherapy to Bevacizumab plus chemotherapy in previously untreated, unresectable, or …
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Safety and Efficacy of Neoantigen-Based Personalized Immunotherapy as Consolidation Therapy After Standard Adjuvant Treatment in Resectable Stage III Colorectal Cancer or Non-Small Cell Lung Cancer [Phase 1]
This Phase 1 trial update reports on the safety and efficacy of a neoantigen-based personalized immunotherapy used as consolidation therapy …
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer [Phase 2]
This update describes a Phase 2 trial evaluating the combination of cabozantinib and nivolumab for refractory metastatic microsatellite-stab…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Umbrella Trial of Neoadjuvant Therapy for Locally Advanced Colorectal Cancer [Phase 2]
Phase 2 umbrella trial evaluating neoadjuvant therapy for locally advanced colorectal cancer; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types [Phase 1]
IDEAYA Biosciences is conducting a Phase 1 study of IDE034 in adults with multiple locally advanced or metastatic solid tumors; the trial is…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours [Phase 1, Phase 2]
Ipsen is conducting a Phase 1/2 trial of IPN01194 as a single-agent therapy for adults with advanced solid tumors, currently recruiting.