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CLINICAL_TRIALS research · 2026-04-01

Clinical Trial Update: Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer [Phase 2]

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Summary

Open-label Phase 2 study evaluating the combination of Avutometinib, Defactinib, and Cetuximab in unresectable, anti-EGFR-refractory advanced colorectal cancer …

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Diseases / indications

Drugs mentioned

  • Avutometinib (avutometinib)
  • Cetuximab (cetuximab)
  • Defactinib (defactinib)

Snippet

Sponsor: M.D. Anderson Cancer Center | Conditions: Advanced Colorectal Cancer | Phase 2 | Status: RECRUITING