Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: Study of HL-085 and Vemurafinib in Metastatic Colorectal Cancer (mCRC) [Phase 2]
A Phase 2 clinical trial investigating HL-085 in combination with Vemurafinib for metastatic colorectal cancer is ongoing, with the status c…
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CLINICAL_TRIALS trial_result · 2023-05-26Clinical Trial Update: QL1203 In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy and Safety [Phase 3]
Phase 3 trial investigating QL1203 in combination with chemotherapy for metastatic colorectal cancer to evaluate efficacy and safety.
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CLINICAL_TRIALS trial_result · 2023-05-25Clinical Trial Update: QL1706 Monotherapy or in Combination With Bevacizumab and XELOX as First-line Treatment of Unresectable Advanced or Metastatic CRC [Phase 2]
A Phase 2 trial update for QL1706 monotherapy or in combination with bevacizumab and XELOX as first-line treatment in unresectable advanced …
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients [Phase 3]
Phase 3 trial evaluating adjuvant chemotherapy with or without targeted therapy in T3-4N2 colorectal cancer patients is ongoing.
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Effect of Lidocaine Transdermal Patch as Add-On Therapy in Treatment of Oxaliplatin Induced Peripheral Neuropathy in Colorectal Cancer Patients [Phase 2]
Phase 2 clinical trial evaluating a lidocaine transdermal patch as add-on therapy for oxaliplatin-induced peripheral neuropathy in colorecta…
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CLINICAL_TRIALS trial_result · 2023-05-17Clinical Trial Update: COLLISION RELAPSE Trial [Phase 3]
Phase 3 clinical trial update for COLLISION RELAPSE investigating colorectal cancer with liver metastases; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-05-17Clinical Trial Update: Adjuvant Durvalumab Plus Regorafenib vs Untreated Control in Stage IV Colorectal Cancer Patients With no Evidence of Disease (NED): VIVA Trial [Phase 2]
Phase 2 trial evaluating adjuvant durvalumab plus regorafenib versus no treatment in stage IV colorectal cancer patients with no evidence of…
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FDA approval · 2023-05-15FDA Approved: IRINOTECAN HYDROCHLORIDE — Supplemental Application (Hospira, Inc.)
FDA approves Hospira's supplemental application for irinotecan hydrochloride (ANDA 077915), enabling the marketed generic product. This acti…
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CLINICAL_TRIALS trial_result · 2023-04-28Clinical Trial Update: A Phase II Study on Dose Optimization of Fruquintinib in Elderly mCRC Patients Refractory to Standard Treatment（DOFEMCRC） [Phase 2]
Phase II study evaluating dose optimization of Fruquintinib in elderly colorectal cancer patients refractory to standard treatment has compl…
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204) [Phase 1, Phase 2]
Phase 1/2 study evaluating Epacadostat in combination with Nivolumab in select advanced cancers; results have been posted following completi…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer [NA]
Clinical trial update for M5A, a Copper-64 labeled anti-CEA monoclonal antibody used in PET imaging to diagnose CEA-positive cancers; the st…
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer [Phase 2]
Phase 2 trial of tucatinib plus trastuzumab in HER2-positive metastatic colorectal cancer has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Safety and Efficacy of CEA-Targeted CAR-T Therapy for Relapsed/Refractory CEA+ Cancer [Phase 1, Phase 2]
Early-phase trial update on a CEA-targeted CAR-T therapy for relapsed/refractory CEA-positive solid tumors, including lung and colorectal ca…
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: Cadonilimab in Locally Advanced MSI-H/dMMR Colorectal Cancer [Phase 2]
Phase 2 clinical trial update for cadonilimab in locally advanced MSI-H/dMMR colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-04-18Clinical Trial Update: ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer [Phase 3]
A Phase 3 trial is exploring ctDNA-guided adjuvant chemotherapy for liver metastases arising from colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen [Phase 2]
Phase 2 trial evaluating FOLFIRI-aflibercept vs initial FOLFIRI-aflibercept followed by maintenance 5FU-aflibercept in elderly patients with…
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Safety and Efficacy Study of XELOX vs. Oxaliplatin+5-FU CI as First Line Treatment in Metastatic Colorectal Cancer [Phase 3]
Phase 3 trial comparing XELOX to oxaliplatin plus 5-FU as first-line therapy in metastatic colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Optimization of Bevacizumab Scheduling With Chemotherapy for Metastatic Colorectal Cancer [Phase 3]
Phase 3 clinical trial update on optimizing bevacizumab scheduling with chemotherapy for metastatic colorectal cancer completed; results pos…
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Efficacy and Safety of SBRT Followed by Tislelizumab Plus Cetuximab and Irinotecan in Patients With Previously Treated RAS Wild-type Advanced Refractory Colorectal Cancer [Phase 2]
Phase 2 trial evaluating SBRT followed by tislelizumab plus cetuximab and irinotecan in previously treated RAS wild-type advanced refractory…
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Comparing Efficacy and Safety of Cetuximab (CinnaGen) Versus Erbitux® (Merck) in Metastatic Colorectal Cancer [Phase 3]
Phase 3 trial update comparing cetuximab from Cinnagen with Erbitux in metastatic colorectal cancer; current status unknown.
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA [Phase 3]
Phase 3 trial evaluating post-operative maintenance therapy for resectable liver metastases from colorectal cancer guided by ctDNA; currentl…
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: FOLFOX/FOLFIRI Containing Levofolinic Acid (Zuoyu ®) in the Treatment of Unresectable or Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial update for a FOLFOX/FOLFIRI regimen containing Levofolinic Acid (Zuoyu) in unresectable or metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-03-31Clinical Trial Update: Tislelizumab Plus Cetuximab and Irinotecan vs Third-line Standard-of-care in Refractory mCRC [Phase 2]
Phase 2 trial evaluating tislelizumab plus cetuximab and irinotecan versus third-line standard-of-care in refractory metastatic colorectal c…
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CLINICAL_TRIALS trial_result · 2023-03-28Clinical Trial Update: Phase II Study of Tislelizumab Combined With Cetuximab and Irinotecan in the Treatment of Recurrent, Refractory mCRC [Phase 2]
Phase II study evaluating tislelizumab combined with cetuximab and irinotecan for recurrent, refractory metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal Cancer [Phase 2]
Phase 2 trial evaluating regorafenib monotherapy as second-line treatment for patients with RAS-mutant advanced colorectal cancer.