Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101) [Phase 1, Phase 2]
Clinical trial update for KVA12123 as a standalone and in combination with pembrolizumab in advanced solid tumors; current status is unknown…
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers [Phase 2]
Phase 2 clinical trial evaluating nivolumab with tadalafil and oral vancomycin in patients with refractory hepatocellular carcinoma or liver…
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FDA approval · 2023-07-10FDA Approved: CAPECITABINE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA approved a supplemental application for capecitabine from Teva Pharmaceuticals USA, Inc., indicating an update to its labeling or in…
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CLINICAL_TRIALS trial_result · 2023-07-07Clinical Trial Update: A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer [Phase 2]
Phase 2 clinical trial evaluating ONM-100 as an intraoperative fluorescence imaging agent for cancer detection has completed enrollment with…
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CAN04 in combination with various chemotherapy regimens for advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer [Phase 3]
A Phase 3 trial evaluating intravenous vitamin C in combination with chemotherapy in advanced colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-06-26Clinical Trial Update: Trial of Aspirin and Arginine Restriction in Colorectal Cancer [Phase 2]
Phase 2 trial investigating aspirin and arginine restriction in colorectal cancer has completed with results posted.
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FDA approval · 2023-06-23FDA Approved: OXALIPLATIN — Supplemental Application (Winthrop U.S, a business of sanofi-aventis U.S. LLC)
FDA approved a supplemental application for oxaliplatin, submitted by Winthrop U.S., a business of sanofi-aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer [Phase 2]
A Phase 2 clinical trial assessing cadonilimab as neoadjuvant therapy for resectable stage II-III colorectal cancer with MSI-H/dMMR.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed [Phase 2]
A Phase 2 clinical trial evaluating high-dose folic acid to prevent colorectal cancer recurrence in patients who had polyps surgically remov…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Octreotide Compared With Loperamide Hydrochloride for Chemotherapy-Related Diarrhea in Patients With Colorectal Cancer [Phase 3]
Phase 3 trial comparing octreotide to loperamide for chemotherapy-related diarrhea in colorectal cancer patients has completed.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Study of Durvalumab (MEDI4736) (Anti-PD-L1) and Trametinib (MEKi) in MSS Metastatic Colon Cancer [Phase 2]
Phase 2 trial evaluating durvalumab plus trametinib in metastatic MSS colorectal cancer completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer [Phase 1, Phase 2]
A Phase 1/2 study evaluated the combination of copanlisib, a PI3K inhibitor, with nivolumab in relapsed/refractory microsatellite-stable sol…
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating fluorouracil-uracil and leucovorin in elderly patients with metastatic colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: FOLFOXIRI With or Without Panitumumab in Metastatic Colorectal Cancer (VOLFI) [Phase 2]
Phase 2 trial assessing FOLFOXIRI with or without panitumumab in metastatic colorectal cancer completed.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Maintenance Therapy With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction and Re-induction After Progress for 1st-line Treatment of Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial evaluating maintenance therapy with 5-FU/FA plus panitumumab versus 5-FU/FA alone after induction/re-induction in first-line m…
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer [Phase 2]
Phase 2 clinical trial updating cryosurgery for unresectable liver metastases from colorectal cancer; completed study.
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CLINICAL_TRIALS trial_result · 2023-06-13Clinical Trial Update: Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Colorectal Surgery [Phase 4]
Phase 4 trial evaluating topical antibiotic therapy to prevent incisional surgical infection after colorectal surgery has been completed.
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: Cetuximab as Salvage Therapy in Patients With Neo Wild-type RAS/RAF Metastatic Colorectal Cancer With Liver Metastases. [Phase 2]
Phase 2 trial evaluating cetuximab as salvage therapy in patients with wild-type RAS/RAF metastatic colorectal cancer with liver metastases.
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis [Phase 2]
Phase 2 trial comparing CRS-HIPEC using mitomycin-C vs. melphalan for colorectal peritoneal carcinomatosis (appendiceal/colorectal cancers).
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC) [Phase 2]
Phase 2 trial of VB-111 in combination with nivolumab for metastatic colorectal cancer was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: Clinical Study on the Effect of Brucea Javanica Oil Emulsion Injection on the Survival of Patients With Advanced Colorectal Cancer Who Failed to Receive Multi-line Treatment [Phase 4]
Phase 4 clinical trial investigating Brucea javanica oil emulsion injection in advanced colorectal cancer patients after multi-line therapy …
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: Serplulimab+Regorafenib +Hepatic Artery Bicarbonate Infusion in Patients With Colorectal Cancer and Liver Metastases [Phase 2]
A Phase 2 clinical trial evaluating serplulimab combined with regorafenib and hepatic artery bicarbonate infusion for colorectal cancer with…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: SALIRI Based Regimen as First-line Treatment for Advanced Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial update evaluating a SALIRI-based regimen as first-line treatment for advanced metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE) [Phase 2]
Phase 2 clinical trial update evaluating omega-3 fatty acids for colorectal cancer prevention in patients with Lynch syndrome.