Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: RC48-ADC Combined With Bevacizumab in HER2-positive Advanced Colorectal Cancer [Phase 2]
Phase 2 clinical trial update investigating RC48-ADC in combination with bevacizumab for HER2-positive advanced colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver [Phase 2]
A Phase 2 trial examining isolated hepatic perfusion with melphalan followed by chemotherapy in patients with unresectable colorectal cancer…
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Alpelisib and Capecitabine in Patients With PIK3CA Mutant mCRC Patients [Phase 1, Phase 2]
Clinical trial update on alpelisib plus capecitabine in PIK3CA-mutant metastatic colorectal cancer (Phase 1/2).
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer [Phase 3]
Phase 3 trial comparing arfolitixorin with leucovorin in combination with FOLFOX and bevacizumab for advanced colorectal cancer has complete…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: TWICE-IRI: Optimization of Second-line Therapy With Aflibercept, Irinotecan (Day 1 or Day 1,3), 5-Fluorouracile and Folinic Acid in Patients With Metastatic Colorectal Cancer. A Randomized Phase III Study. [Phase 3]
A randomized Phase III trial evaluating second-line therapy with aflibercept, irinotecan (Day 1 or Day 1,3), 5-fluorouracil, and folinic aci…
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FDA approval · 2023-10-23FDA Approved: CAPECITABINE — Original Application (Teyro Labs Private Limited)
FDA approved the original application (ANDA) for a generic capecitabine product manufactured by Teyro Labs Private Limited.
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: A Study of JMT101 in Patients With Metastatic Colorectal Cancer [Phase 2]
A Phase 2 clinical trial update for JMT101 in patients with metastatic colorectal cancer is currently listed as unknown status.
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: Impact of Intravenous Lidocaine During Colorectal Surgery on Pain and Immune Functions [Phase 4]
A Phase 4 clinical trial evaluating intravenous lidocaine during colorectal surgery for its effects on pain and immune function.
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: Study Evaluating the Influence of LV5FU2 Bevacizumab Plus Anakinra Association on Metastatic Colorectal Cancer [Phase 2]
A Phase 2 trial assessing the combination of LV5FU2, bevacizumab, and anakinra for metastatic colorectal cancer has completed enrollment.
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: PD-1 Antibody Combined With COX Inhibitor in MSI-H/dMMR or High TMB Colorectal Cancer [Phase 2]
Phase 2 trial investigating a PD-1 antibody in combination with a COX inhibitor for MSI-H/dMMR or high tumor mutational burden colorectal ca…
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer [NA]
A completed trial evaluated whether fiber and fish oil supplements prevent colorectal cancer in healthy adults, with results posted in Octob…
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: FOLFOXIRI + Bev + Atezo vs FOLFOXIRI + Bev as First-line Treatment of Unresectable Metastatic Colorectal Cancer Patients [Phase 2]
Phase 2 trial comparing FOLFOXIRI + Bevacizumab + Atezolizumab versus FOLFOXIRI + Bevacizumab as first-line therapy for unresectable metasta…
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FDA approval · 2023-10-11FDA Approved: BRAFTOVI — Supplemental Application (Array BioPharma Inc.)
The FDA approved a supplemental application for BRAFTOVI (encorafenib) submitted by Array BioPharma Inc., updating the drug's labeling or in…
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: Envafolimab Combined With Trifluridine/Tipiracil and Bevacizumab in the Treatment of Refractory mCRC. [Phase 2]
Phase 2 trial update evaluating envafolimab in combination with trifluridine/tipiracil and bevacizumab for refractory metastatic colorectal …
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC [Phase 2]
Phase 2 trial update for LUT014 aiming to reduce acneiform lesions caused by EGFR inhibitors in metastatic colorectal cancer patients.
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: TheraSphere® For Treatment of Metastases in Liver [NA]
Clinical trial update for TheraSphere in liver metastases from colorectal cancer; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-02Clinical Trial Update: Rural Interventions for Screening Effectiveness [NA]
Completed clinical trial evaluating rural interventions to improve screening effectiveness for breast, cervical, or colorectal cancer; resul…
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Combination Chemotherapy for 3 Months or 6 Months in Treating Patients With Stage III Colon Cancer [Phase 3]
A Phase 3 clinical trial evaluating 3 months vs 6 months of combination chemotherapy in stage III colorectal cancer (colon cancer).
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Clinical Trial to Evaluate Safety and Efficacy of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) With Mitomycin C Used During Surgery for Treatment of Locally Advanced Colorectal Carcinoma [Phase 3]
Phase 3 clinical trial evaluating safety and efficacy of hyperthermic intraperitoneal chemotherapy with mitomycin C during surgery for local…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors [Phase 2]
Phase 2 trial update evaluating high-dose vitamin C with metformin for malignant tumors including hepatocellular and pancreatic cancer.
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Nitazoxanide in Patients With Metastatic Colorectal Cancer [Phase 3]
A Phase 3 trial evaluating nitazoxanide in patients with metastatic colorectal cancer is underway or planned; no results or status are provi…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Phase 2 Study of CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Relapsed and/or Refractory Metastatic Colorectal Cancer [Phase 2]
Phase 2 study comparing CA102N plus TAS-102 to bevacizumab plus TAS-102 in relapsed/refractory metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer [Phase 3]
Phase 3 trial results evaluate the efficacy and safety of Fruquintinib (HMPL-013) in metastatic colorectal/colon cancer, with results posted…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens [Phase 1, Phase 2]
Phase 1/2 trial update of a personalized cancer vaccine targeting shared neoantigens for solid tumors including non-small cell lung cancer a…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: A Study of a Personalized Neoantigen Cancer Vaccine [Phase 1, Phase 2]
Clinical trial update for a personalized neoantigen cancer vaccine completed across Phase 1 and Phase 2.