Cocaine Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Pharmacotherapy and Intensive Treatment - 2 [Phase 4]
A Phase 4 clinical trial evaluating pharmacotherapy and intensive treatment for cocaine use disorder and other substance use disorders has c…
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: Pathophysiological Subtyping of Abnormalities in Cocaine Dependence - 9 [Phase 4]
Phase 4 trial investigating pathophysiological subtypes in cocaine use disorder has completed. The study also involves related substance use…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse [Phase 1]
This ClinicalTrials.gov update notes the Phase 1 study on combined behavioral and pharmacologic treatment for polydrug abuse (opioid use dis…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Relapse Patterns in Female Cocaine Users - 4
Completed clinical trial evaluating relapse patterns in female individuals with cocaine use disorder.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Modeling Impaired Judgement in Cocaine Abusers - 6 [Phase 4]
NIDA conducted a Phase 4 study to model impaired judgement in individuals with cocaine use disorder, which has completed.
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1 [Phase 1]
Phase 1 clinical trial update on human dopamine transporter imaging for cocaine use disorder; study completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1 [Phase 2]
This update reports the completion of a Phase 2 clinical trial evaluating the combination of disulfiram and naltrexone for treating individu…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Cocaine-Methylphendidate Interaction Study - 4 [Phase 1]
Phase 1 study completed to evaluate the interaction between cocaine and methylphenidate.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Prepulse Inhibition of Startle in Cocaine Dependence - 7 [Phase 1]
A Phase 1 clinical trial update from NIDA evaluating prepulse inhibition of startle in cocaine use disorder, with the study (NCT00015249) no…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine [Phase 2]
Phase 2 trial evaluating whether GABA agonists can reduce the reinforcing effects of cocaine in individuals with cocaine-use disorders; the …
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin [Phase 1]
A Phase 1 study completed to evaluate potential pharmacokinetic and safety interactions between intravenous cocaine and oral lorcaserin.
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Interaction Between Cocaine and Quetiapine - 1 [Phase 1]
This Phase 1 trial investigates the interaction between cocaine use and quetiapine in individuals with cocaine use disorder; current status …
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Infusion Laboratory: Protocol 4 (Dihydrexidine) - 13 [Phase 1]
Phase 1 clinical trial update involving dihydrexidine for cocaine use disorder; the current study status is UNKNOWN.
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1 [Phase 1]
Phase 1 clinical trial (NCT00094315) sponsored by NIDA to develop a human laboratory model for cocaine relapse prevention.
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CLINICAL_TRIALS research · 2017-01-11Clinical Trial Update: Interactions Between Cocaine and Ethanol and Disulfiram - 1 [Phase 1]
Phase 1 clinical trial update examining interactions between cocaine, ethanol (alcohol), and disulfiram, sponsored by the National Institute…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Progesterone for Postpartum Cocaine Relapse [NA]
This clinical trial evaluates progesterone for preventing postpartum relapse to cocaine use. The study is completed and results have been po…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: FMRI of Stress and Addictive Disorders
A completed Yale University study used functional MRI to examine brain responses to stress in individuals with cocaine use disorder, opioid …
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CLINICAL_TRIALS trial_result · 2016-10-06Clinical Trial Update: n-Acetylcysteine and Cocaine [EARLY_Phase 1]
Phase 1 clinical trial assessing n-acetylcysteine for cocaine use disorder has completed; results were posted in October 2016.
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Phendimetrazine and Cocaine [EARLY_Phase 1]
Early Phase 1 clinical trial update on phendimetrazine for cocaine use disorder; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Conflict Between Maternal Autonomy and Child Health in Substance-use
This completed clinical trial update examines the balance between maternal autonomy and neonatal health in the setting of substance use duri…
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CLINICAL_TRIALS research · 2016-09-08Clinical Trial Update: Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction. [NA]
This clinical trial update discusses using deep brain stimulation of the sub-thalamic nucleus to treat severe and treatment-resistant cocain…
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CLINICAL_TRIALS withdrawal · 2016-09-08Clinical Trial Update: Assessing the Impact of Varenicline on Brain-Behavior Vulnerability [Phase 2]
Phase 2 trial evaluating varenicline for reducing brain-behavior vulnerability to cocaine cues has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence
A completed clinical trial evaluating the effects of corticorelin on dopamine transmission, craving, and mood in cocaine use disorder.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001) [Phase 1]
Phase 1 rising-dose study evaluating the safety and pharmacokinetics of EMB-001, a metyrapone/oxazepam combination, in individuals with coca…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4 [Phase 2]
Phase 2 trial update reporting completion of a study evaluating amantadine for cocaine use disorder.