Cocaine Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Progesterone for Postpartum Cocaine Relapse [NA]
This clinical trial evaluates progesterone for preventing postpartum relapse to cocaine use. The study is completed and results have been po…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: FMRI of Stress and Addictive Disorders
A completed Yale University study used functional MRI to examine brain responses to stress in individuals with cocaine use disorder, opioid …
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CLINICAL_TRIALS trial_result · 2016-10-06Clinical Trial Update: n-Acetylcysteine and Cocaine [EARLY_Phase 1]
Phase 1 clinical trial assessing n-acetylcysteine for cocaine use disorder has completed; results were posted in October 2016.
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Phendimetrazine and Cocaine [EARLY_Phase 1]
Early Phase 1 clinical trial update on phendimetrazine for cocaine use disorder; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: Conflict Between Maternal Autonomy and Child Health in Substance-use
This completed clinical trial update examines the balance between maternal autonomy and neonatal health in the setting of substance use duri…
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence
A completed clinical trial evaluating the effects of corticorelin on dopamine transmission, craving, and mood in cocaine use disorder.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001) [Phase 1]
Phase 1 rising-dose study evaluating the safety and pharmacokinetics of EMB-001, a metyrapone/oxazepam combination, in individuals with coca…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4 [Phase 2]
Phase 2 trial update reporting completion of a study evaluating amantadine for cocaine use disorder.
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Vigabatrin for the Treatment of Cocaine Dependency [Phase 2, Phase 3]
The document reports Phase 2 and Phase 3 trials evaluating vigabatrin for cocaine use disorder, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: Impact of Buspirone Maintenance on the Reinforcing Effects of Cocaine [NA]
This completed clinical trial assessed whether buspirone maintenance reduces the reinforcing effects of cocaine in individuals with cocaine …
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence [Phase 2]
Phase 2 clinical trial evaluated behavioral therapy plus carbidopa/levodopa for cocaine use disorder and has completed. The document does no…
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CLINICAL_TRIALS trial_result · 2015-11-05Clinical Trial Update: Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects [Phase 2]
Phase 2 clinical trial update reporting on the efficacy and safety of TV-1380 as a treatment to facilitate abstinence in cocaine use disorde…
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1 [Phase 3]
A Phase 3 clinical trial sponsored by the University of Pennsylvania evaluating naltrexone in two psychosocial treatment models for alcohol …
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: Nefazodone in the Treatment of Cocaine Dependence and Depression - 4 [Phase 2]
Phase 2 clinical trial of nefazodone for cocaine dependence with comorbid depression has completed (sponsor: Boston Medical Center).
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: Combined Buprenorphine and Behavioral Treatment With and Without Contingent Reinforcement on Opioid and Cocaine Abstinence. - 22 [Phase 2]
A Phase 2 study evaluated whether adding contingent reinforcement to buprenorphine-based behavioral treatment improves opioid and cocaine ab…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Carbamazepine Treatment for Cocaine Dependence - 5 [Phase 2]
A Phase 2 trial at the University of Pennsylvania evaluated carbamazepine for cocaine use disorder and has completed.
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Selegiline in Treatment of Cocaine Dependence - 2 [Phase 2]
A Phase 2 trial evaluating selegiline for cocaine use disorder has completed; the update notes the study status but does not include outcome…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Gepirone vs Placebo in Treatment of Cocaine Dependence - 3 [Phase 2]
Phase 2 trial comparing gepirone to placebo for cocaine use disorder has completed; the summary does not include results.
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Ritanserin in Treatment of Cocaine Dependence - 1 [Phase 2]
This entry reports the completion of a Phase 2 trial evaluating ritanserin for cocaine use disorder, sponsored by the University of Pennsylv…
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CLINICAL_TRIALS trial_result · 2015-04-16Clinical Trial Update: Pharmacotherapy and Intensive Treatment of Drug Abuse - 1 [Phase 2]
A Phase 2 clinical trial evaluating pharmacotherapy and intensive treatment for cocaine-use disorder and other substance use disorders has c…
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CLINICAL_TRIALS trial_result · 2015-01-27Clinical Trial Update: Rivastigmine and Huperzine A as Treatments for Cocaine Dependence [Phase 1]
This Phase 1 trial evaluated rivastigmine and huperzine A as potential treatments for cocaine use disorder, and the study status is complete…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: CBT With Disulfiram and Contingency Management [Phase 1]
Phase 1 trial evaluating cognitive behavioral therapy with disulfiram and contingency management for cocaine use disorder has completed with…
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CLINICAL_TRIALS trial_result · 2014-08-11Clinical Trial Update: Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/Dependence [Phase 3]
A Phase 3 trial evaluating citicoline therapy in mania/hypomania with cocaine use disorder has completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: Quetiapine for the Reduction of Cocaine Use [NA]
This clinical trial update reports completion of a study evaluating quetiapine for reducing cocaine use, with results posted in February 201…
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Combined Donepezil and Selegiline Effects on Cocaine-Reinforced Behavior [Phase 2]
Phase 2 study evaluating the effects of combining donepezil and selegiline on cocaine-reinforced behavior in cocaine use disorder has comple…