Cocaine Dependence
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: Use of Donepezil for Treatment of Cocaine Dependence [Phase 2]
A Phase 2 clinical trial examined donepezil for the treatment of cocaine dependence; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: Progesterone Treatment for Cocaine-dependent Women: A Pilot Study [Phase 2, Phase 3]
This clinical trial update reports results from a Phase 2/3 pilot study evaluating progesterone treatment for cocaine-dependent women; the s…
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: Sex Differences in Progesterone Effects on Responses to Stress and Drug Cues [Phase 1]
Phase 1 trial update examining whether progesterone modulates stress- and cocaine cue–induced responses in individuals with cocaine dependen…
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CLINICAL_TRIALS trial_result · 2014-02-05Clinical Trial Update: Effect of Oxytocin on Stress Response in Cocaine-dependent Individuals [Phase 2]
A Phase 2 clinical trial evaluated whether oxytocin modulates stress response in individuals with cocaine dependence. The trial has complete…
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior [Phase 2]
Phase 2 clinical trial evaluating modafinil for cocaine dependence with HIV high-risk behavior; results have been posted.
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: VIVITROL as a Treatment for Cocaine and Alcohol Dependence [Phase 2]
Phase 2 trial update for VIVITROL in cocaine and alcohol dependence; study completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-12-31Clinical Trial Update: Pilot Trial of Acamprosate for the Treatment of Cocaine Dependence [Phase 2]
Phase 2 pilot trial evaluating acamprosate for cocaine dependence has completed with results posted.
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Disulfiram for Cocaine Abuse [Phase 2]
A Phase 2 clinical trial evaluating disulfiram for cocaine dependence has completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-11-07Clinical Trial Update: Chantix for Treating Cocaine Dependence [Phase 2]
Phase 2 trial evaluating Chantix (varenicline) for cocaine dependence has completed and posted results.
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CLINICAL_TRIALS trial_result · 2013-09-26Clinical Trial Update: Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency [Phase 4]
Phase 4 trial evaluating lamotrigine as add-on therapy for bipolar disorder and cocaine dependence; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-04-16Clinical Trial Update: Exercise as an Adjunctive Treatment for Cocaine Dependent Patients [NA]
This update reports the completion of a clinical trial evaluating exercise as an adjunctive treatment for cocaine dependence. The study inve…
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CLINICAL_TRIALS trial_result · 2013-04-11Clinical Trial Update: Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction [Phase 3]
Phase 3 brain imaging trial evaluating the effects of modafinil in cocaine addiction has completed.
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: A Placebo-Controlled Study of Mixed Amphetamine Salts and Topiramate for the Treatment of Cocaine Dependence [Phase 2]
Phase 2 placebo-controlled trial evaluating mixed amphetamine salts plus topiramate for cocaine dependence has completed with results posted…
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CLINICAL_TRIALS trial_result · 2012-12-28Clinical Trial Update: Pharmacogenetics of Disulfiram for Cocaine [Phase 2]
Phase 2 clinical trial evaluating the pharmacogenetics of disulfiram for cocaine dependence. The study included opioid dependence as a co-oc…
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial [Phase 2]
A Phase 2 pilot trial evaluated atomoxetine for cocaine dependence; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence [Phase 2]
This Phase 2, placebo-controlled, double-blind trial evaluated modafinil plus cognitive-behavioral therapy for cocaine dependence; the study…
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Beta-blockade Effects on Memory for Cocaine Craving [Phase 2]
Phase 2 trial investigating whether beta-blockade affects memory for cocaine craving in people with cocaine dependence. Results were posted …
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CLINICAL_TRIALS trial_result · 2012-09-07Clinical Trial Update: A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence [Phase 2]
This clinical trial update reports a Phase 2 double-blind, controlled study of aripiprazole in patients with co-morbid schizophrenia and coc…
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CLINICAL_TRIALS trial_result · 2012-09-06Clinical Trial Update: Modafinil, Sleep, and Cognition in Cocaine Dependence [NA]
A completed Yale-led clinical trial evaluated modafinil for sleep and cognitive outcomes in cocaine dependence; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence [Phase 4]
A Phase 4 add-on trial evaluated quetiapine for patients with bipolar disorder who also have cocaine dependence, and the study has completed…
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CLINICAL_TRIALS trial_result · 2012-07-27Clinical Trial Update: A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence [Phase 1]
This Phase 1 pilot study evaluated cabergoline as a treatment for cocaine dependence; the study status is completed.
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Vigabatrin for Treatment of Cocaine Dependence [Phase 2]
Phase 2 trial results for vigabatrin in cocaine dependence have been posted.
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CLINICAL_TRIALS trial_result · 2012-05-10Clinical Trial Update: First in Humans Study of JDTic [Phase 1]
First-in-human Phase 1 study of JDTic for cocaine dependence was terminated.
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CLINICAL_TRIALS trial_result · 2012-04-09Clinical Trial Update: Efficacy of Varenicline in Methadone-Stabilized Cocaine Users [NA]
Clinical trial update on the efficacy of varenicline in methadone-stabilized cocaine users; results posted after completion.
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CLINICAL_TRIALS trial_result · 2012-03-30Clinical Trial Update: Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2 [NA]
This completed clinical trial from UConn Health evaluated voucher-based incentives versus prize-based incentives for cocaine-dependent patie…