Cocaine Dependence
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CLINICAL_TRIALS trial_result · 2019-08-26Clinical Trial Update: A Pilot Study of Candesartan as a Treatment for Cocaine Dependence [Phase 2]
Phase 2 pilot study investigating candesartan for cocaine dependence has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-22Clinical Trial Update: The Efficacy of Doxazosin for Cocaine Users [Phase 1]
Phase 1 clinical trial update evaluating the efficacy of doxazosin for cocaine dependence has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-06Clinical Trial Update: A Phase II Trial of Varenicline for the Treatment of Cocaine Dependence [Phase 2]
Phase II trial evaluating varenicline for cocaine dependence has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-22Clinical Trial Update: Pharmacogenetics of Doxazosin for Cocaine Dependence [Phase 2]
Phase 2 clinical trial update on pharmacogenetics of doxazosin for cocaine dependence completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-17Clinical Trial Update: Impact of a Non-Drug Choice on Cocaine Reinforcement [EARLY_Phase 1]
Early-phase 1 clinical trial update examining the impact of a non-drug choice on cocaine reinforcement with completed status and posted resu…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1 [Phase 2, Phase 3]
A completed clinical trial investigating treatment of adult ADHD in methadone-maintained patients across Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1 [Phase 2]
A Phase 2 trial investigated modafinil combined with cognitive behavioral therapy for cocaine dependence; results completed and posted.
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CLINICAL_TRIALS trial_result · 2019-03-13Clinical Trial Update: Oxytocin in Cocaine Dependence [NA]
Clinical trial update for oxytocin in cocaine dependence shows completed status with posted results.
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1 [Phase 2]
Phase 2 trial assessing the effectiveness of N-acetylcysteine (NAC) in treating cocaine dependence has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-12Clinical Trial Update: Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence [Phase 2, Phase 3]
A multicenter trial investigated a combined pharmacotherapy for cocaine dependence across Phase 2 and Phase 3; results have been posted afte…
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CLINICAL_TRIALS trial_result · 2018-09-14Clinical Trial Update: The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence [Phase 1, Phase 2]
Clinical trial update on brief potent glutamatergic modulation for cocaine dependence; phases 1 and 2 terminated with posted results in 2018…
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CLINICAL_TRIALS trial_result · 2018-08-24Clinical Trial Update: Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patients [Phase 2, Phase 3]
Phase 2/3 clinical trial investigating the effects of mifepristone on stress sensitivity and relapse prevention in cocaine-dependent patient…
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers [Phase 1, Phase 2]
Clinical trial update on SYN117 for cocaine dependence, spanning Phase 1 and Phase 2, with completed status.
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence [Phase 1, Phase 2]
Open-label pilot study of lisdexamfetamine for cocaine dependence completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Brain Glutamate Receptors and Cocaine Dependence
Clinical trial investigating brain glutamate receptors for cocaine dependence has been terminated. The study was sponsored by the National I…
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Gender Differences in Response to Cues in Cocaine Dependence
This clinical trial update reports on gender differences in response to cues among individuals with cocaine dependence.
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Ovarian Hormones and Stress Induced Drug Craving [NA]
A completed clinical trial investigating the role of ovarian hormones in stress-induced drug craving in individuals with cocaine dependence.
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CLINICAL_TRIALS trial_result · 2018-04-12Clinical Trial Update: Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse [Phase 2]
Phase 2 clinical trial assessing whether striatal effective connectivity can predict treatment response in cocaine dependence; the study has…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Cognitive Remediation for Cocaine Dependence [Phase 2]
A Phase 2 clinical trial evaluating cognitive remediation for cocaine dependence has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence [Phase 2]
Phase 2 trial evaluating carbidopa/levodopa in combination with behavioral therapy for cocaine dependence has completed. Results have been p…
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CLINICAL_TRIALS trial_result · 2018-01-24Clinical Trial Update: Citicoline for Bipolar 1 Disorder and Cocaine Dependence [Phase 4]
Phase 4 trial investigating citicoline for Bipolar 1 Disorder and cocaine dependence; study completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-09Clinical Trial Update: Modafinil for Smoked Cocaine Self-Administration [Phase 2]
Phase 2 clinical trial investigating modafinil for reducing smoked cocaine self-administration in cocaine dependence; completed with posted …
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: Brain Function and Structure in Cocaine Dependence [Phase 2]
Phase 2 clinical trial on brain function and structure in cocaine dependence completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Therapeutic Cocaine Vaccine: Human Laboratory Study [Phase 2]
Phase 2 human laboratory study of a therapeutic cocaine vaccine for cocaine dependence; results have been posted after completion.
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2 [NA]
This completed clinical trial from Johns Hopkins University tested employment-based reinforcement to promote drug abstinence. Participants h…