Clostridioides Difficile Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Clostridium Difficile Vaccine Safety, Tolerability, and Immunogenicity Study in Japanese Adults [Phase 1]
Phase 1 trial evaluating safety, tolerability, and immunogenicity of a Clostridioides difficile vaccine in Japanese adults has completed.
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CLINICAL_TRIALS research · 2018-07-13Clinical Trial Update: Relationship Between C. Difficile Toxins' Serum Level With C. Difficile Infection
An ongoing study evaluating how serum levels of C. difficile toxins relate to C. difficile infection.
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea [Phase 3]
Phase 3 trial comparing cadazolid to vancomycin for Clostridioides difficile infection has completed and posted results, including safety da…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of cadazolid versus vancomycin for Clostridioides difficile infection has completed and r…
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FDA approval · 2018-04-03FDA Approved: FLAGYL — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
The FDA approved a supplemental application for Flagyl (metronidazole) from Pfizer Laboratories Div Pfizer Inc, resulting in changes to the …
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CLINICAL_TRIALS research · 2018-03-15Clinical Trial Update: Incidence and Economic Burden of Clostridium Difficile Infections (CDI) in the German Health Care System (IBIS)
This clinical trial update analyzes how often Clostridioides difficile infection occurs in Germany and the associated economic burden within…
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FDA approval · 2018-01-26FDA Approved: VANCOMYCIN HYDROCHLORIDE FOR ORAL SOLUTION — Original Application (Wilshire Pharmaceuticals, Inc.)
The FDA approved Wilshire Pharmaceuticals' vancomycin hydrochloride for oral solution under an original NDA for the treatment of Clostridioi…
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CLINICAL_TRIALS trial_result · 2017-12-27Clinical Trial Update: Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk Antibiotics [Phase 4]
Phase 4 trial evaluating oral vancomycin for primary prophylaxis of Clostridioides difficile infection in patients on high-risk antibiotics;…
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain [NA]
Clinical trial update evaluating whether the probiotic Lactobacillus plantarum 299v can prevent Clostridioides difficile infection, sponsore…
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CLINICAL_TRIALS withdrawal · 2017-11-27Clinical Trial Update: EGESTA - Emergent GI Therapy for Severe, Complicated CDI Using Fecal Microbiota Transplant [NA]
The NCT02968511 trial EGESTA evaluating emergent GI therapy for severe, complicated Clostridioides difficile infection using fecal microbiot…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: A Study of Ridinilazole (SMT19969) Compared With Fidaxomicin for the Treatment of Clostridium Difficile Infection (CDI) [Phase 2]
Phase 2 trial comparing Ridinilazole to Fidaxomicin for treating Clostridioides difficile infection has completed.
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Description of the Use of fidAxomicin in Hospitalized Patients With Documented Clostridium diFficile iNfection and of the managEment of These Patients
A completed clinical trial describes the use and management of fidaxomicin in hospitalized patients with Clostridioides difficile infection.
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CLINICAL_TRIALS trial_result · 2017-08-23Clinical Trial Update: A Multi-Site Clinical Evaluation of the ARIES Clostridium Difficile Assay in Symptomatic Patients
A multi-site clinical evaluation of the ARIES Clostridioides difficile assay in symptomatic patients has completed, with results reported fr…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Predictive Value of the Immune Response of the Host in Clostridium Difficile Infections [NA]
This clinical trial update reports on the predictive value of the host immune response in patients with Clostridioides difficile infection. …
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Oral Vaccination Against Clostridium Difficile Infection [Phase 1]
Phase 1 clinical trial of an oral vaccine against Clostridioides difficile infection was terminated.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin [Phase 4]
Phase 4 trial comparing fidaxomicin versus vancomycin for Clostridioides difficile infection has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD) [Phase 2]
Phase 2 clinical trial evaluating efficacy, safety and tolerability of cadazolid for Clostridioides difficile infection has been completed.
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Dose-Confirmation, Immunogenicity and Safety Study of the Clostridium Difficile Vaccine Candidate VLA84 in Healthy Adults Aged 50 Years and Older. Phase II Study [Phase 2]
A Phase II dose-confirmation study of the Clostridioides difficile vaccine candidate VLA84 in adults 50 and older evaluated immunogenicity a…
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CLINICAL_TRIALS withdrawal · 2017-05-10Clinical Trial Update: Addition of Lactobacillus to Metronidazole in Treatment of CDAD [Phase 4]
A Phase 4 trial evaluating addition of a Lactobacillus probiotic to metronidazole for Clostridioides difficile infection has been withdrawn.
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CLINICAL_TRIALS research · 2017-05-04Clinical Trial Update: MicroTrans - A Multicenter Registry of Fecal Microbiota Transplantation
Clinical trial update describing MicroTrans, a multicenter registry evaluating fecal microbiota transplantation for Clostridioides difficile…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Host Immune Response to Clostridium Difficile Infection in Inflammatory Bowel Disease Patients
A clinical trial update describing how the host immune system responds to Clostridioides difficile infection in patients with inflammatory b…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Treatment of Initial Clostridium Difficile Infection [NA]
This clinical trial update notes the completion of a study on treatment of initial Clostridioides difficile infection (NCT03107169) conducte…
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CLINICAL_TRIALS research · 2017-03-30Clinical Trial Update: A Novel Faecal Microbiota Transplantation System for Treatment of Primary and Recurrent Clostridium Difficile Infection [NA]
This entry provides an update on a clinical trial evaluating a novel fecal microbiota transplantation system for treating primary and recurr…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Intracolonic Vancomycin Therapy in Severe C. Diff Colitis [NA]
A terminated clinical trial studied intracolonic vancomycin for severe Clostridioides difficile colitis; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy [NA]
Clinical trial evaluating antibiotic prophylaxis for urinary catheter removal after radical prostatectomy; the study was terminated and resu…