Cleft Lip
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)
Clinical trial update for the ACCQUIREnet network focusing on cleft lip and/or cleft palate research; enrollment is by invitation.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Pilot Study of Smartphone -Based AI Assisted Ultrasound Guided Infraorbital Nerve Block in Pediatric Cleft Lip Repair [NA]
This entry reports a pilot study evaluating smartphone-based AI-assisted ultrasound-guided infraorbital nerve block for pediatric cleft lip …
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery
A clinical trial evaluating perioperative analgesia in neonates undergoing primary cleft lip repair has completed.
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CLINICAL_TRIALS other · 2025-04-25Clinical Trial Update: Effects of AlignBabyCleft (ABaCleft) [NA]
This clinical trial update describes AlignBabyCleft (ABaCleft) for cleft lip and cleft palate, which is not yet recruiting.
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CLINICAL_TRIALS other · 2025-03-20Clinical Trial Update: Evaluation of a Novel Nasal Conformer in Pediatric Patients [Phase 2]
Phase 2 clinical trial evaluating a novel nasal conformer in pediatric patients undergoing nasal procedures for cleft lip; the study is not …
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Evaluation of a HA Dermal Filler in the Treatment of Lip Deformity [NA]
Clinical trial evaluating a hyaluronic acid dermal filler for lip deformity due to cleft lip or lip scar is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: Comparison Between Low Level Laser Therapy and Active Oxygen Releasing Gel on Wound Healing Cleft Lip Patients [Phase 1]
Phase 1 clinical trial comparing Low Level Laser Therapy and Active Oxygen Releasing Gel for wound healing in cleft lip patients has complet…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Prosthetic Rehabilitation of Lip and Palate Deformaties in Neonates Using Two Different Approaches [NA]
Clinical trial comparing two prosthetic approaches for neonatal lip and palate deformities; the study has completed.
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Effect of Collagen Matrix Graft on Palatal Fistula Formation After Cleft Palate Repair [NA]
This update reports on a completed clinical trial evaluating the effect of a collagen matrix graft on palatal fistula formation after cleft …
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Targeting Surgeons' Decision-Making for Cleft Lip Surgery [NA]
A Tufts University-sponsored clinical trial on surgeons' decision-making for cleft lip surgery is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: Indications and Evaluation of Microfat Grafting in Cleft Lip Nasal Deformities [NA]
Clinical trial update describing a study at Assiut University evaluating microfat grafting for cleft lip and nasal deformities, with recruit…
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance [NA]
Clinical trial evaluating nasal stent designs with a Nasoalveolar Molding appliance for cleft lip and cleft lip/palate; currently not recrui…
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating botulinum toxin to improve cosmetic outcomes after primary cleft lip repair has completed, with result…
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Dexmedetomidine as Adjuvant for Bupivacaine in Ultrasound Guided Infraorbital Nerve Block for Cleft Lip Repair [Phase 4]
Phase 4 trial evaluating dexmedetomidine as an adjuvant to bupivacaine for ultrasound-guided infraorbital nerve block in cleft lip repair ha…
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CLINICAL_TRIALS research · 2018-05-04Clinical Trial Update: FaceBase Biorepository
The FaceBase Biorepository study (NCT01252264), sponsored by Jeff Murray, focusing on craniofacial abnormalities including cleft lip and cle…
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: Silicone Gel in the Treatment of Cleft Lip Scars [Phase 3]
A Phase 3 trial evaluating silicone gel for treating cleft lip scars has completed.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Oral Cleft Prevention Program [Phase 3]
Phase 3 clinical trial update for the Oral Cleft Prevention Program conducted by the University of Iowa shows the study has completed enroll…
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery. [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluated infra-orbital nerve block for postoperative analgesia in children undergoing cleft lip surgery. The stu…
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CLINICAL_TRIALS trial_result · 2016-12-02Clinical Trial Update: Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients [NA]
An update noting the completion of a clinical trial evaluating two primary surgical protocols for facial growth in patients with unilateral …
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CLINICAL_TRIALS research · 2015-07-22Clinical Trial Update: Biochemical and Histological Comparison of Nasal and Auricular Cartilage in the Fetus and Newborn With Cleft Lip Carrier [NA]
Clinical trial update comparing biochemical and histological features of nasal versus auricular cartilage in fetuses and newborns with cleft…
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic Treatment [NA]
This clinical trial update compares alveolar bone grafting outcomes in cleft lip patients who did and did not receive orthodontic treatment.
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CLINICAL_TRIALS trial_result · 2015-03-27Clinical Trial Update: TWIST Human Gene and Cleft Lips and Palates [NA]
The TWIST gene trial for cleft lip/palate has been terminated; no results are reported.
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: Articulation and Phonology in Children With Unilateral Cleft Lip and Palate
The clinical trial investigating articulation and phonology in children with unilateral cleft lip and palate has completed.
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: Oral Cleft Prevention Trial in Brazil [Phase 3]
Phase 3 oral cleft prevention trial in Brazil, sponsored by NICHD Global Network for Women's and Children's Health, has completed. It target…
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: Systematic Pediatric Care for Oral Clefts - South America [NA]
This clinical trial update reports that the NICHD Global Network study on systematic pediatric care for children with cleft lip and/or palat…