Cirrhosis
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease [NA]
A clinical trial update describes testing LiverWatch, a home-based remote-monitoring intervention for advanced liver disease, which is curre…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: HepHospital: A Pilot Trial of a Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease [NA]
A pilot clinical trial evaluating a Hepatology Home Hospital intervention for patients with advanced liver disease, including cirrhosis and …
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Mechanisms of Perioperative Systemic Inflammation in the Development of PND in Cirrhotic Patients
A clinical trial from Sichuan Provincial People's Hospital investigates how perioperative systemic inflammation may contribute to postoperat…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Prognostic Model for MASLD Related Cirrhosis
Clinical trial update describing a prognostic model for MASLD-related cirrhosis; the study status is not yet recruiting.
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Role of Early API in Accurately Differentiating Hepatocellular Carcinoma From Dysplastic Nodules in Cirrhotic Patients
This clinical trial update discusses the role of an early API to differentiate hepatocellular carcinoma from dysplastic nodules in patients …
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients [NA]
A pilot trial evaluating the feasibility of using home blood pressure monitoring to optimize midodrine dosing in patients with decompensated…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Lung Point of Care Ultrasound to Guide Albumin Administration in Cirrhosis [Phase 3]
A Phase 3 trial evaluating whether point-of-care lung ultrasound can guide albumin administration in cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Patient Buddy App for the Prevention of Avoidable Readmission in Cirrhosis
This clinical trial update reports the completion and posting of results for a study evaluating the Patient Buddy App to prevent avoidable r…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease [NA]
LiverPAL is evaluating inpatient palliative care for patients with advanced liver disease, and the trial status is recruiting.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Danazol for Treatment of Cytopenias in Patients With Cirrhosis [Phase 2]
A Phase 2 clinical trial evaluating danazol for cytopenias in patients with cirrhosis is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Impact of Nutritional Management on the Frailty of Patients Waiting for Liver Transplantation (Via the LFI Tool) [NA]
This clinical trial update indicates that a study evaluating nutritional management using the LFI tool to address frailty in patients with c…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Comparison of Blood Products Required Using Two Different ROTEM Cut-offs Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure (ACLF) Patients With Severe Coagulopathy [NA]
A clinical trial update describing ongoing recruitment for a study comparing two ROTEM-based thresholds for transfusing blood products befor…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer [Phase 1, Phase 2]
Clinical trial update for Zanzalintinib in second-line and beyond for advanced hepatocellular carcinoma, covering Phase 1 and Phase 2, with …
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Non-invasive Assessment for Outcome Prediction in Patients With Hepatocellular Carcinoma
A clinical trial led by The Chinese University of Hong Kong is currently recruiting to evaluate non-invasive methods for predicting outcomes…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Natural History of Advanced Chronic Liver Diseases
Clinical trial NCT07042308 in Hong Kong is currently recruiting to study the natural history of advanced chronic liver diseases, including c…
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: Allopurinol and Pathogenesis of Cirrhosis [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating allopurinol for the pathogenesis of cirrhosis has completed. The study was sponsored by Tanta Un…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Study of microRNAs in a Decompensated Cirrhosis
A clinical trial titled 'Study of microRNAs in a Decompensated Cirrhosis' is currently recruiting in France. The study aims to investigate m…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434 [Phase 1]
A Phase 1 clinical trial assessing how hepatic impairment, including cirrhosis, influences the pharmacokinetics and safety of VIR-2218 and V…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES) [Phase 3]
This is a Phase 3 clinical trial update indicating the MAESTRO-NASH-OUTCOMES study of resmetirom in patients with well-compensated NASH cirr…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial [Phase 3]
Phase 3 multicenter double-blind trial assessing long-term carvedilol to prevent hepatic decompensation or death in asymptomatic Child-Pugh …
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury [Phase 2]
A Phase 2 clinical trial is investigating droxidopa to increase mean arterial pressure in patients with decompensated cirrhosis and acute ki…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Endosonographic Shear Wave Elastography to Assess Liver and Splenic Fibrosis
This clinical trial is evaluating endosonographic shear wave elastography as a method to assess liver and splenic fibrosis and is currently …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Application of Bacterial DNA Quantitative Detection in Diagnosis of SBP in Cirrhosis: A Multi Center Diagnostic Experiment
A multicenter diagnostic trial evaluating quantitative bacterial DNA detection for diagnosing spontaneous bacterial peritonitis in patients …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients [NA]
This clinical trial assesses whether laparoscopic splenectomy affects liver reserve function in patients with cirrhosis, and it is currently…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: FMT in Cirrhosis and Hepatic Encephalopathy [Phase 1, Phase 2]
This update reports the completed Phase 1 and Phase 2 trials of fecal microbiota transplantation for cirrhosis and hepatic encephalopathy, w…