Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Tolvaptan for Ascites in Cirrhotic Patients [Phase 4]
A Phase 4 clinical trial evaluating tolvaptan for ascites in cirrhotic patients has completed, with results posted in July 2015.
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Terlipressin in Cirrhotic Patients With Recidivation Ascites Treated With Paracentesis and Albumin [Phase 3]
Phase 3 clinical trial update shows terlipressin in cirrhotic patients with recurrent ascites treated with paracentesis and albumin has comp…
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Sensitivity of Alternative NRL972 Detection Methods in Healthy Subjects [Phase 1]
Phase 1 trial update from Norgine evaluating the sensitivity of alternative detection methods for the compound NRL972 in healthy subjects; t…
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: Vitamin D Supplementation in Cirrhotic Patients [Phase 2]
A Phase 2 trial evaluating vitamin D supplementation in patients with cirrhosis and vitamin D deficiency has completed.
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment. [NA]
A completed clinical trial investigating brain imaging in patients with chronic liver disease and functional impairment due to cirrhosis and…
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CLINICAL_TRIALS research · 2015-05-29Clinical Trial Update: Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis [Phase 4]
A Phase 4 clinical trial evaluating empirical versus second-line antibiotic therapy for healthcare-associated infections in patients with ci…
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure
This clinical trial update characterizes infections in patients with cirrhosis and/or acute-on-chronic liver failure, detailing the spectrum…
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CLINICAL_TRIALS trial_result · 2015-05-25Clinical Trial Update: Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome
Completed clinical trial evaluating whether resting-state default mode network fMRI maps can predict outcomes in hepatic encephalopathy rela…
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CLINICAL_TRIALS withdrawal · 2015-05-12Clinical Trial Update: Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) [NA]
A clinical trial evaluating lactulose versus polyethylene glycol for hepatic encephalopathy has been withdrawn.
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FDA approval · 2015-04-26FDA Approved: SPIRONOLACTONE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for Spironolactone from Mylan Pharmaceuticals Inc., indicating an approved change to an already-appr…
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CLINICAL_TRIALS research · 2015-04-23Clinical Trial Update: Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment [NA]
Clinical trial update evaluating whether proteasome serves as a biomarker for hepatocellular carcinoma in cirrhotic patients after curative …
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CLINICAL_TRIALS research · 2015-04-21Clinical Trial Update: Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patients [Phase 2, Phase 3]
This document reports a Phase 2/3 clinical trial evaluating rifaximin in combination with propranolol versus propranolol alone in patients w…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: Effects of the Administration of Ornithine Phenylacetate in Patients With Cirrhosis and Upper Gastrointestinal Bleeding [Phase 2, Phase 3]
A phase 2/3 trial evaluating ornithine phenylacetate in patients with cirrhosis and upper gastrointestinal bleeding has completed.
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CLINICAL_TRIALS trial_result · 2015-03-19Clinical Trial Update: Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding [Phase 3]
A Phase 3 clinical trial evaluates whether adding a statin to standard therapy reduces recurrent hemorrhage in patients with cirrhosis and p…
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Single Pass Albumin Dialysis in Patients With Cirrhosis [Phase 1, Phase 2]
Clinical trial update indicating completion of Phase 1 and Phase 2 studies of Single Pass Albumin Dialysis in patients with cirrhosis and re…
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding. [Phase 3]
Phase 3 trial comparing self-expandable esophageal stents to balloon tamponade for refractory esophageal variceal bleeding has completed.
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Safety and Efficacy of Baclofen for Treatment of Muscle Spasms in Patients With Cirrhosis: A Pilot Study [Phase 2]
Phase 2 pilot trial evaluating baclofen for treating muscle spasms in patients with cirrhosis; the study was completed and results were post…
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. [NA]
A completed clinical trial comparing GoLYTELY (polyethylene glycol 3350-electrolyte solution) with lactulose in hepatic encephalopathy, with…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Insertion Technique in Large Volume Paracentesis [NA]
This clinical trial update reports the completion of a study investigating insertion technique for large-volume paracentesis in patients wit…
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Phase Angle and Mortality in Patients With Cirrhosis
A completed clinical study examining the relationship between phase angle and mortality in patients with cirrhosis and malnutrition.
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CLINICAL_TRIALS trial_result · 2014-11-18Clinical Trial Update: Bioelectrical Impedance Vector Analysis in Cirrhotic Patients
A completed clinical trial evaluating Bioelectrical Impedance Vector Analysis in patients with cirrhosis and hepatic encephalopathy.
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CLINICAL_TRIALS research · 2014-10-15Clinical Trial Update: Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing daptomycin plus meropenem versus ceftazidime for nosocomial spontaneous bacterial peritonitis in cirrho…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Terlipressin Given As I.V. Boluses Versus Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome [Phase 2, Phase 3]
The document reports a Phase 2/3 clinical trial comparing intravenous bolus administration of terlipressin to continuous intravenous infusio…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome [Phase 2, Phase 3]
A Phase 2/Phase 3 randomized trial comparing terlipressin plus albumin to midodrine plus octreotide for hepatorenal syndrome in cirrhosis ha…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices [NA]
This clinical trial update investigates predictive factors and outcomes of esophageal ulcers after endoscopic treatment of esophageal varice…