Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-04-08Clinical Trial Update: Study to Investigate Tolerability and Efficacy of MK5172 / MK8742 Without Ribavirin for 12 Weeks in Patients With Chronic HCV G1b Infection With Compensated Cirrhosis [Phase 3]
Phase 3 study assessing tolerability and efficacy of a ribavirin-free regimen of grazoprevir and elbasvir for 12 weeks in patients with chro…
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CLINICAL_TRIALS withdrawal · 2016-03-11Clinical Trial Update: Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy
A clinical trial evaluating the effect of music on attention and prospective memory in hepatic encephalopathy and cirrhosis has been withdra…
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CLINICAL_TRIALS withdrawal · 2016-03-10Clinical Trial Update: The Use of Transient Elastography to Predict Clinical Decompensation in Patients With Early Cirrhosis
A clinical trial evaluating whether transient elastography can predict clinical decompensation in patients with early cirrhosis was withdraw…
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FDA approval · 2016-03-08FDA Approved: FUROSEMIDE — Supplemental Application (Phlow Corporation)
FDA approved a supplemental application for furosemide submitted by Phlow Corporation.
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Ledipasvir/Sofosbuvir Fixed-Dose Combination and Vedroprevir With or Without Ribavirin in Treatment-Experienced Participants With Chronic Genotype 1 HCV Infection and Cirrhosis [Phase 2]
Phase 2 trial evaluating fixed-dose Ledipasvir/Sofosbuvir with or without Vedroprevir (with or without ribavirin) in treatment-experienced c…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation [Phase 2]
Phase 2 trial evaluating sofosbuvir and ribavirin in adults with chronic hepatitis C and cirrhosis, including patients with portal hypertens…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Sugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver Resection [Phase 4]
Phase 4 trial comparing sugammadex with neostigmine in patients with cirrhosis undergoing liver resection has completed.
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension [Phase 2]
Phase 2 exploratory haemodynamic study in patients with compensated cirrhosis and portal hypertension. Results were posted in January 2016.
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CLINICAL_TRIALS withdrawal · 2016-01-15Clinical Trial Update: Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side Effects [Phase 2]
A Phase 2 trial comparing eplerenone with spironolactone for ascites due to liver cirrhosis has been withdrawn from further study.
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CLINICAL_TRIALS trial_result · 2015-12-30Clinical Trial Update: Comparison And Outcomes Of Fluid Resucitation With 0.9% Normal Saline And 5% Albumin In Cirrhosis Patients With Sepsis Induced Hypotension [NA]
Completed trial comparing 0.9% normal saline versus 5% albumin for fluid resuscitation in cirrhosis with septic shock, reporting outcomes.
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: The Effect of Hepatic Vein Pressure Gradient(HVPG)-Guided Therapy in Cirrhotic Patients With Esophagogastric Varices [Phase 4]
Clinical trial update on HVPG-guided therapy for cirrhotic patients with esophagogastric varices (Phase 4); status is currently unknown.
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Mechanisms Involved in the Benefits of an Exercise Programme in Patients With Cirrhosis [NA]
A completed clinical trial investigating the mechanisms behind the benefits of an exercise program in patients with cirrhosis. The study aim…
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CLINICAL_TRIALS research · 2015-11-24Clinical Trial Update: Radiofrequency-assisted Hepatectomy on the Outcomes of HCC Patients With Cirrhosis [NA]
This document is a clinical trial registry entry for a study evaluating radiofrequency-assisted hepatectomy in hepatocellular carcinoma pati…
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making [NA]
This completed clinical trial evaluated a culturally sensitive, values-guided decision aid to help patients with serious illnesses make end-…
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: Sarcopenia and Cirrhosis [NA]
This clinical trial update indicates that the study evaluating sarcopenia in patients with cirrhosis (NCT02132962) has completed, sponsored …
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CLINICAL_TRIALS trial_result · 2015-10-27Clinical Trial Update: Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients
This clinical trial update describes the investigation of the Transjugular Intrahepatic Portosystemic Shunt (TIPS) and its effect on gut mic…
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CLINICAL_TRIALS trial_result · 2015-10-22Clinical Trial Update: Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate [Phase 4]
Phase 4 clinical trial evaluating L-ornithine L-aspartate for hepatic encephalopathy has completed. The update covers results from patients …
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Effect of Physical Training Program on Health-related Quality of Life in Cirrhosis [Phase 2]
Phase 2 clinical trial evaluating a physical training program for improving health-related quality of life in patients with cirrhosis has co…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis [Phase 4]
This update notes the completion of a Phase 4 clinical trial evaluating taurine's effects on portal hemodynamics in patients with advanced l…
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CLINICAL_TRIALS trial_result · 2015-09-16Clinical Trial Update: Evaluation of the Strip PeriScreen for the Fast Diagnosis of the Spontaneous Infection of the Liquid of Ascites During the Cirrhosis [NA]
A completed clinical trial evaluating the Strip PeriScreen diagnostic strip for rapid detection of spontaneous infection in ascitic fluid fr…
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Comparison of Covered and Bare Stent in TIPS [NA]
This document reports the completion of a clinical trial comparing covered versus bare stents in transjugular intrahepatic portosystemic shu…
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CLINICAL_TRIALS trial_result · 2015-08-21Clinical Trial Update: Study of the Benefit of Exercise and Aminoacid Supplements in Cirrhotic Patients [NA]
A completed clinical trial evaluating the benefits of exercise and amino acid supplements in patients with cirrhosis.
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CLINICAL_TRIALS research · 2015-08-13Clinical Trial Update: Incidence and Spectrum of Acute Kidney Injury in Cirrhotics and Assessment of New Biomarkers as Early Predictors of Acute Kidney Injury
This completed clinical study investigates how often acute kidney injury occurs in patients with cirrhosis and assesses new biomarkers for e…
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CLINICAL_TRIALS withdrawal · 2015-08-04Clinical Trial Update: The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis
A study investigating the impact of large-volume paracentesis on fatigue, sleep, and quality of life in cirrhosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-07-28Clinical Trial Update: Efficacy and Safety of Tolvaptan in Cirrhotic Patients With Hyponatremia
This clinical trial update reports on the efficacy and safety of tolvaptan in cirrhotic patients with hyponatremia, with the trial status co…