Cirrhosis of the Liver
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Efficacy and Safety of Rivaroxaban in the Management of Acute Non-neoplastic PVT Compensated Cirrhosis [Phase 3]
Phase 3 clinical trial evaluating rivaroxaban for efficacy and safety in acute non-neoplastic portal vein thrombosis in compensated cirrhosi…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: A Randomized, Open-Label Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir Co-administered With Ribavirin (RBV) in Adults With Genotype 4 Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis (AGATE-1) [Phase 3]
Phase 3 AGATE-1 evaluated the safety and efficacy of Ombitasvir/Paritaprevir/Ritonavir with Ribavirin in adults with genotype 4 chronic hepa…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Dextran, a Plasma Expander, Offers New Hope for Patients With Decompensated Liver Cirrhosis and Acute Kidney Injury [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluating Dextran as a plasma expander for decompensated liver cirrhosis with acute kidney injury have completed…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Primary Prevention Hepatocellular Carcinoma by Metformin [Phase 3]
Phase 3 trial evaluating metformin for primary prevention of hepatocellular carcinoma in people with chronic liver disease, including chroni…
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CLINICAL_TRIALS trial_result · 2016-09-12Clinical Trial Update: THE IMMUNOLOGICAL EFFECTS AND METABOLIC TOLERANCE OF LIPID INFUSION IN PATIENTS WITH CIRRHOSIS. [NA]
A completed clinical trial evaluating the immunological effects and metabolic tolerance of lipid infusion in patients with cirrhosis, includ…
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: Effects of Treatment of Ascites by the ALFApump System on Renal and Circulatory Function [Phase 2]
Phase 2 clinical trial update on using the ALFApump System to treat ascites in cirrhosis and its effects on renal and circulatory function.
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Influence of Probiotics on Infections in Cirrhosis [NA]
Completed clinical trial evaluating the effect of probiotic therapy on infections in cirrhosis of the liver.
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Sofosbuvir/Simeprevir Plus a Flat Dose of Ribavirin in Genotype 1 Elderly HCV Cirrhotic Patients [Phase 4]
Phase 4 trial assessing sofosbuvir/simeprevir plus a flat dose of ribavirin in genotype 1 elderly patients with liver cirrhosis; the study i…
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CLINICAL_TRIALS trial_result · 2013-12-02Clinical Trial Update: Cardiopulmonary Exercise Testing in Cirrhotic Patients: a Pilot Study
A pilot study evaluating the use of cardiopulmonary exercise testing in patients with cirrhosis (end-stage liver disease) to assess function…
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CLINICAL_TRIALS trial_result · 2013-10-23Clinical Trial Update: A Phase II, Double-blinded, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Vitalliver in Patients With Decompensated Cirrhosis [Phase 2]
A Phase II double-blind, randomized trial evaluating Vitalliver in patients with decompensated cirrhosis has completed, assessing efficacy a…
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CLINICAL_TRIALS trial_result · 2011-11-18Clinical Trial Update: Efficacy and Safety Study on Nasogastric (NG) Tube in Patients With Upper Gastrointestinal Bleed [NA]
The trial evaluated the efficacy and safety of nasogastric tube use in patients with upper gastrointestinal hemorrhage, including those with…
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CLINICAL_TRIALS trial_result · 2011-04-25Clinical Trial Update: Evaluation of Cirrhosis and Malignant Hepatic Lesions Using Novel MR Contrast Agents
This entry reports a clinical trial evaluating novel MR contrast agents for assessing cirrhosis and malignant hepatic lesions, including hep…
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CLINICAL_TRIALS trial_result · 2011-04-18Clinical Trial Update: Pegylated Alfa-2b Interferon Therapy of Patients With Hepatitis C-related Cirrhosis and High Liver Cell Proliferation (P02733/MK-4031-085) [Phase 3]
This document provides a Phase 3 trial update on pegylated interferon alfa-2b in patients with hepatitis C-related cirrhosis and high liver …
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CLINICAL_TRIALS trial_result · 2009-03-06Clinical Trial Update: Clearance of NRL972 in Patients With Cirrhosis and in Healthy Volunteers [Phase 1]
Phase 1 trial update on NRL972 shows pharmacokinetic clearance in patients with cirrhosis and in healthy volunteers.
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CLINICAL_TRIALS trial_result · 2009-01-12Clinical Trial Update: Satavaptan Dose-Ranging Study in Hyponatraemic Patients With Cirrhotic Ascites [Phase 2]
Sanofi conducted a Phase 2 dose-ranging trial of satavaptan in hyponatraemic patients with cirrhotic ascites; the study status is completed.
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CLINICAL_TRIALS trial_result · 2006-07-11Clinical Trial Update: Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis [Phase 1]
A Phase 1 clinical trial of L-NMMA in patients with cirrhosis of the liver has completed.