Rhinosinusitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
This clinical trial update outlines a pilot study using electrobulbogram (EBG), fMRI, and diffusion-weighted imaging to explore central brai…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Propel Drug-Eluting Sinus Implant Family IBUKI Cohort
Medtronic reports a clinical trial update for the Propel Drug-Eluting Sinus Implant (IBUKI Family) cohort. The study is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating ivacaftor for acquired CFTR dysfunction in chronic rhinosinusitis, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis (EDSPD Protocol)
Clinical trial protocol evaluating ivacaftor for acquired CFTR dysfunction in chronic rhinosinusitis; the study is currently active but not …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Impact of Sinus Surgery on Individuals With Cystic Fibrosis
A UCLA-led clinical trial is investigating the impact of sinus surgery on individuals with cystic fibrosis and chronic rhinosinusitis and is…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Inflammatory Profiles, Histopathological Features, and Remodeling Factors in Chronic Rhinosinusitis With Nasal Polyps [NA]
This clinical trial explores inflammatory profiles, tissue histology, and remodeling factors in chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis
This clinical trial update describes the nasal potential difference (NPD) protocol being studied in chronic rhinosinusitis and notes that th…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult Patients [Phase 3]
Phase 3 trial evaluating Raphamin for acute rhinosinusitis in adults is currently recruiting, with no results reported yet.
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Validity of the French Version of the Child's Chronic Rhinosinusitis Questionnaire
The trial has completed and reports on the validity of the French version of the Child's Chronic Rhinosinusitis Questionnaire.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps [Phase 2]
A Phase 2 clinical trial is evaluating the long-term safety and efficacy of TQH2722 Injection for chronic rhinosinusitis with or without nas…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Microbiota Transfer for Chronic Rhinosinusitis [NA]
A clinical trial update describes a microbiota transfer study for chronic rhinosinusitis; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: The Efficacy of Olfactory Cleft Steroid Drops in Patients With CRS With Olfactory Cleft Obstruction [NA]
This ClinicalTrials.gov entry describes a study evaluating olfactory cleft steroid drops for chronic rhinosinusitis with olfactory dysfuncti…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: RhinAV_Evaluation of Treatments for Acute Viral Rhinitis, Rhinosinusitis, and Rhinopharyngitis [NA]
This clinical trial update outlines the RhinAV evaluation of treatments for acute viral rhinitis, rhinosinusitis, and rhinopharyngitis, whic…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Intra-Sinus Povidone-Iodine and Budesonide After Endoscopic Sinus Surgery for Chronic Rhinosinusitis [Phase 3]
Phase 3 clinical trial evaluating intra-sinus povidone-iodine followed by budesonide after endoscopic sinus surgery for chronic rhinosinusit…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: The Sinonasal Microbiome
This update describes an ongoing, non-recruiting clinical trial at the University of Chicago examining the sinonasal microbiome in sinonasal…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Functional Endoscopic Sinus Surgery Study [Phase 1, Phase 2]
A Functional Endoscopic Sinus Surgery study for Chronic Rhinosinusitis, spanning Phase 1 and Phase 2, is currently active but not recruiting…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Effect of Chinese Herbal Medicine Nasal Irrigation on the Postoperative Care of Chronic Rhinosinusitis [Phase 2]
A Phase 2 clinical trial is evaluating whether nasal irrigation with Chinese herbal medicine improves postoperative care for chronic rhinosi…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: The Role of IL5 in Epithelial Cell Integrity [EARLY_Phase 1]
An early-phase Phase 1 trial sponsored by Johns Hopkins University examines the role of IL-5 in epithelial cell integrity in chronic rhinosi…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures [NA]
A Cedars-Sinai-led clinical trial is evaluating lavender aromatherapy to reduce anxiety and pain during awake otolaryngology procedures and …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Treatment Decision-Making Among Patients With Chronic Rhinosinusitis [NA]
A clinical trial is currently enrolling by invitation to study treatment decision-making among patients with chronic rhinosinusitis.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF) [NA]
Clinical trial update on a bioresorbable nasal dressing containing mometasone furoate for chronic rhinosinusitis (with or without nasal poly…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy [Phase 3]
Phase 3 clinical trial update examining sinonasal therapies and histologic correlations in patients with cystic fibrosis and chronic rhinosi…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Paclitaxel-Coated Nasal Balloon for the Treatment of Recurrent Chronic Rhinosinusitis With or Without Nasal Polyps (FIH) [EARLY_Phase 1]
An early-phase, first-in-human study evaluating a paclitaxel-coated nasal balloon for recurrent chronic rhinosinusitis with or without nasal…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms [NA]
Clinical trial assessing the effectiveness of seawater nasal sprays on sinonasal symptoms; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Phase I Study Evaluating the Safety, Tolerability, and Pharmacokinetics of VVN432 Nasal Spray [Phase 1]
A Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of VVN432 nasal spray in chronic rhinosinusitis is currently recru…