Chronic Myeloid Leukemia
📧 Sign up to get email alerts when something new happens for Chronic Myeloid Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia [Phase 1]
This Clinical Trial Update reports on a Phase 1 study evaluating the combination of panobinostat (LBH589) and imatinib mesylate in patients …
-
FDA approval · 2014-07-30FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA granted approval of a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, Inc.
-
FDA approval · 2014-07-24FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) submitted by Takeda Pharmaceuticals America, Inc.
-
CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: Study Safety and Preliminary Efficacy of DCC-2036 in Patients With Leukemias (Ph+ CML With T315I Mutation) [Phase 1]
This update reports safety data and preliminary efficacy signals from a Phase 1 study of DCC-2036 in patients with Philadelphia chromosome–p…
-
CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Pharmacogenomics Validation for Imatinib in Chronic Myeloid Leukemia
This completed study provides pharmacogenomic validation for response to imatinib in patients with chronic myeloid leukemia.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers [Phase 2]
Phase 2 clinical trial update evaluating peptide vaccinations in patients with low-risk myeloid cancers, including myelodysplastic syndrome …
-
CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy [Phase 2]
Phase 2 trial of WT1 peptide vaccine in high-risk hematologic malignancies (myelodysplastic syndrome, acute myeloid leukemia, and chronic my…
-
CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Low Dose IL-2, Hematopoietic Stem Cell Transplantation, IL2 for GVHD [Phase 2]
Phase 2 trial update evaluating low-dose interleukin-2 in patients undergoing allogeneic hematopoietic stem cell transplantation to address …
-
CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: TALL-104 and Gleevec in Chronic Myelogenous Leukemia Patients [Phase 2]
Phase 2 trial update of TALL-104 with Gleevec for chronic myeloid leukemia; the study was terminated and results were posted in 2014.
-
CLINICAL_TRIALS trial_result · 2014-06-30Clinical Trial Update: Open Label Study of Subcutaneous Homoharringtonine (Omacetaxine Mepesuccinate) in Patients With Advanced CML [Phase 2]
Open-label Phase 2 trial evaluating subcutaneous homoharringtonine (omacetaxine mepesuccinate) in patients with advanced chronic myeloid leu…
-
CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Comparative Bioequivalence Study in Adult Patients Suffering From Chronic Myeloid Leukemia & Gastrointestinal Stromal Tumor Under Fed Conditions [Phase 2, Phase 3]
This update reports the completion of a Phase 2/3 comparative bioequivalence study in adults with chronic myeloid leukemia and gastrointesti…
-
CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 study evaluating vorinostat with or without isotretinoin in pediatric patients with recurrent or refractory solid tumors, lymphoma, …
-
CLINICAL_TRIALS trial_result · 2014-06-04Clinical Trial Update: Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive Leukemias [Phase 2]
Phase 2 study results of bosutinib (SKI-606) in Japanese patients with Philadelphia chromosome-positive leukemias are reported, focusing on …
-
CLINICAL_TRIALS trial_result · 2014-06-03Clinical Trial Update: Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation [Phase 2]
Phase 2 trial update of homoharringtonine (Omacetaxine mepesuccinate) in chronic myeloid leukemia with the T315I BCR-ABL mutation; results p…
-
CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Dasatinib Combination Therapy With the Smoothened (SMO) Inhibitor BMS-833923 in Chronic Myeloid Leukemia (CML) [Phase 1, Phase 2]
A Phase 1/2 study evaluated dasatinib in combination with the SMO inhibitor BMS-833923 for chronic myeloid leukemia and has completed with r…
-
CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Total-Body Irradiation With or Without Fludarabine Phosphate Followed By Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer [Phase 3]
Phase 3 trial evaluating total-body irradiation with or without fludarabine phosphate followed by donor stem cell transplant in hematologic …
-
CLINICAL_TRIALS trial_result · 2014-05-08Clinical Trial Update: Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood [Phase 1, Phase 2]
Phase 1/2 trial evaluating Wilms' Tumor 1 protein vaccine for blood cancers has completed. Results were posted on 2014-05-08.
-
CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 trial evaluating obatoclax mesylate in combination with vincristine, doxorubicin, and dexrazoxane in pediatric patients with relapse…
-
CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Natural Killer Index From Hematopoietic Stem Cell Graft [NA]
Clinical trial update on the natural killer index derived from hematopoietic stem cell graft. The study is listed as completed and includes …
-
CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia [Phase 1]
Phase 1 study of MK-2206 in pediatric patients with recurrent or refractory solid tumors or leukemias has completed.
-
CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: Bone Marrow Transplantation Plus Biological Therapy in Treating Patients With Chronic Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating bone marrow transplantation plus biological therapy for chronic myeloid leukemia; the study has completed.
-
CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib Mesylate [Phase 1]
A Phase 1 trial tested dasatinib with cyclosporine in chronic myeloid leukemia patients refractory or intolerant to imatinib. The study stat…
-
CLINICAL_TRIALS research · 2014-03-26Clinical Trial Update: Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single Vaccination [Phase 1, Phase 2]
Open-label Phase 1/2 clinical trial evaluating the safety and tolerability of donor-derived allogeneic B-cell concentrates to support immune…
-
CLINICAL_TRIALS trial_result · 2014-01-31Clinical Trial Update: STI571 in Treating Patients With Accelerated Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating STI571 (imatinib) in patients with accelerated-phase chronic myeloid leukemia has completed.
-
FDA approval · 2014-01-30FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) from Takeda Pharmaceuticals America, Inc.