Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: ACY-1215 in Combination With BCR Pathway Inhibitors in Relapsed CLL [Phase 1]
Phase 1 clinical trial update evaluating ACY-1215 (ricolinostat) in combination with B-cell receptor pathway inhibitors for relapsed chronic…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating an anti-pneumococcal vaccine strategy in patients with Chronic Lymphocytic Leukemia and Small lymphocyti…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation [Phase 2]
Phase 2 clinical trial evaluating glofitamab as monotherapy and in combination with polatuzumab vedotin, pirtobrutinib, or atezolizumab for …
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Safe Accelerated Venetoclax Escalation in CLL [Phase 1]
Phase 1 trial update reporting safe accelerated venetoclax escalation in chronic lymphocytic leukemia and small lymphocytic lymphoma.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Daratumumab and Ibrutinib in Treating Patients With Symptomatic Chronic Lymphocytic Leukemia [Phase 1]
This document provides an update on a Phase 1 clinical trial investigating the combination of daratumumab and ibrutinib to treat symptomatic…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL [Phase 2]
Phase 2 trial evaluating intermittent versus continuous venetoclax in combination with acalabrutinib for chronic lymphocytic leukemia and sm…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL) [Phase 2]
Phase 2 trial REVEAL evaluates retreatment with venetoclax plus acalabrutinib after a limited duration of venetoclax in patients with CLL/SL…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of Epcoritamab as a Consolidation Therapy in CLL/SLL [Phase 2]
Phase 2 study evaluating epcoritamab as consolidation therapy for chronic lymphocytic leukemia/small lymphocytic lymphoma is currently recru…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN) [Phase 1]
Phase 1 trial evaluating activated T cells expressing second- or third-generation CD19-directed CAR-T cells in advanced B-cell malignancies.…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: LEF1 EXPRESSION IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: A MARKER FOR DIAGNOSIS AND SURVIVAL PREDICTION
This clinical trial is currently recruiting to evaluate LEF1 expression in B-cell chronic lymphocytic leukemia and small lymphocytic lymphom…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Ibrutinib lead-in Followed by Venetoclax Plus Ibrutinib in Patients With RR CLL [Phase 2]
A Phase 2 trial evaluating an ibrutinib lead-in followed by venetoclax plus ibrutinib in relapsed/refractory chronic lymphocytic leukemia. T…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency [NA]
A Mayo Clinic-sponsored clinical trial evaluates cholecalciferol (vitamin D3) for improving survival in patients with newly diagnosed cancer…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma [Phase 1]
A Phase 1 trial is evaluating the combination of copanlisib and nivolumab in patients with Richter's transformation or transformed indolent …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia [Phase 2]
A phase 2 clinical trial evaluating the combination of acalabrutinib and obinutuzumab for Chronic Lymphocytic Leukemia and Small Lymphocytic…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL [Phase 1]
Clinical trial update for a Phase 1 study evaluating autologous peripheral blood lymphocytes in chronic lymphocytic leukemia and small lymph…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10) [Phase 2]
This clinical trial update notes that a Phase 2 study of DZD8586 in combination therapy for chronic lymphocytic leukemia and small lymphocyt…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial evaluating venetoclax in relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma is curren…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Acalabrutinib in Combination With Anti-CD20 and Venetoclax in Relapsed/Refractory or Untreated CLL/SLL/PLL [Phase 1]
Phase 1 trial evaluating acalabrutinib with anti-CD20 therapy and venetoclax in relapsed/refractory or untreated chronic lymphocytic leukemi…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating cytokine-treated veto cells as an adoptive therapy after stem cell transplantation for various hematolog…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers. [Phase 1, Phase 2]
BeiGene reports a Phase 1/2 trial evaluating the safety of novel dose ramp-up schedules for Sonrotoclax in chronic lymphocytic leukemia; the…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial evaluating acalabrutinib for chronic lymphocytic leukemia and small lymphocytic lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Precision Physical Exercise for Personalized Onco-Hematology. [NA]
An update on a clinical trial evaluating precision physical exercise for personalized management in onco-hematology, spanning hematologic ca…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL [Phase 2]
An update on a Phase II trial evaluating MOR00208 in combination with lenalidomide for relapsed/refractory or untreated older patients with …
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Extension Study of UC-961 (Cirmtuzumab) for Patients With Chronic Lymphocytic Leukemia Treated Previously With UC-961 [Phase 1]
This document reports an extension-phase study of UC-961 (cirmtuzumab) in patients with chronic lymphocytic leukemia; results have been post…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation [Phase 2]
A Phase 2 clinical trial is evaluating a triple therapy consisting of lisocabtagene maraleucel, nivolumab, and ibrutinib for Richter transfo…