Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax [Phase 1, Phase 2]
A Phase 1/2 trial evaluating pirtobrutinib (LOXO-305) as consolidation to eradicate minimal residual disease in chronic lymphocytic leukemia…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Mosunetuzumab for CLL MRD Clearance [Phase 1, Phase 2]
Clinical trial update for mosunetuzumab in chronic lymphocytic leukemia focusing on measurable residual disease clearance in Phase 1/2 studi…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma [Phase 1]
An ongoing Phase 1 clinical trial update for AS-1763 in adults with previously treated B-cell malignancies, including chronic lymphocytic le…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: ALICIA (Acalabrutinib in CLL Therapy)
Clinical trial update for the ALICIA study evaluating acalabrutinib in chronic lymphocytic leukemia; the study status is active but not recr…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
An ongoing clinical trial investigating muscle dysfunction in patients with hematologic diseases referred for stem cell transplantation.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Study of the Use of Venetoclax in Participants With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting
A real-world study evaluating venetoclax in patients with chronic lymphocytic leukemia is currently recruiting.
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CLINICAL_TRIALS other · 2025-12-08Clinical Trial Update: Registry of the German CLL Study Group
Ongoing registry study by the German CLL Study Group recruiting participants for trials involving chronic lymphocytic leukemia, small lympho…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Phase 1 Study of ZE50-0134 in Relapsed and Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Select Low-grad Lymphomas [Phase 1]
Phase 1 clinical trial update for ZE50-0134 in relapsed and refractory chronic lymphocytic leukemia, small lymphocytic lymphoma, and select …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Zanubrutinib and Venetoclax in CLL (ZANU-VEN) [Phase 2]
A Phase 2 clinical trial (ZANU-VEN) evaluating the combination of zanubrutinib and venetoclax for chronic lymphocytic leukemia and small lym…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: A Study of the Safety and Efficacy of Venetoclax for Participants With Chronic Lymphocytic Leukemia (CLL) Used in Routine Clinical Practice
This completed clinical trial evaluates the safety and effectiveness of Venetoclax for patients with chronic lymphocytic leukemia in routine…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Innovative Biomarkers of Cardiovascular Complications Associated With Second-generation Bruton Tyrosine Kinase Inhibitor Treatments: a Single-center Cohort Study
A single-center cohort study is assessing biomarkers of cardiovascular complications in patients treated with second-generation BTK inhibito…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: REfractorinesS to Ibrutinib BTKi and Systemic Targeted Therapy
This clinical trial update reports on refractoriness to ibrutinib, a Bruton Tyrosine Kinase inhibitor, and to systemic targeted therapies in…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: STop and Restart Acalabrutinib In fRail Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial of acalabrutinib for untreated chronic lymphocytic leukemia is ongoing. The study status is currently active but not recruit…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers [Phase 2]
A Phase 2 clinical trial evaluating nicotinamide in patients with chronic lymphocytic leukemia who have a history of non-melanoma skin cance…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: French Observational Study of Patients With Chronic Lymphocytic Leukemia Or Small Lymphocytic Lymphoma in Real-World Settings
A French observational study of patients with chronic lymphocytic leukemia or small lymphocytic lymphoma in real-world settings is ongoing b…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Multicenter, Single-Arm Exploratory Phase I Clinical Study (Assessment of Safety and Efficacy) of Fully Human BAFF-R Chimeric Antigen Receptor T-Cell Injection in Relapsed/Refractory BAFF-R-Positive B-Cell Lymphoma [Phase 1, Phase 2]
Clinical trial update describing a multicenter, single-arm Phase I/II exploratory study to assess the safety and efficacy of a fully human B…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Prospective Observational Trial to Assess Treatment Sequences and Factors That Impact Overall Sur-vival in Patients With Chronic Lymphocytic Leukaemia (CLL) Treated Within First-line Studies of the GCLLSG
A prospective observational trial by the German CLL Study Group to assess treatment sequences and factors that impact overall survival in pa…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients [Phase 3]
Acalabrutinib safety study in untreated and relapsed or refractory chronic lymphocytic leukemia patients (Phase 3) has completed.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Retention Rate of Acalabrutinib in a Non-interventional Setting
A non-interventional study update evaluating how long patients with chronic lymphocytic leukemia stay on acalabrutinib in real-world use.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: DZD8586 in Patients With Relapsed or Refractory CLL/SLL (TAI-SHAN8) [Phase 2]
A Phase 2 clinical trial evaluating DZD8586 in patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma …
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Evaluation of Risk-Adapted and MRD-Driven Strategy for Untreated Fit Patients With Intermediate Risk Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating a risk-adapted, MRD-driven strategy in untreated, fit patients with intermediate-risk chronic lymphocytic leukemia …
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Evaluation of the Safety and Efficacy of the Association of Ibrutinib and Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia With p53 Dysfunction [Phase 2]
Clinical trial evaluates the safety and efficacy of combining ibrutinib with daratumumab in relapsed/refractory chronic lymphocytic leukemia…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Phase II Trial GA101 Inbrutinib B CLL [Phase 2]
Phase II trial GA101 (obinutuzumab) in combination with ibrutinib for chronic lymphocytic leukemia has completed. The study was sponsored by…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma [Phase 1]
This clinical trial update describes a Phase 1 study of pevonedistat in combination with ibrutinib for relapsed or refractory chronic lympho…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Preemptive Therapy for High Risk Chronic Lymphoid Leukemia Stage A [Phase 2]
Phase 2 clinical trial update for preemptive therapy in high-risk chronic lymphocytic leukemia (Stage A); the study is currently active but …