Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2012-05-21Clinical Trial Update: Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells [Phase 1]
Phase 1 trial of autologous tumor cells engineered to express human IL-2 and CD40 ligand for chronic lymphocytic leukemia. The study has bee…
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CLINICAL_TRIALS trial_result · 2012-05-17Clinical Trial Update: Safety Study Of SNX-5422 To Treat Solid Tumor Cancers And Lymphomas [Phase 1]
A Phase 1 safety study of SNX-5422 for solid tumor malignancies and lymphoid cancers has been completed.
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CLINICAL_TRIALS trial_result · 2012-05-15Clinical Trial Update: Cladribine and Rituximab as Remission Induction Therapy Followed By Rituximab and Stem Cell Mobilization in Treating Patients With CLL [Phase 2]
A Phase 2 study assessing cladribine and rituximab as induction therapy, followed by rituximab and stem cell mobilization in patients with c…
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CLINICAL_TRIALS trial_result · 2012-05-08Clinical Trial Update: Rituximab, Alemtuzumab, and GM-CSF As First-Line Therapy in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating Rituximab, Alemtuzumab, and GM-CSF as first-line therapy in early-stage chronic lymphocytic leukemia has completed …
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CLINICAL_TRIALS withdrawal · 2012-05-03Clinical Trial Update: Cyclophosphamide and Rituximab Followed By Vaccine Therapy in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial of cyclophosphamide and rituximab followed by vaccine therapy for chronic lymphocytic leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-05-02Clinical Trial Update: Immuno-Augmentation With GM-CSF of Pneumococcal Vaccine in Chronic Lymphocytic Leukemia Patients [Phase 2]
Phase 2 clinical trial evaluating GM-CSF immuno-augmentation of pneumococcal vaccination in patients with chronic lymphocytic leukemia; the …
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CLINICAL_TRIALS trial_result · 2012-04-30Clinical Trial Update: LFB-R603 Dose Finding in Patients With Advanced Stage B-Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 dose-finding clinical trial update for LFB-R603 in patients with advanced stage Chronic Lymphocytic Leukemia (Phase 1; completed).
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CLINICAL_TRIALS trial_result · 2012-04-11Clinical Trial Update: Rituximab, Pentostatin, Cyclophosphamide, and Lenalidomide in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial investigating rituximab, pentostatin, cyclophosphamide, and lenalidomide in previously untreated B-cell chronic lymph…
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CLINICAL_TRIALS trial_result · 2012-03-28Clinical Trial Update: Oral LBH589 in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL) [Phase 2]
A Phase 2 study of oral panobinostat (LBH589) in relapsed or refractory chronic lymphocytic leukemia and mantle cell lymphoma has been termi…
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CLINICAL_TRIALS trial_result · 2012-03-13Clinical Trial Update: Green Tea Extract in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated the safety and potential efficacy of oral green tea extract in patients with stage 0 to II chronic lymp…
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CLINICAL_TRIALS trial_result · 2012-02-08Clinical Trial Update: Study of Forodesine Hydrochloride in Patients With Advanced, Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A completed Phase 2 study evaluating forodesine hydrochloride in patients with advanced, fludarabine-refractory chronic lymphocytic leukemia…
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CLINICAL_TRIALS trial_result · 2012-01-27Clinical Trial Update: A Phase I/II, a Single Arm, Open-label Study of Ofatumumab (GSK1841157) in Patients With Previously Treated Chronic Lymphocytic Leukemia [Phase 2]
This is a Phase I/II, single-arm, open-label study of ofatumumab in patients with previously treated chronic lymphocytic leukemia, with resu…
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CLINICAL_TRIALS withdrawal · 2012-01-25Clinical Trial Update: Phase 1B- Open Label Dose-Ranging Study of Oral AFX-2 in Adults With Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1B open-label dose-ranging study of the oral agent AFX-2 in adults with chronic lymphocytic leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-01-23Clinical Trial Update: FCR Versus FC Alone in the Treatment of Chronic Lymphocytic Leukemia (CLL) in Relapsed Patients [Phase 3]
Phase 3 trial comparing FCR (fludarabine, cyclophosphamide, rituximab) versus FC in relapsed chronic lymphocytic leukemia with results poste…
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CLINICAL_TRIALS trial_result · 2012-01-23Clinical Trial Update: Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase II clinical trial of forodesine in chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS withdrawal · 2012-01-11Clinical Trial Update: Frontline Treatment With Bendamustine in Combination With Rituximab in Adults Age 65 or Older With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial of Bendamustine plus Rituximab in adults aged 65 and older with Chronic Lymphocytic Leukemia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2011-12-30Clinical Trial Update: R-CHOP and Alemtuzumab in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial of R-CHOP plus alemtuzumab for chronic lymphocytic leukemia has been withdrawn.
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FDA approval · 2011-12-21FDA Approved: REVLIMID — Supplemental Application (Celgene Corporation)
The FDA approves a supplemental application for Revlimid (lenalidomide) submitted by Celgene Corporation, updating regulatory status for the…
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CLINICAL_TRIALS withdrawal · 2011-12-05Clinical Trial Update: RESPeCT: Revlimid Early Stage Poor Prognosis Chronic Lymphocytic Leukaemia (CLL) Trial [Phase 2]
This clinical trial update notes termination of the RESPeCT study evaluating lenalidomide (Revlimid) in early-stage poor prognosis chronic l…
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CLINICAL_TRIALS trial_result · 2011-11-29Clinical Trial Update: HuMax-CD20 in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients Failing Fludarabine and Alemtuzumab [Phase 2]
Phase 2 clinical trial update showing results for HuMax-CD20 (ofatumumab) in patients with chronic lymphocytic leukemia who failed fludarabi…
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Genasense® (Oblimersen Sodium), Fludarabine, and Rituximab in Subjects With Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
A completed Phase 1/Phase 2 clinical trial assessing Genasense (oblimersen sodium) in combination with fludarabine and rituximab for chronic…
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FDA label_change · 2011-10-28FDA Approved: LEUKERAN — Supplemental Application (Waylis Therapeutics LLC)
FDA supplemental application for Leukeran (chlorambucil) submitted by Waylis Therapeutics LLC.
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CLINICAL_TRIALS trial_result · 2011-10-26Clinical Trial Update: Alemtuzumab and Rituximab in Treating Patients With High-Risk, Early-Stage Chronic Lymphocytic Leukemia [Phase 2]
A phase 2 trial evaluating the combination of alemtuzumab and rituximab in high-risk, early-stage chronic lymphocytic leukemia has completed…
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CLINICAL_TRIALS trial_result · 2011-10-21Clinical Trial Update: Cyclophosphamide, Fludarabine, Alemtuzumab, and Rituximab (CFAR) for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 clinical trial evaluating the CFAR regimen (cyclophosphamide, fludarabine, alemtuzumab, rituximab) in relapsed or refractory chronic…
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CLINICAL_TRIALS trial_result · 2011-10-17Clinical Trial Update: Ofatumumab With Fludarabine and Cyclophosphamide in B-CLL Patients [Phase 2]
Phase 2 study evaluating the combination of ofatumumab with fludarabine and cyclophosphamide in patients with chronic lymphocytic leukemia; …