Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-11-15Clinical Trial Update: Anti-Tac(Fv)-PE38 (LMB-2) to Treat Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating Anti-Tac(Fv)-PE38 (LMB-2) for chronic lymphocytic leukemia completed with results posted.
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia
This clinical trial evaluated non-myeloablative allogeneic stem cell transplantation with matched unrelated donors across several hematologi…
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CLINICAL_TRIALS research · 2012-10-15Clinical Trial Update: A Trial Looking at Ofatumumab for People With Chronic Lymphocytic Leukaemia Who Cannot Have More Intensive Treatment [Phase 3]
A Phase 3 clinical trial update evaluating Ofatumumab for chronic lymphocytic leukemia patients who cannot receive more intensive treatment.
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CLINICAL_TRIALS trial_result · 2012-10-12Clinical Trial Update: Dasatinib in Relapsed Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating dasatinib in relapsed chronic lymphocytic leukemia has been completed with results posted in 2012.
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CLINICAL_TRIALS withdrawal · 2012-10-10Clinical Trial Update: Arsenic Trioxide in Treating Patients With Refractory or Relapsed Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial of arsenic trioxide for refractory or relapsed chronic lymphocytic leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: Dose-finding Trial of HCD122 in Patients With Chronic Lymphocytic Leukemia (CLL) That is Relapsed or Non-responsive to Prior Fludaribine Therapy [Phase 1]
Phase 1 dose-finding study of HCD122 in Chronic Lymphocytic Leukemia patients who relapsed or failed prior fludarabine therapy has been term…
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CLINICAL_TRIALS withdrawal · 2012-09-07Clinical Trial Update: A Phase 2, Single-Arm, Open-Label Study Evaluating the Efficacy and Safety of Single Agent GS 1101 (CAL 101) as Therapy for Previously Treated Chronic Lymphocytic Leukemia [Phase 2]
Phase 2, single-arm, open-label study evaluating GS-1101 (CAL-101) for previously treated chronic lymphocytic leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies [Phase 1]
Phase 1 dose-escalation study of CAL-101 in relapsed or refractory hematologic malignancies has completed, evaluating safety and preliminary…
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation [NA]
This clinical trial evaluated CD8 donor lymphocyte infusion for relapse or residual disease after allogeneic stem cell transplantation. The …
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CLINICAL_TRIALS trial_result · 2012-08-22Clinical Trial Update: EL625 in Persistent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
A Phase 2 study of EL625 in patients with persistent chronic lymphocytic leukemia or small lymphocytic lymphoma was terminated, with results…
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CLINICAL_TRIALS research · 2012-08-22Clinical Trial Update: Trial of FFP+HDMP+Rituximab for Ultra-high Risk Chronic Lymphocytic Leukemia [Phase 3]
An update on a Phase 3 trial of a FFP+HDMP+Rituximab regimen for ultra-high-risk chronic lymphocytic leukemia; current status details are no…
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CLINICAL_TRIALS trial_result · 2012-08-10Clinical Trial Update: Subcutaneous Alemtuzumab (CAMPATH®, MabCampath®) in Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial update reporting results for subcutaneous alemtuzumab (CAMPATH, MabCampath) in relapsed/refractory B-cell chronic lymphocytic …
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CLINICAL_TRIALS trial_result · 2012-08-06Clinical Trial Update: Bendamustine Hydrochloride Injection for Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
Clinical trial update for bendamustine hydrochloride injection in previously untreated chronic lymphocytic leukemia (Phase 3).
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CLINICAL_TRIALS withdrawal · 2012-08-03Clinical Trial Update: Reactogenicity, Immunogenicity of Trivalent Influenza Vaccine With Recombinant Interferon Alpha Among Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
This document reports the withdrawal of a Phase 1/2 trial evaluating a trivalent influenza vaccine combined with recombinant interferon alph…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Allo Transplantation With Mylotarg, Fludarabine and Melphalan for AML, CML and MDS [Phase 1, Phase 2]
An allogeneic transplant regimen using Mylotarg with fludarabine and melphalan was studied for acute myeloid leukemia, chronic myeloid leuke…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Study of Weekly Clofarabine for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 study evaluating weekly clofarabine for relapsed/refractory chronic lymphocytic leukemia has been terminated.
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CLINICAL_TRIALS withdrawal · 2012-08-01Clinical Trial Update: Oral Clofarabine in Chronic Lymphocytic Leukemia (CLL) [Phase 1]
A Phase 1 study of oral clofarabine for chronic lymphocytic leukemia has been withdrawn (sponsored by MD Anderson Cancer Center).
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Oral Valganciclovir Versus Valacyclovir [Phase 2]
A Phase 2 clinical trial comparing oral valganciclovir versus valacyclovir in patients with chronic lymphocytic leukemia and leukemia, which…
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Continuous Infusion of Campath-1H Followed by Subcutaneous Injections in Previously Treated Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial update of continuous infusion Campath-1H (alemtuzumab) followed by subcutaneous injections in previously treated chro…
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CLINICAL_TRIALS trial_result · 2012-07-31Clinical Trial Update: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
This clinical trial investigates a combination of chemotherapy with peripheral stem cell transplantation to treat refractory chronic lymphoc…
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FDA approval · 2012-06-26FDA Approved: TREANDA — Supplemental Application (Cephalon, LLC)
FDA approved a supplemental application for TREANDA (bendamustine hydrochloride) submitted by Cephalon, LLC.
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Efficacy and Safety of Ofatumumab Retreatment and Maintenance Treatment in Patients With B-cell Chronic Lymphocytic Leukemia (CLL) [Phase 4]
A Phase 4 clinical trial evaluated retreatment and maintenance therapy with ofatumumab in patients with chronic lymphocytic leukemia, with r…
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CLINICAL_TRIALS trial_result · 2012-06-11Clinical Trial Update: Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating SDX-101 (R-Etodolac) with chlorambucil and chlorambucil alone in chronic lymphocytic leukemia. The study status is …
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CLINICAL_TRIALS research · 2012-06-07Clinical Trial Update: Low Dose CdA Combined With Valproic Acid (VPA) in Previously Treated B-cell Chronic Lymphocytic Leukemia(B-CLL) [Phase 1, Phase 2]
This is an update on an ongoing Phase 1/2 trial of low-dose cladribine (CdA) in combination with valproic acid for previously treated chroni…
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CLINICAL_TRIALS trial_result · 2012-05-23Clinical Trial Update: Treatment of Chronic Lymphocytic B-Leukemia With IL-2 and CD-40 Autologous Tumor Cells [Phase 1]
A Phase 1 clinical trial evaluating interleukin-2 in combination with CD-40–activated autologous tumor cells for chronic lymphocytic leukemi…