Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: NOX-A12 in Combination With Bendamustine and Rituximab in Relapsed Chronic Lymphocytic Leukemia (CLL) [Phase 2]
This clinical trial update reports completion of a Phase 2 study evaluating NOX-A12 in combination with bendamustine and rituximab for relap…
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: A Study of Idelalisib and Rituximab in Elderly Patients With Untreated CLL or SLL [Phase 2]
Phase 2 trial of idelalisib plus rituximab in elderly patients with untreated CLL or SLL; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating cyclophosphamide as GVHD prophylaxis after allogeneic peripheral blood stem cell transplantation in patients with h…
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: Penostatin, Rituximab and Ontak and Allogeneic Natural Killer (NK) Cells for Refractory Lymphoid Malignancies [Phase 2]
Phase 2 trial update evaluating Penostatin, Rituximab, Ontak, and allogeneic NK cells in refractory lymphoid malignancies has completed with…
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CLINICAL_TRIALS trial_result · 2017-05-18Clinical Trial Update: Lenalidomide in Patients With Chronic Lymphocytic Leukemia Older Than 65 Years of Age [Phase 2]
Phase 2 clinical trial evaluating lenalidomide in older patients with chronic lymphocytic leukemia. The study results have been posted.
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomarkers in Samples From Patients With Chronic Lymphocytic Leukemia Treated on Clinical Trial ECOG-2997
A biomarker analysis update using samples from patients with chronic lymphocytic leukemia treated on the ECOG-2997 clinical trial.
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Biomarkers in DNA Samples From Patients With Chronic Lymphocytic Leukemia Previously Treated With Fludarabine-Based Therapy
This clinical trial update reports on biomarker analyses using DNA samples from patients with chronic lymphocytic leukemia who had prior flu…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and tolerability of HSC835 in patients with various hematologic malignancies completed with results posted …
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia
A clinical trial update concerning C-X-C chemokine receptor 4 in chronic lymphocytic leukemia, sponsored by Assiut University.
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluated haploidentical allogeneic transplantation with post-transplant regulatory T-cell infusion in…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Efficacy and Safety of Idelalisib in Combination With Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia With 17p Deletion [Phase 2]
Phase 2 trial assessing idelalisib plus rituximab in previously untreated CLL with 17p deletion; study terminated with posted results in 201…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Pilot Study of Lymphoid Tumor Microenvironmental Dysruption Prior to Autologous Stem Cell Transplantation [Phase 1]
A Phase 1 pilot study evaluating disruption of the lymphoid tumor microenvironment prior to autologous stem cell transplantation was termina…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating pentostatin and lymphocyte infusion to prevent graft rejection after donor stem cell transplantation—compl…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Non-Myeloablative Allogeneic HSCT From HLA Matched Related or Unrelated Donors for the Treatment of Low Grade B Cell Malignancies [Phase 2, Phase 3]
A phase 2/3 trial evaluating non-myeloablative allogeneic HSCT from HLA-matched related or unrelated donors in low-grade B-cell malignancies…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Open-Label Study of Lenalidomide in Combination With Oral Dexamethasone in the Treatment of Previously Untreated, Symptomatic Patients With Chronic Lymphocytic Leukemia [Phase 2]
An open-label Phase 2 trial evaluating lenalidomide in combination with oral dexamethasone for previously untreated, symptomatic chronic lym…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors [Phase 2]
Phase 2 clinical trial evaluating the combination of plerixafor and GM-CSF (sargramostim) for mobilizing hematopoietic stem cells from allog…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial evaluating donor stem cell transplantation for high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma has comple…
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CLINICAL_TRIALS withdrawal · 2017-04-28Clinical Trial Update: Evaluation of the Immune Restoration Potential Of Lenalidomide [Phase 2]
A Phase 2 trial evaluating lenalidomide for immune restoration in Chronic Lymphocytic Leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: A Phase I, Multicenter, Dose Escalation Study of CAT-8015 in Participants With Chronic Leukemia [Phase 1]
A Phase I dose-escalation study of CAT-8015 (moxetumomab pasudotox) in participants with chronic leukemia; the trial was terminated and resu…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Study of Immune Responses to Influenza Vaccination With or Without Imiquimod Application in Untreated CLL Patients [Phase 2]
Phase 2 trial assessing immune responses to influenza vaccination in untreated Chronic Lymphocytic Leukemia patients with or without Imiquim…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Study of Intravenously Administered SNS-032 in Patients With Advanced B-lymphoid Malignancies [Phase 1]
A Phase 1 clinical trial update reports the completion of a study evaluating intravenously administered SNS-032 in patients with advanced B-…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs [Phase 2]
A Phase 2 safety and tolerability trial evaluating CDX-301 with or without plerixafor for stem cell mobilization in matched related donor/re…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders [Phase 2]
Phase 2 clinical trial evaluating nonmyeloablative allogeneic stem cell transplantation for various hematologic disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Tipifarnib in Treating Patients With Anemia or Neutropenia and Large Granular Lymphocyte Leukemia [Phase 2]
Phase 2 trial evaluating tipifarnib in patients with anemia or neutropenia and large granular lymphocytic leukemia, including chronic lympho…
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CLINICAL_TRIALS withdrawal · 2017-04-05Clinical Trial Update: Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, Prolymphocytic Leukemia, or Richter's Transformation [Phase 2]
This clinical trial update reports that the Phase 2 study of Sotrastaurin acetate for relapsed or refractory chronic lymphocytic leukemia, s…