Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: Study Evaluating the Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL) (Tugela ) [Phase 3]
A Phase 3 trial evaluating idelalisib in combination with bendamustine and rituximab for previously treated chronic lymphocytic leukemia has…
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Dasatinib in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating dasatinib for chronic lymphocytic leukemia (refractory and various stages) has completed with results post…
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CLINICAL_TRIALS trial_result · 2018-02-08Clinical Trial Update: Vorinostat, Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a Vorinostat-containing regimen (vorinostat, fludarabine phosphate, cyclophosphamide, and rituximab) i…
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FDA approval · 2018-02-06FDA Approved: ZYDELIG — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for ZYDELIG (idelalisib) filed by Gilead Sciences, Inc.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Lenalidomide + Plerixafor in Previously Treated Chronic Lymphocytic Leukemia (CLL) [Phase 1]
Phase 1 trial of lenalidomide plus plerixafor in previously treated chronic lymphocytic leukemia has completed with results posted.
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FDA approval · 2018-01-26FDA Approved: ZYDELIG — Supplemental Application (Gilead Sciences, Inc.)
FDA approved a supplemental application for ZYDELIG (idelalisib) by Gilead Sciences, Inc.
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT [Phase 2]
Phase 2 trial evaluating post-transplant cyclophosphamide as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell …
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CLINICAL_TRIALS trial_result · 2017-12-21Clinical Trial Update: A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating obinutuzumab plus bendamustine in previously untreated chronic lymphocytic leukemia has completed with results post…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating fludarabine phosphate with total-body irradiation as conditioning before donor peripheral blood stem cell transplan…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: A Pilot Trial With Subcutaneous Alemtuzumab and Oral Fludarabinephosphate for the Determination of Safety, Efficacy and Molecular Profiling for the Prediction of Response [Phase 2]
Phase 2 trial evaluating subcutaneous alemtuzumab with oral fludarabine phosphate for safety, efficacy, and molecular profiling to predict r…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating autologous stem cell transplant followed by donor stem cell transplant in relapsed or refractory lymphom…
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS withdrawal · 2017-12-02Clinical Trial Update: T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies [Phase 1, Phase 2]
A trial investigating T-regulatory cell and CD3-depleted double umbilical cord blood transplantation for hematologic malignancies has been w…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Yttrium Y 90 Anti-CD19 Antibody BU-12 in Patients With Advanced Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 trial of BU-12, a Yttrium-90 labeled anti-CD19 antibody, in advanced relapsed or refractory acute lymphoblastic leukemia or chronic …
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Study to Assess the Effect of Rifampin on the Metabolism of Navitoclax [Phase 1]
Phase 1 trial update evaluating the effect of rifampin on navitoclax metabolism; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Ofatumumab in Japanese Patients With CD20 Positive Follicular Lymphoma or Chronic Lymphocytic Leukemia [Phase 1]
This is a Phase 1 clinical trial update for the anti-CD20 antibody ofatumumab in Japanese patients with CD20-positive follicular lymphoma or…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia. [Phase 1]
This update reports the completion of a Phase 1 trial evaluating lenalidomide in acute myeloid leukemia, acute lymphoblastic leukemia, and c…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma [Phase 2]
This Phase 2 trial evaluated the combination of vorinostat, cladribine, and rituximab in patients with mantle cell lymphoma, relapsed chroni…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects [Phase 1]
A Phase 1 study evaluating the effect of ofatumumab on cardiac repolarization (QTc) in patients with fludarabine-refractory chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: Chemotherapy, Total-Body Irradiation, Rituximab, and Donor Stem Cell Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
This Phase 2 study evaluated a conditioning regimen combining chemotherapy, total-body irradiation, and rituximab followed by donor stem cel…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Tositumomab and Iodine I 131 Tositumomab in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma in First Remission [Phase 2]
This clinical trial update reports Phase 2 results for tositumomab in combination with iodine-131 for treating chronic lymphocytic leukemia …
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CLINICAL_TRIALS trial_result · 2017-10-11Clinical Trial Update: Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab in Adults With Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial evaluating idelalisib in combination with bendamustine and rituximab for previously untreated chronic lymphocytic leukemia h…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: CD19-specific T-cell for Chronic Lymphocytic Leukemia (CLL) [Phase 1]
Phase 1 trial evaluating CD19-specific T-cell therapy for Chronic Lymphocytic Leukemia has completed.
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CLINICAL_TRIALS research · 2017-08-10Clinical Trial Update: Analysis of Genetic Factors Related to Predisposition and Prognosis of Hematological Malignancies in Israel
A completed Israeli clinical trial analyzing genetic factors associated with predisposition and prognosis of hematologic malignancies, inclu…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant [Phase 2]
Phase 2 clinical trial update assessing safety and tolerability of HSC835 in patients with hematological malignancies undergoing single umbi…